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AUTHORS: Czarnetzki, Christoph MD, MBA et al Anesthesia & Analgesia: December 17, 2020 – Volume – Issue – 10.1213 BACKGROUND: Succinylcholine remains the muscle relaxant of choice for rapid sequence induction (RSI) but has many adverse effects. High-dose rocuronium bromide may be an alternative to succinylcholine for RSI but recovery times are nearly doubled compared with […]
Read MoreAUTHORS: Komatsu, Ryu MD, MS et al Anesthesia & Analgesia: October 28, 2020 – Volume – Issue – 10.1213 BACKGROUND: Statins possess pleiotropic effects, which potentially benefit noncardiovascular conditions. Previous work suggests that statins reduce inflammation and prevent acute respiratory distress syndrome and infections. However, there is a paucity of data regarding potential benefits of statins […]
Read MoreAuthor: Michael Walter Cardiovascular Business Young, healthy adults who smoke marijuana may face a heightened risk of developing cardiovascular disease (CVD) later in life, according to new findings published in the Journal of Applied Physiology. “This is an exciting field of research given the ubiquity of cannabis use and the knowledge gap that exists, it’s a […]
Read MoreAUTHORS: Christensen, Anna L. PhD et al Anesthesia & Analgesia: November 23, 2020 – Volume – Issue – 10.1213 BACKGROUND: Intraoperative hypotension is common and associated with organ injury and death, although randomized data showing a causal relationship remain sparse. A risk-adjusted measure of intraoperative hypotension may therefore contribute to quality improvement efforts. METHODS: The measure […]
Read MoreAUTHORS: Schopfer, Leonore MMSc et al Anesthesia & Analgesia: January 6, 2021 – Volume – Issue – 10.1213 BACKGROUND: Mechanical ventilation interferes with cerebral perfusion via changes in intrathoracic pressure and/or as a consequence of alterations in CO2. Cerebral vascular vasoreactivity is dependent on CO2, and hypocapnia can potentially lead to vasoconstriction and subsequent decrease in […]
Read MoreAUTHORS: Willer, Brittany L. MD et al Anesthesia & Analgesia: March 2021 – Volume 132 – Issue 3 – p 679-685 BACKGROUND: Failure to rescue (FTR) and unplanned reoperation following an index surgical procedure are key indicators of the quality of surgical care. Given that differences in unplanned reoperation and FTR rates among racial groups may […]
Read MoreAUTHORS: Jansen, Gerrit Dr med et al Anesthesia & Analgesia: November 30, 2020 – Volume – Issue – 10.1213 BACKGROUND: Recently, a very low incidence of 3 per 10,000 and a mortality of 30% were reported for pediatric perioperative cardiac arrest (POCA). However, high-risk patients, namely children already anesthetized on the intensive care unit (ICU), were […]
Read MoreAUTHORS: Lankford, Allison S. MD et al Anesthesia & Analgesia: March 2021 – Volume 132 – Issue 3 – p 777-787 BACKGROUND: The use of extracorporeal membrane oxygenation (ECMO) as a rescue therapy for cardiopulmonary failure is expanding in critical care medicine. In this case series, we describe the clinical outcomes of 21 consecutive pregnant or […]
Read MoreAUTHORS: Lee, Seung-Hwa MD et al Anesthesia & Analgesia: April 2021 – Volume 132 – Issue 4 – p 960-968 BACKGROUND: Despite an association between obesity and increased risks for various diseases, obesity has been paradoxically reported to correlate with improved mortality in patients with established cardiovascular disease. However, its effect has not been evaluated to […]
Read MoreAUTHORS: Ortved, Milla MD et al Anesthesia & Analgesia: November 20, 2020 – Volume – Issue – 10 BACKGROUND: Diabetes increases the risk of adverse outcomes in surgical procedures, including total hip and knee arthroplasty (THA/TKA), and the prevalence of diabetic patients undergoing these procedures is high, ranging from approximately 8% to 20%. However, there is […]
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