Author: Dr Clemens

Uncategorized Published - 10 March, 2022    By - Dr Clemens
The Burden of Coronavirus Disease 2019–Related Cases, Hospitalizations, and Mortality Based on Vaccination Status and Mandated Mask Use

AUTHORS: Abd-Elsayed, Alaa MD et al Anesthesia & Analgesia: March 2022 – Volume 134 – Issue 3 – p 524-531 BACKGROUND:  Coronavirus disease 2019 (COVID-19) cases continue to surge in the United States with the emergence of new variants. Statewide variability and inconsistency in implementing risk mitigation strategies are widespread, particularly in regards to enforcing mask […]

Read More
Uncategorized Published - 9 March, 2022    By - Dr Clemens
Evaluation of the Duration of Preanesthesia Consultation

AUTHORS: Compère, Vincent MD, PhD et al Anesthesia & Analgesia: March 2022 – Volume 134 – Issue 3 – p 496-504 BACKGROUND:  The time allocated to the preanesthesia consultation (PAC) of a patient undergoing an elective surgical procedure is an important factor to optimize consultation sessions. The main objective of this study was to build a […]

Read More
Uncategorized Published - 9 March, 2022    By - Dr Clemens
The Perioperative Use of Benzodiazepines for Major Orthopedic Surgery in the United States

AUTHORS: Cozowicz, Crispiana MD et al Anesthesia & Analgesia: March 2022 – Volume 134 – Issue 3 – p 486-495 BACKGROUND:  Despite numerous indications for perioperative benzodiazepine use, associated risks may be exacerbated in elderly and comorbid patients. In the absence of national utilization data, we aimed to describe utilization patterns using national claims data from […]

Read More
Uncategorized Published - 9 March, 2022    By - Dr Clemens
Clonidine Versus Midazolam Premedication and Postoperative Negative Behavioral Changes in Younger Children

AUTHORS: Zickerman, Caroline MD et al Anesthesia & Analgesia: February 2022 BACKGROUND: Postoperative negative behavioral changes (NBCs) are common among children, but risk for this is thought to be reduced with premedication. Midazolam has for many years been a standard premedication for children. More recently, the alpha-2 adrenergic agonist clonidine has also become popular as a […]

Read More
Uncategorized Published - 9 March, 2022    By - Dr Clemens
Population Pharmacokinetic Model for Tramadol and O-desmethyltramadol in Older Patients

DG Journal Club AUTHORS: Aymen A Al-Qurain, Richard N Upton et al. Eur J Drug Metab Pharmacokinet. 2022 Feb BACKGROUND AND OBJECTIVES Tramadol is commonly prescribed to manage chronic pain in older patients. However, there is a gap in the literature describing the pharmacokinetic parameters for tramadol and its active metabolite (O-desmethyltramadol [ODT]) in this […]

Read More
Uncategorized Published - 9 March, 2022    By - Dr Clemens
Study finds link between chronic pain and disrupted eating

Author: Annie Lennon MedicalNewsToday Researchers investigated how lower back pain interacts with eating behavior via behavioral and neuroimaging experiments. They found that pain alters food satiety in those who have chronic lower back pain and those who have recovered from subacute back pain. Further studies are necessary to understand the mechanisms behind their results. Studies […]

Read More
Uncategorized Published - 8 March, 2022    By - Dr Clemens
Use of Epidural in Childbirth Is Linked to Decreased Severe Maternal Morbidity

DG News In a study of vaginal births in New York State hospitals, labour neuraxial analgesia  was associated with a decreased risk of severe maternal morbidity. Deliveries with a neuraxial analgesia also lessened the risk of postpartum haemorrhage, the leading cause of preventable severe maternal morbidity, according to Jean Guglielminotti, MD, Columbia University Mailman School […]

Read More
Uncategorized Published - 8 March, 2022    By - Dr Clemens
Early Vasopressor Utilization Strategies and Outcomes in Critically Ill Patients With Severe Traumatic Brain Injury

AUTHORS: Toro, Camilo BA et al Anesthesia & Analgesia: February 2022 BACKGROUND: Early hypotension after severe traumatic brain injury (sTBI) is associated with increased mortality and poor long-term outcomes. Current guidelines suggest the use of intravenous vasopressors, commonly norepinephrine and phenylephrine, to support blood pressure after TBI. However, guidelines do not specify vasopressor type, resulting in […]

Read More
Uncategorized Published - 8 March, 2022    By - Dr Clemens
Association Between Perioperative Medication Use and Postoperative Delirium and Cognition in Older Adults Undergoing Elective Noncardiac Surgery

AUTHORS: Duprey, Matthew S. PharmD, PhD et al Anesthesia & Analgesia: February 2022 BACKGROUND: Postoperative delirium is frequent in older adults and is associated with postoperative neurocognitive disorder (PND). Studies evaluating perioperative medication use and delirium have generally evaluated medications in aggregate and been poorly controlled; the association between perioperative medication use and PND remains unclear. […]

Read More
Uncategorized Published - 8 March, 2022    By - Dr Clemens
Efficacy and safety of transcutaneous electrical nerve stimulation (TENS) for acute and chronic pain in adults

AUTHORS: Mark I Johnson, Carole A Paley et al. BMJ Open. 2022 Feb 10 OBJECTIVE To investigate the efficacy and safety of transcutaneous electrical nerve stimulation (TENS) for relief of pain in adults. DESIGN Systematic review and meta-analysis. DATA SOURCES Medline, Cochrane Central, Embase (and others) from inception to July 2019 and updated on 17 […]

Read More