Author: Dr Clemens

Uncategorized Published - 22 June, 2021    By - Dr Clemens
Intraoperative Hypotension Is Associated With Adverse Clinical Outcomes After Noncardiac Surgery

AUTHORS: Gregory, Anne MD, MSc, FRCPC et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1654-1665 BACKGROUND:  Intraoperative hypotension (IOH) occurs frequently during surgery and may be associated with organ ischemia; however, few multicenter studies report data regarding its associations with adverse postoperative outcomes across varying hemodynamic thresholds. Additionally, no […]

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Uncategorized Published - 22 June, 2021    By - Dr Clemens
Propofol for Induction and Maintenance of Anesthesia in Patients With Brugada Syndrome

AUTHORS: Flamée, Panagiotis MD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1645-1653 BACKGROUND:  Propofol administration in patients with Brugada syndrome (BrS) is still a matter of debate. Despite lacking evidence for its feared arrhythmogenicity, up to date, expert cardiologists recommend avoiding propofol. The main aim of this […]

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Uncategorized Published - 22 June, 2021    By - Dr Clemens
Association Between Antifibrinolytic Therapy and Perioperative Outcomes in Patients With Coronary Artery Stents Undergoing Noncardiac Surgery

AUTHORS: Boswell, Michael R. MD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1635-1644 BACKGROUND:  Patients with existing coronary artery stents are at an increased risk for major adverse cardiac events (MACEs) when undergoing noncardiac surgery (NCS). Although the use of antifibrinolytic (AF) therapy in NCS has significantly increased […]

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Uncategorized Published - 22 June, 2021    By - Dr Clemens
Comparison of Liposomal Bupivacaine and Conventional Local Anesthetic Agents in Regional Anesthesia

AUTHORS: Jin, Zhaosheng MBBS et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1626-1634 BACKGROUND:  Pain is one of the most common adverse events after surgery. Regional anesthesia techniques are effective for pain control but have limited duration of action. Liposomal bupivacaine is a long-acting formulation of bupivacaine. We conduct […]

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Uncategorized Published - 21 June, 2021    By - Dr Clemens
Phrenic Nerve Block at the Azygos Vein Level Versus Sham Block for Ipsilateral Shoulder Pain After Video-Assisted Thoracoscopic Surgery

AUTHORS: Kimura Kuroiwa, Kaori MD, PhD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1594-1602 BACKGROUND:  Ipsilateral shoulder pain (ISP) is a common problem after pulmonary surgery. We hypothesized that phrenic nerve block (PNB) at the azygos vein level, near the location of the surgical operation, would be effective […]

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Uncategorized Published - 21 June, 2021    By - Dr Clemens
Free Hemoglobin Ratio as a Novel Biomarker of Acute Kidney Injury After On-Pump Cardiac Surgery

AUTHORS: Hu, Jie MD, PhD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1548-1558 BACKGROUND:  Cardiac surgery with cardiopulmonary bypass (CPB) is associated with a high risk of postoperative acute kidney injury (AKI). Due to limitations of current diagnostic strategies, we sought to determine whether free hemoglobin (fHb) ratio […]

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Uncategorized Published - 21 June, 2021    By - Dr Clemens
A Survey of the Society for Pediatric Anesthesia on the Use, Monitoring, and Antagonism of Neuromuscular Blockade

AUTHORS: Faulk, Debra J. MD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1518-1526 BACKGROUND:  Although the package insert clearly states that “the safety and efficacy of sugammadex in pediatric patients have not been established,” we hypothesized that sugammadex is used widely in pediatric anesthetic practice supplanting neostigmine as […]

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Uncategorized Published - 21 June, 2021    By - Dr Clemens
Quantitative Pupillometry as a Predictor of Pediatric Postoperative Opioid–Induced Respiratory Depression

AUTHORS: Packiasabapathy, Senthil MD et al Anesthesia & Analgesia: May 2021 BACKGROUND: Safe postoperative pain relief with opioids is an unmet critical medical need in children. There is a lack of objective, noninvasive bedside tool to assess central nervous system (CNS) effects of intraoperative opioids. Proactive identification of children at risk for postoperative respiratory depression (RD) […]

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Uncategorized Published - 21 June, 2021    By - Dr Clemens
Predictive Performance of Oximetry to Detect Sleep Apnea in Patients Taking Opioids

AUTHORS:  Waseem, Rida MA et al Anesthesia & Analgesia: May 2021 BACKGROUND: Long-term use of opioids for treatment of chronic pain is associated with significant risks including worsening unrecognized or untreated sleep apnea that may increase morbidity and mortality. Overnight oximetry has been validated for predicting sleep apnea in surgical and sleep clinic patients. The objective […]

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Uncategorized Published - 18 June, 2021    By - Dr Clemens
Invasiveness of Treatment Is Gender Dependent in Intensive Care

AUTHORS: Blecha, Sebastian MD et al Anesthesia & Analgesia: June 2021 – Volume 132 – Issue 6 – p 1677-1683 BACKGROUND:  Health care and outcome of critically ill patients are marked by gender-related differences. Several studies have shown that male patients in intensive care units (ICU) more often receive mechanical ventilation, dialysis, pulmonary arterial catheterization (PAC), […]

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