Author: Dr Clemens

Uncategorized Published - 27 February, 2023    By - Dr Clemens
Respiratory Effects of Biased Ligand Oliceridine in Older Volunteers: A Pharmacokinetic–Pharmacodynamic Comparison with Morphine 2023

Authors: Pieter Simons, M.D. et al  Anesthesiology March 2023, Vol. 138, 249–263. Background Oliceridine is a G protein–biased µ-opioid, a drug class that is associated with less respiratory depression than nonbiased opioids, such as morphine. The authors quantified the respiratory effects of oliceridine and morphine in elderly volunteers. The authors hypothesized that these opioids differ in […]

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Uncategorized Published - 27 February, 2023    By - Dr Clemens
Comparison of Contralateral Acceleromyography and Electromyography for Posttetanic Count Measurement

Authors: Hyunyoung Joo, M.D. et al  Anesthesiology March 2023, Vol. 138, 241–248. Background Electromyography has advantages over mechanomyography and acceleromyography. Previously, agreement of the train-of-four counts between acceleromyography and electromyography was found to be fair. The objective of this study was to assess the agreement of posttetanic count including agreement of neuromuscular blockade status (intense block, […]

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Uncategorized Published - 24 February, 2023    By - Dr Clemens
Telemedicine for Opioid Use Disorder: A Pandemic Experiment

Author: Avery Hurt Practical Pain Management Vol 23 Issue 1 Feb 2023 Despite an alarming increase in opioid addiction over the past decade, access to treatment for opioid use disorder (OUD) is still limited. Medications including methadone, naltrexone, and buprenorphine have proved beneficial for OUD treatment, however, fewer than 30% of people who need treatment […]

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Uncategorized Published - 24 February, 2023    By - Dr Clemens
Predicting Intensive Care Delirium with Machine Learning: Model Development and External Validation

Authors: Kirby D. Gong, M.S.E. et al  Anesthesiology March 2023, Vol. 138, 299–311. Background Delirium poses significant risks to patients, but countermeasures can be taken to mitigate negative outcomes. Accurately forecasting delirium in intensive care unit (ICU) patients could guide proactive intervention. Our primary objective was to predict ICU delirium by applying machine learning to clinical […]

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Uncategorized Published - 24 February, 2023    By - Dr Clemens
Anesthesia Incident Reporting System (AIRS) Case 2022-12: Knowledge is Power, But How to Keep Up?

ASA Monitor December 2022, Vol. 86, 19–20. A 76-year-old male was found to have multiple episodes of ventricular tachycardia at a community hospital. He was started on a lidocaine infusion and transferred to a tertiary care hospital for an emergent cardiac ablation. Previous medical history included congestive heart failure secondary to non-ischemic cardiomyopathy with an ejection […]

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Uncategorized Published - 24 February, 2023    By - Dr Clemens
Managing Long COVID Syndrome

Author: Thanthullu Vasu M.B.B.S., M.D., D.N.B., F.R.C.A., F.F.P.M.R.C.A., tfm Publishing Limited 2022  Pages: 310. ISBN-13: 978-1913755201. ISBN-10: 1913755207. Price: $32.49. Anesthesiology February 2023. The textbook titled Managing Long COVID Syndrome is an educational and tractable reference for not only medical providers, but also the general public. This is one of the first texts dedicated to long COVID […]

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Uncategorized Published - 24 February, 2023    By - Dr Clemens
Analgesic Effectiveness and Dorsal Root Ganglia Protein Modulation of a Peripheral Adenosine Monophosphate Kinase Alpha Activator (O304) Following Lumbar Disk Puncture in the Mouse

AUTHORS: Das, Vaskar PhD et al  Anesthesia & Analgesia 135(6):p 1293-1303, December 2022. BACKGROUND: Disk herniation is a primary cause of radicular back pain. The purpose of this study was to evaluate the antiallodynic effective dose in 50% of the sample (ED50) and dorsal root ganglion (DRG) protein modulation of a peripheral direct adenosine monophosphate kinase […]

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Uncategorized Published - 23 February, 2023    By - Dr Clemens
Performance of Noninvasive Airway Occlusion Maneuvers to Assess Lung Stress and Diaphragm Effort in Mechanically Ventilated Critically Ill Patients

Authors: Heder J. de Vries, M.D. et al  Anesthesiology March 2023, Vol. 138, 274–288. Background Monitoring and controlling lung stress and diaphragm effort has been hypothesized to limit lung injury and diaphragm injury. The occluded inspiratory airway pressure (Pocc) and the airway occlusion pressure at 100 ms (P0.1) have been used as noninvasive methods to assess […]

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Uncategorized Published - 23 February, 2023    By - Dr Clemens
Is time running out for small ASCs?

Author: Patsy Newitt  Becker’s ASC Review Although the ASC industry remains fragmented, some leaders are worried about the viability of independent ASCs amid an increasingly consolidated healthcare landscape. “I am focused on the consolidation of health systems, capital equity firms, private practices and third-party payers purchasing practices and ASCs,” Matt Kraemer, administrator of Northern Arizona […]

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Uncategorized Published - 23 February, 2023    By - Dr Clemens
Hospital-, Anesthesiologist-, Surgeon-, and Patient-Level Variations in Neuraxial Anesthesia Use for Lower Limb Revascularization Surgery

AUTHORS: Roberts, Derek J. MD, PhD, FRCSC et al  Anesthesia & Analgesia 135(6):p 1282-1292, December 2022. BACKGROUND: Although neuraxial anesthesia may promote improved outcomes for patients undergoing lower limb revascularization surgery, its use is decreasing over time. Our objective was to estimate variation in neuraxial (versus general) anesthesia use for lower limb revascularization at the hospital, […]

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