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AUTHORS: Cronjé, Larissa FCA et al Anesthesia & Analgesia: April 2022 – Volume 134 – Issue 4 – p 728-739 BACKGROUND: Severe anesthetic-related critical incident (SARCI) monitoring is an essential component of safe, quality anesthetic care. Predominantly retrospective data from low- and middle-income countries (LMICs) report higher incidence but similar types of SARCI compared to high-income […]
Read MoreDG Journal Club AUTHORS: David Amar et al Anesthesiology. 2022 Mar BACKGROUND Postoperative atrial fibrillation (AF) may identify patients at risk of subsequent AF, with its greater risk of stroke. We hypothesized that N-acetylcysteine mitigates inflammation and oxidative stress to reduce the incidence of postoperative AF. METHODS In this double-blind, placebo-controlled trial, patients at high […]
Read MoreAUTHORS: Murugesan, Saravanakumar PhD et al Anesthesia & Analgesia: April 2022 – Volume 134 – Issue 4 – p 713-723 BACKGROUND: Preeclampsia (PE) manifesting as hypertension and organ injury is mediated by vascular dysfunction. In biological fluids, extracellular vesicles (EVs) containing microRNA (miRNA), protein, and other cargo released from the placenta may serve as carriers to […]
Read MoreDG Journal Club AUTHORS: Stephanie FranzC)n et al Br J Anaesth. 2022 Mar BACKGROUND The choice of anaesthetic may influence regulation of renal perfusion and function. We investigated renal function in patients anaesthetised with propofol or sevoflurane before surgery and postoperatively. METHODS Patients with ASA physical status 1-2 planned for spinal surgery were randomised to […]
Read MoreAuthors: Karen E. A. Burns, MD MSc et al JAMA March 23, 2021 Key Points Question In critically ill patients who receive invasive mechanical ventilation, how is invasive mechanical ventilation discontinued and do discontinuation practices differ internationally? Findings In this prospective observational study that included 1868 patients from 142 intensive care units in Canada, Europe, the US, […]
Read MoreAuthor: Michael Walter Cardiovascular Business Patient outcomes after transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) do not significantly change based on the time of day the procedure takes place, according to new findings published in Circulation: Cardiovascular Quality and Outcomes. Pointing to a single-center analysis that found SAVR outcomes may improve in […]
Read MoreAuthor: Tony Mira F1rstNews Summary: When the anesthesia provider opts for monitored anesthesia care in a patient case, what is he/she really signing on to? This anesthesia technique is a bit slippery in terms of identification, requirements and even payment. Several months ago, we published an article on the three anesthesia techniques available to anesthesiologists and […]
Read MoreAUTHORS: Nasr, Viviane G. MD, MPH et al Anesthesia & Analgesia: March 2022 – Volume 134 – Issue 3 – p 532-539 BACKGROUND: With advances in surgical and catheter-based interventions and technologies in patients with congenital heart disease (CHD), the practice of pediatric cardiac anesthesiology has evolved in parallel with pediatric cardiac surgery and pediatric cardiology […]
Read MoreAuthors: Vincenzo Russotto MD et al JAMA March 23, 2021 Key Points Question Among critically ill patients undergoing tracheal intubation worldwide, how common are major adverse events during the peri-intubation period? Findings In this prospective observational study that included 2964 patients from 197 sites across 29 countries from October 2018 to July 2019, at least one major […]
Read MoreDG Journal Club AUTHORS: Yan Sun, Zhilin Wu, ShuJun Sun, Rui Chen J Clin Pharmacol. 2022 Feb 27 [Epub ahead of print] Dexmedetomidine has been identified as a useful adjunct to improve the effect of nerve blocks in adults, however, its effect for children is not fully investigated. This meta-analysis is aimed to evaluate the […]
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