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AUTHORS: Feng, Yan MD et al Anesthesia & Analgesia December 01, 2022. BACKGROUND: Etomidate-induced myoclonus, a seizure-like movement, is of interest to anesthetists. However, its origin in the brain and its underlying mechanism remain unclear. METHODS: Adult male Sprague-Dawley rats were anesthetized with etomidate, propofol, or lidocaine plus etomidate. We assessed the incidence of myoclonus, […]
Read MoreAUTHORS: van den Bosch et al Anesthesia & Analgesia 135(6):p 1172-1179, December 2022 BACKGROUND: Extracorporeal membrane oxygenation (ECMO) is increasingly used in patients with severe cardiorespiratory collapse. Although prior large database reviews of ECMO use in the peripartum population exist, they do not stratify by ECMO indication nor do they include obstetric conditions such as preeclampsia. […]
Read MoreDG Journal Club AUTHORS: Celaleddin Bildik, Tuna Pehlivanoglu J Shoulder Elbow Surg. 2022 Nov 17 BACKGROUND Tranexamic acid (TXA) was widely used in orthopedic surgery with the aim to reduce intra-/postoperative bleeding and bleeding related complications. The aim of the present study was to assess, whether intra-articular use of TXA during arthroscopic rotator cuff tear […]
Read MoreAUTHORS: Xu, Biao PhD et al Anesthesia & Analgesia 136(2):p 373-386, February 2023. BACKGROUND: Increasing attention has been attracted to the development of bifunctional compounds to minimize the side effects of opioid analgesics. Pharmacological studies have verified the functional interaction between opioid and cannabinoid systems in pain management, suggesting that coactivation of the opioid and cannabinoid […]
Read MoreAUTHORS: Weiss, Raphael MD et al Anesthesia & Analgesia November 29, 2022. BACKGROUND: Acute kidney injury (AKI) is a common complication after cardiac surgery and is associated with increased morbidity and mortality. However, no specific treatment options are available, emphasizing the need for preventive measures. The aim of this study was to clarify the effect […]
Read MoreAUTHORS: Siddiqui, Shahla MD, MSc, FCCM et al Anesthesia & Analgesia December 01, 2022. BACKGROUND: Patient-centered care is increasing in importance especially in the post-coronavirus disease 2019 (COVID-19) pandemic era. We sought to understand factors affecting compassionate care faced by intensivists in the intensive care unit (ICU). METHODS: Using survey methodology incorporating 3 real-life case vignettes, […]
Read MoreAuthors: Dohlman, Lena E et al Current Opinion in Anaesthesiology 35(5):p 647-653, October 2022. Purpose of review Perioperative anesthesia-related mortality is significantly higher in low-resource compared to high-resource countries. Regional anesthesia techniques can provide safety, cost, and access benefits when compared to general anesthesia in these settings but is underutilized primarily due to a lack of […]
Read MoreDG Journal Club AUTHORS: Mario Gómez Duque, Ronald Medina, Cesar Enciso, Edgar Beltran Respir Care. 2022 Nov 22 BACKGROUND Sedation in intensive care is fundamental for optimizing clinical outcomes. For many years the world has been facing high rates of opioid use, and to combat the increasing opioid addiction plans at both national and international […]
Read MoreAUTHORS: Gong, Selena BhSc et al Anesthesia & Analgesia 136(2):p 251-261, February 2023. Abstract BACKGROUND: Several frailty screening tools have been shown to predict mortality and complications after surgery. However, these tools were developed for in-person evaluation and cannot be used during virtual assessments before surgery. The FRAIL (fatigue, resistance, ambulation, illness, and loss of weight) […]
Read MoreAUTHORS: Zhong, John W. MD et al Anesthesia & Analgesia November 29, 2022. BACKGROUND: The nasopharynx is an easily accessible core-temperature monitoring site, but insufficient or excessive nasopharyngeal probe insertion can underestimate core temperature. Our goal was to estimate optimal nasopharyngeal probe insertion depth as a function of age. METHODS: We enrolled 157 pediatric patients […]
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