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AUTHORS: Xu, Biao PhD et al Anesthesia & Analgesia 136(2):p 373-386, February 2023 BACKGROUND: Increasing attention has been attracted to the development of bifunctional compounds to minimize the side effects of opioid analgesics. Pharmacological studies have verified the functional interaction between opioid and cannabinoid systems in pain management, suggesting that coactivation of the opioid and cannabinoid […]
Read MoreAUTHORS: Fleischmann, Antonia MD et al Anesthesia & Analgesia 136(2):p 346-354, February 2023. BACKGROUND: Electroencephalogram (EEG)-based monitors of anesthesia are used to assess patients’ level of sedation and hypnosis as well as to detect burst suppression during surgery. One of these monitors, the Entropy module, uses an algorithm to calculate the burst suppression ratio (BSR) that […]
Read MoreAUTHORS: Olmos, Andrea V. MD et al Anesthesia & Analgesia 136(2):p 327-337, February 2023. BACKGROUND: Volatile anesthetic consumption can be reduced by minimizing excessive fresh gas flows (FGFs). Currently, it is unknown whether decision support tools embedded within commercial electronic health record systems can be successfully adopted to achieve long-term reductions in FGF rates. The authors […]
Read MoreAUTHORS: Cummings Joyner, Alice Kate MS*; King, Michael R. MD†; Safranek, Conrad BS‡; Parvathinathan, Gomathy MS§; De Souza, Elizabeth PhD§; Anderson, T. Anthony PhD, MD§ Anesthesia & Analgesia 136(2):p 317-326, February 2023. BACKGROUND: Prolonged opioid use after surgery (POUS), defined as the filling of at least 1 opioid prescription filled between 90 and 180 days […]
Read MoreAuthors: Holly B. Ende, MD; Jonathan P. Wanderer, MD, MPhil Anesthesia Patient Safety Foundations Volume 38, No. 1 • February 2023 The delivery of safe and effective anesthesia care is grounded in the science of quality improvement, which relies on accurate and timely reporting of patient outcomes. In the era of the electronic health record (EHR) […]
Read MoreAuthors: Jonathan M. Tan, MD, MPH, MBI, FASA; Maxime P. Cannesson, MD, PhD Anesthesia Patient Safety Foundation Volume 38, No. 1 • February 2023 INTRODUCTION Anesthesiology as a specialty has a long history of innovation in technology development linked to improvements in patient safety. However, the speed of technological development in the past 20 years has […]
Read MoreAUTHORS: Alalade, Emmanuel MD et al Anesthesia & Analgesia 136(2):p 308-316, February 2023. BACKGROUND: Chronic opioid use among adolescents is a leading preventable public health problem in the United States. Consequently, a sizable proportion of surgical patients in this age group may have a comorbid opioid use disorder (OUD). No previously published study has examined the […]
Read MoreAUTHORS: Elmi-Sarabi, Mahsa MS et al Anesthesia & Analgesia 136(2):p 282-294, February 2023. BACKGROUND: Pulmonary hypertension (PH) and right ventricular (RV) dysfunction are major complications in cardiac surgery. Intraoperative management of patients at high risk of RV failure should aim to reduce RV afterload and optimize RV filling pressures, while avoiding systemic hypotension, to facilitate weaning […]
Read MoreAuthors: Luke S. Janik, MD; Samantha Stamper, MD; Jeffery S. Vender, MD, MCCM; Christopher A. Troianos, MD, FASE, FASA Anesthesia Patient Safety Foundation Volume 37, No. 3 • October 2022 Reprinted from Anesthesia & Analgesia, June 2022 • Volume 134 • Number 6, pages 1192–1200, with permission from International Anesthesia Research Society. Professional titles and nomenclature were standardized […]
Read MoreAuthors: Shauna Schwartz, DO; Yong G. Peng, MD, PhD, FASE, FASA Anesthesia Patient Safety Foundation Volume 38, No. 1 • February 2023 The information provided is for safety-related educational purposes only, and does not constitute medical or legal advice. Individual or group responses are only commentary, provided for purposes of education or discussion, and are […]
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