Author: Dr Clemens

Uncategorized Published - 23 November, 2022    By - Dr Clemens
Sugammadex Versus Neostigmine for Recovery of Respiratory Muscle Strength Measured by Ultrasonography in the Postextubation Period

AUTHORS: Huang, Chanyan MD et al  Anesthesia & Analgesia: October 24, 2022 BACKGROUND:  Although sugammadex is well known for its use in reducing the incidence of residual neuromuscular blockade, this has not always been translated to improved clinical measures of postoperative respiratory muscle strength. Expiratory muscles play an important role in airway clearance and inspiratory muscle […]

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Uncategorized Published - 23 November, 2022    By - Dr Clemens
The King’s Three Questions: A Short Story I Want My Teams to Understand

AUTHOR: Luedi, Markus M. MD, MBA Anesthesia & Analgesia: October 2022 – Volume 135 – Issue 4 – p 896-897 Life is not primarily a quest for pleasure, as [Sigmund] Freud believed, or a quest for power, as Alfred Adler taught, but a quest for meaning. The greatest task for any person is to find meaning […]

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Uncategorized Published - 23 November, 2022    By - Dr Clemens
Efficacy of Presurgical Interventions to Promote Smoking Cessation

AUTHORS: Gavilan, Eva MSN et al  Anesthesia & Analgesia: October 24, 2022 Abstract The aim of this study was to evaluate the efficacy of presurgical interventions for promoting smoking cessation in terms of achieving smoking abstinence and reducing surgical complication rates. A systematic review of randomized clinical trials (RCTs) published from March 2009 to April 2021 […]

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Uncategorized Published - 22 November, 2022    By - Dr Clemens
Manually Controlled, Continuous Infusion of Phenylephrine or Norepinephrine for Maintenance of Blood Pressure and Cardiac Output During Spinal Anesthesia for Cesarean Delivery

AUTHORS: Belin, Olivier MD et al  Anesthesia & Analgesia: October 24, 2022 BACKGROUND: To counteract the vasoplegia induced by spinal anesthesia (SA) and maintain blood pressure (BP) during cesarean delivery, phenylephrine is currently recommended, but norepinephrine might offer superior preservation of cardiac output. We aimed to compare the hemodynamic effects of phenylephrine and norepinephrine administered by […]

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Uncategorized Published - 22 November, 2022    By - Dr Clemens
Reactive Oxygen Species Contributes to Type 2 Diabetic Neuropathic Pain via the Thioredoxin-Interacting Protein-NOD–Like Receptor Protein 3-N-Methyl-D-Aspartic Acid Receptor 2B Pathway

AUTHORS: Wang, Jun-Wu BD et al Anesthesia & Analgesia: October 2022 – Volume 135 – Issue 4 – p 865-876 BACKGROUND: The number of patients with diabetic neuropathic pain (DNP) continues to increase, but available treatments are limited. This study aimed to examine the influence of reactive oxygen species (ROS)-thioredoxin-interacting protein (TXNIP)-NOD–like receptor protein 3 (NLRP3)-N-methyl-D-aspartic […]

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Uncategorized Published - 22 November, 2022    By - Dr Clemens
Open Reimplementation of the BIS Algorithms for Depth of Anesthesia

AUTHOR: Connor, Christopher W. MD, PhD Anesthesia & Analgesia: October 2022 – Volume 135 – Issue 4 – p 855-864 BACKGROUND: BIS (a brand of processed electroencephalogram [EEG] depth-of-anesthesia monitor) scores have become interwoven into clinical anesthesia care and research. Yet, the algorithms used by such monitors remain proprietary. We do not actually know what we […]

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Uncategorized Published - 22 November, 2022    By - Dr Clemens
Outcomes and Disposition of Patients After Case Cancellation on Day of Surgery for Reasons Attributed to Medical or Anesthetic Care

AUTHORS: Tewfik, George L. MD et al  Anesthesia & Analgesia: October 2022 – Volume 135 – Issue 4 – p 845-854 BACKGROUND: Many day-of-surgery cancellations are avoidable, and different strategies are used to prevent these costly adverse events. Despite these past analyses and evaluations of positive interventions, studies have not examined the final disposition of patients […]

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Uncategorized Published - 22 November, 2022    By - Dr Clemens
Dexmedetomidine Diminishes, but Does Not Prevent, Developmental Effects of Sevoflurane in Neonatal Rats

AUTHORS: Yang, Zhengbo MD et al  Anesthesia & Analgesia: October 2022 – Volume 135 – Issue 4 – p 877-887 BACKGROUND: Sevoflurane (SEVO) increases neuronal excitation in neonatal rodent brains through alteration of gamma aminobutyric acid (GABA)(A) receptor signaling and increases corticosterone release. These actions may contribute to mechanisms that initiate the anesthetic’s long-term neuroendocrine and […]

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Uncategorized Published - 21 November, 2022    By - Dr Clemens
Single-Shot Lumbar Erector Spinae Plane Block in Total Hip Replacement

AUTHORS: Chan, Anyon MBChB et al  Anesthesia & Analgesia: October 2022 – Volume 135 – Issue 4 – p 829-836 BACKGROUND: Lumbar erector spinae plane block (ESPB) has been proposed to relieve pain after total hip replacement (THR), but high-quality evidence is scarce. METHODS: This double-blinded (patient and assessor) randomized clinical trial, performed in 2 tertiary […]

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Uncategorized Published - 21 November, 2022    By - Dr Clemens
Burnout Syndrome Among Anesthesia Providers Working in Public Hospitals in Rwanda

AUTHORS: Tuyishime, Eugene MBBS, MSc, MMed, FCA (ECSA) et al  Anesthesia & Analgesia: October 2022 – Volume 135 – Issue 4 – p 820-828 BACKGROUND:  Many studies address anesthesia provider burnout in high-income countries; however, there is a paucity of data on burnout for anesthesia providers in low-income countries (LICs). Our objectives were (1) to evaluate […]

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