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AUTHORS: Bradley, Stephanie MD, MPH et al Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 944-953 BACKGROUND: Cardiac valvular disease affects millions of people worldwide and is a major cause of morbidity and mortality. Female patients have been shown to experience inferior clinical outcomes after nonvalvular cardiac surgery, but recent data […]
Read MoreAUTHORS: Truong, Tien M. PharmD, PhD et al Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 929-940 BACKGROUND: Pharmacogenomics, which offers a potential means by which to inform prescribing and avoid adverse drug reactions, has gained increasing consideration in other medical settings but has not been broadly evaluated during perioperative care. […]
Read MoreAuthor: Vetter, Thomas R. MD, MPH Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 900-902 “Those who cannot remember the past are condemned to repeat it.” —Jorge Agustín Nicolás Ruiz de Santayana y Borrás, known in English as George Santayana (1863–1952), Spanish-American philosopher, essayist, poet, and novelist In early January […]
Read MoreAUTHORS: Infanger, Lukas MD et al Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 1031-1040 BACKGROUND: Viscoelastically guided coagulation factor concentrate-based algorithms for the treatment of trauma-induced coagulopathy include the administration of prothrombin complex concentrates (PCCs). However, the exact role of PCC preparations in this context is a matter of debate. […]
Read MoreAUTHORS: Leonard E Estephan et al Laryngoscope. 2022 Oct 14 OBJECTIVE Specific guidelines regarding an optimal general anesthesia (GA) approach to obstructive sleep apnea (OSA) patients remain undefined. Literature comparing the efficacy of total intravenous anesthesia (TIVA) and inhalational anesthesia in this population is sparse. We hypothesize that OSA patients receiving TIVA will experience reduced […]
Read MoreDG Journal Club AUTHORS: Xiaoyan Li, Bei An, Bailin Jiang, Shuai Xu Medicine (Baltimore). 2022 Oct 14; 101(41): e31139 Spinal abnormality surgery, including surgery for ankylosing spondylitis and idiopathic scoliosis, can present significant challenges to anesthesiologists because of the potential difficult airway. The bedside screening tests routinely used to detect difficult airways are highly variable. […]
Read MoreDG Journal Club AUTHORS: Jianming Yue, Leng Zhou, Peng Liang Anaesth Intensive Care. 2022 Oct 10 Upper airway compression is one of the clinical manifestations of thoracic aortic aneurysm, which is associated with poor prognosis and high mortality. A 44-year-old patient with ascending aortic and arch aneurysm who was scheduled for Bentall surgery and total […]
Read MoreAuthors: G. Brock-Utne et al Anesthesiology September 2022. Physician training requires the highest intelligence quotient of all professions to assimilate the vast amounts of complex knowledge required. The most critical decision-making medical specialty is anesthesiology, which requires much art of practicing medicine. That art is acquired via experience from years of medical practice. Clinical experience can also be gleaned from studying […]
Read MoreAuthor: Jessica Norris MedicalNewsToday Migraine headaches can be debilitating and difficult to treat. Researchers are still working to discover factors that influence migraine development and the best ways to treat and prevent these headaches. A recent study found that diets high in the B vitamin thiamine were associated with a decreased risk of migraine. Migraine […]
Read MoreAuthors: Julia Plakhotnik, B.Sc. et at Anesthesiology September 2022. Background Long-lasting local anesthetic use for perioperative pain control is limited by possible cardiotoxicity (e.g., arrhythmias and contractile depression), potentially leading to cardiac arrest. Off-target cardiac sodium channel blockade is considered the canonical mechanism behind cardiotoxicity, however, it does not fully explain the observed toxicity variability […]
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