Author: Dr Clemens

Uncategorized Published - 17 February, 2023    By - Dr Clemens
Cerebral metabolic derangements following traumatic brain injury

Authors: Demers-Marcil, Simona,b; Coles, Jonathan P.a Anaesthesiology 35(5):p 562-569, October 2022.  Summary Mitochondrial dysfunction and the use of alternative energy substrates are potential therapeutic targets, but improved understanding of the causes, impact and significance of metabolic derangements in clinical TBI are needed. Maintaining adequate oxygen and glucose delivery across the injured brain may accelerate the […]

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Uncategorized Published - 17 February, 2023    By - Dr Clemens
A novel barrier device and method for protection against airborne pathogens during endotracheal intubation

Authors: Alonso, Julio M.; Lipman, Jeffrey; Shekar, Kiran European Journal of Anaesthesiology 39(11):p 900-903, November 2022.  Editor, Healthcare professionals involved in aerosol-generating procedures, such as endotracheal intubation are at high risk of exposure to respiratory pathogens, such as SARS-CoV-2,1,2 despite current preventive measures including personal protective equipment.3 Past attempts to mitigate the risk of exposure to aerosols […]

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Uncategorized Published - 17 February, 2023    By - Dr Clemens
Anesthesia Care for Patients With Limited English Proficiency

Authors: Harrison Charwat, MD; Meghan Lane-Fall, MD, MSHP, FCCM Anesthesia Patient Safety Foundation Volume 38, No. 1 • February 2023  Language barriers in health care are not benign, and they contribute to disparities in care and outcomes for patients who do not speak English well as compared to English-speaking patients. Individuals with “limited English proficiency” (LEP) […]

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Uncategorized Published - 17 February, 2023    By - Dr Clemens
Level of Evidence of Guidelines for Perioperative Management of Patients With Obstructive Sleep Apnea

Authors: Singh, Mandeep MD, MSc, FRCPC et al Anesthesia & Analgesia 136(2):p 262-269, February 2023. Abstract Currently, the quality of guidelines for the perioperative management of patients with obstructive sleep apnea (OSA) is unknown, leaving anesthesiologists to make perioperative management decisions with some degree of uncertainty. This study evaluated the quality of clinical practice guidelines regarding […]

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Uncategorized Published - 17 February, 2023    By - Dr Clemens
A Mouse Model of Spinal Cord Hypoperfusion with Immediate Paralysis Caused by Endovascular Repair of Thoracic Aortic Aneurysm

Authors: Hesham Kelani, M.D. et al  Anesthesiology January 2023. Background A clinically relevant mouse model of thoracic endovascular aortic repair-induced ischemic spinal cord injury has been lacking since the procedure was first employed in 1991. We hypothesized that ligation of mouse intercostal arteries would simulate thoracic endovascular aortic repair-induced ischemic spinal cord injury and behavioral […]

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Uncategorized Published - 16 February, 2023    By - Dr Clemens
Obstructive Sleep Apnea Among Gravidas With Chronic Hypertension Compared to Matched Controls

AUTHORS: Dominguez, Jennifer E. MD, MHS et al  Anesthesia & Analgesia 136(2):p 205-214, February 2023. BACKGROUND: Previous studies of obstructive sleep apnea (OSA) risk in gravidas with chronic hypertension (cHTN) did not control for obesity as a risk factor for OSA. We therefore performed this study to evaluate whether OSA is more prevalent among gravidas with […]

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Uncategorized Published - 16 February, 2023    By - Dr Clemens
Combined Arterial Hypertension and Ischemic Stroke Exaggerate Anesthesia-Related Hypotension and Cerebral Oxygenation Deficits

Authors: Zhang, Tracy MD et al  Anesthesia & Analgesia November 09, 2022. Background: Intraoperative arterial hypotension (IOH) is a common side effect of general anesthesia (GA), associated with poor outcomes in ischemic stroke. While IOH is more prevalent with hypertension, it is unknown whether IOH may differ when GA is induced during ischemic stroke, versus […]

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Uncategorized Published - 16 February, 2023    By - Dr Clemens
Multimodal Analgesic for Knee Arthroplasty: Comment

Authors: Qiuru Wang, M.D. et al Anesthesiology January 2023. To the Editor: We read with great interest the article by Felipe Muñoz-Leyva et al.  entitled “No Benefits of Adding Dexmedetomidine, Ketamine, Dexamethasone, and Nerve Blocks to an Established Multimodal Analgesic Regimen after Total Knee Arthroplasty” published in the July 2022 issue of Anesthesiology. We appreciate the authors’ great […]

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Uncategorized Published - 16 February, 2023    By - Dr Clemens
2023 President’s Report: The Continued Quest “that no one shall be harmed by anesthesia care”

Author: Dan Cole, MD Anesthesia Patent Safety Foundations Volume 38, No. 1 • February 2023  I don’t need to tell anyone reading this article that it has been quite a year in health care. With an environment defined by political polarization and its intersection with COVID, health and health care disparities, tenuous health care economics, burnout, […]

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Uncategorized Published - 16 February, 2023    By - Dr Clemens
Modulation of Cerebral Function by Muscle Afferent Activity, with Reference to Intravenous Succinylcholine

Author: William L. Lanier, M.D. Anesthesiology February 2023, Vol. 138, 209–215. Cerebral Function and Muscle Afferent Activity Following Intravenous Succinylcholine in Dogs Anesthetized with Halothane: The Effects of Pretreatment with a Defasciculating Dose of Pancuronium. By WL Lanier, PA Iaizzo, and JH Milde. Anesthesiology 1989; 71:87–95. Reprinted with permission.By the mid-1980s, it was widely assumed that if […]

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