Author: Dr Clemens

Uncategorized Published - 12 August, 2022    By - Dr Clemens
As overdose deaths exploded during the pandemic, racial disparities widened, CDC report shows

Author: Andrew Joseph STAT As U.S. overdose deaths soared to devastating new heights in the first year of the pandemic, racial disparities widened sharply, with rates spiking much more among Black people and American Indians and Alaska Natives than among white people, according to a federal report released Tuesday. While overall overdose deaths increased by 30% from 2019 […]

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Uncategorized Published - 12 August, 2022    By - Dr Clemens
Interactions of the protease inhibitor, ritonavir, with common anesthesia drugs

DG Journal Club Anders Svedmyr, Henrik Hack, Brian J Anderson Paediatr Anaesth. 2022 Jul 17 The protease inhibitor, ritonavir, is a strong inhibitor of CYP 3A. The drug is used for management of the human immunovirus and is currently part of an oral antiviral drug combination (nirmatrelvir-ritonavir) for the early treatment of SARS-2 COVID-19-positive patients […]

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Uncategorized Published - 12 August, 2022    By - Dr Clemens
Best pain medication for severe arthritis

Author: Suchandrima Bhowmik MedicalNewsToday Arthritis is a chronic inflammation of the joint that affects people worldwide. Doctors will create treatment plans for people based on the level of pain they experience, such as those with severe arthritis. According to the Centers for Disease Control and Prevention (CDC), 58.5 million people in the United States have arthritis. The Arthritis […]

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Uncategorized Published - 11 August, 2022    By - Dr Clemens
Reduction of Nonoperative Time Using the Induction Room, Parallel Processing, and Sugammadex

AUTHORS: Kaddoum, Roland MD et al  Anesthesia & Analgesia: August 2022 – Volume 135 – Issue 2 – p 406-413 BACKGROUND: An important variable in the operating room is the nonoperative time (NOT), the time between skin closure on a previous case and skin incision on the following case. Mismanagement of NOT can result in significant […]

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Uncategorized Published - 11 August, 2022    By - Dr Clemens
“My Surgical Success”: Feasibility and Impact of a Single-Session Digital Behavioral Pain Medicine Intervention on Pain Intensity, Pain Catastrophizing, and Time to Opioid Cessation After Orthopedic Trauma Surgery

AUTHORS: Ziadni, Maisa S. PhD et al  Anesthesia & Analgesia: August 2022 – Volume 135 – Issue 2 – p 394-405 BACKGROUND: Behavioral pain treatments may improve postsurgical analgesia and recovery; however, effective and scalable options are not widely available. This study tested a digital perioperative behavioral medicine intervention in orthopedic trauma surgery patients for feasibility […]

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Uncategorized Published - 11 August, 2022    By - Dr Clemens
Platelet Transfusion and Outcomes After Massive Transfusion Protocol Activation for Major Trauma

AUTHORS: Aichholz, Pudkrong K. MD et al  Anesthesia & Analgesia: August 2022 – Volume 135 – Issue 2 – p 385-393 BACKGROUND:  Incorporation of massive transfusion protocols (MTPs) into acute major trauma care has reduced hemorrhagic mortality, but the threshold and timing of platelet transfusion in MTP are controversial. This study aimed to describe early (first […]

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Uncategorized Published - 11 August, 2022    By - Dr Clemens
What to know about myofascial pain syndrome

Author: Caitlin Geng MedicalNewsToday Myofascial pain syndrome is a chronic condition that affects the musculoskeletal system, including the bones, tendons, cartilage, ligaments, and connective tissue. The muscular and skeletal systems work together to move and support the body. Musculoskeletal pain affects up to 80% of the population. Myofascial pain syndrome is one of the most common […]

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Uncategorized Published - 11 August, 2022    By - Dr Clemens
Subanesthetic Dose of Propofol Activates the Reward System in Rats

AUTHORS: Nagata, Isao MD et at Anesthesia & Analgesia: August 2022 – Volume 135 – Issue 2 – p 414-426 BACKGROUND: Propofol has addictive properties, even with a single administration, and facilitates dopamine secretion in the nucleus accumbens (NAc). Activation of the dopaminergic circuits of the midbrain reward system, including the ventral tegmental area (VTA) and […]

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Uncategorized Published - 10 August, 2022    By - Dr Clemens
Outlying End-Tidal Carbon Dioxide During General Anesthesia Is Associated With Postoperative Pulmonary Complications

AUTHORS: Akkermans, Annemarie MD, PhD et al  Anesthesia & Analgesia: August 2022 – Volume 135 – Issue 2 – p 341-353 BACKGROUND: Postoperative pulmonary complications (PPCs) occur in up to 33% of patients who undergo noncardiothoracic surgery. Emerging evidence suggests that permissive hypercapnia may reduce the risk of lung injury. We hypothesized that higher intraoperative end-tidal […]

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Uncategorized Published - 10 August, 2022    By - Dr Clemens
Success and Time to Oxygen Delivery for Scalpel-Finger-Cannula and Scalpel-Finger-Bougie Front-of-Neck Access

AUTHORS: Zhang, Jinbin MMED et al  Anesthesia & Analgesia: August 2022 – Volume 135 – Issue 2 – p 376-384 BACKGROUND: Emergency front-of-neck access (FONA) is particularly challenging with impalpable neck anatomy. We compared 2 techniques that are based on a vertical midline neck incision, followed by finger dissection and then either a cannula or scalpel […]

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