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Authors: Ya-Ting Du, M.D. et al Anesthesiology June 2021. Background Experimental and observational research suggests that combined epidural–general anesthesia may improve long-term survival after cancer surgery by reducing anesthetic and opioid consumption and by blunting surgery-related inflammation. This study therefore tested the primary hypothesis that combined epidural–general anesthesia improves long-term survival in elderly patients. Methods […]
Read MoreAuthors: Natalie Melton, M.D., F.R.C.P.C. et al Anesthesiology June 2021. Background Peripheral nerve blocks are being used with increasing frequency for management of hip fracture–related pain. Despite converging evidence that nerve blocks may be beneficial, safety data are lacking. This study hypothesized that peripheral nerve block receipt would not be associated with adverse events potentially […]
Read MoreDG Journal Club Authors: Magdalena Gostian, Johannes Loeser et al. JAMA Otolaryngol Head Neck Surg. 2021 Jun 1; 147(6): 553-560 Importance Up to 80% of patients with head and neck cancer undergoing ablative surgery and neck dissection develop postoperative pain with detrimental effects on quality of life that also contributes to neuropathic and chronic postoperative […]
Read MoreDG Journal Club AUTHORS: Akihito Minamide, Munehito Yoshida et al. Clin Spine Surg. 2021 Jun 14 STUDY DESIGN This was a retrospective cohort study. OBJECTIVE The objective of this study was to characterize the long-term clinical and radiographic results of articular segmental decompression surgery using endoscopy [cervical microendoscopic laminotomy (CMEL)] for cervical spondylotic myelopathy (CSM) […]
Read MoreAuthors: Matthew Badali, PharmD and Jacqueline Cleary, PharmD, BCACP Pratical Pain Manament Volume 21 Issue 3 Acid-sensing ion channel inhibitors and insulin growth factor-1 offer new tools in chronic migraine care – especially for patients refractory to traditional medications. Acid-sensing Ion Channel Inhibitors May Treat and Prevent Migraine Refractory to Traditional Medications ASIC Inhibitors in a Snapshot […]
Read MoreAuthors: Ya-Wei Li, M.D. et al Anesthesiology June 2021. Background Delirium is a common and serious postoperative complication, especially in the elderly. Epidural anesthesia may reduce delirium by improving analgesia, reducing opioid consumption, and blunting stress response to surgery. This trial therefore tested the hypothesis that combined epidural–general anesthesia reduces the incidence of postoperative delirium […]
Read MoreAuthors: Veena Graff, M.D. et al Anesthesiology July 2021, Vol. 135, 111–121. Background Calls to better involve patients in decisions about anesthesia—e.g., through shared decision-making—are intensifying. However, several features of anesthesia consultation make it unclear how patients should participate in decisions. Evaluating the feasibility and desirability of carrying out shared decision-making in anesthesia requires better […]
Read MoreAuthor: Keith M. Vogt, M.D., Ph.D. et al Anesthesiology July 2021, Vol. 135, 69–82. Background Despite the well-known clinical effects of midazolam and ketamine, including sedation and memory impairment, the neural mechanisms of these distinct drugs in humans are incompletely understood. The authors hypothesized that both drugs would decrease recollection memory, task-related brain activity, and […]
Read MoreAuthors: Stephen C. Haskins, M.D. et al Anesthesiology June 2021. Background Hip arthroscopy is associated with moderate to severe postoperative pain. This prospective, randomized, double-blinded study investigates the clinically analgesic effect of anterior quadratus lumborum block with multimodal analgesia compared to multimodal analgesia alone. The authors hypothesized that an anterior quadratus lumborum block with multimodal […]
Read MoreBy Gerard Limerick, MD, PhD and Tina L. Doshi, MD, MHS Practical Pain Management Volume 21 Issue 3 The new class of CGRPs may also benefit patients living with chronic pain from trigeminal neuralgia, temporomandibular disorders, diabetic peripheral neuropathy, chemotherapy-induced neuropathy, and fibromyalgia. A review of the data to date. Calcitonin gene-related peptide (CGRP) antagonists have been a […]
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