Author: Dr Clemens

Uncategorized Published - 2 August, 2023    By - Dr Clemens
The Effect of Night Float Rotation on Resident Sleep, Activity, and Well-Being

AUTHORS: Ruan, Alexandra MD et al  Anesthesia & Analgesia 136(4):p 701-710, April 2023. Background: Night float call systems are becoming increasingly common at training programs with the goal of reducing fatigue related to sleep deprivation and sleep disturbance. Previous studies have shown that trainees obtain less sleep during the night float rotation and have decreased sleep […]

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Uncategorized Published - 2 August, 2023    By - Dr Clemens
Influence of Different Sevoflurane Concentrations on Postoperative Cognitive Function in Aged Rats

AUTHORS: Yamamoto, Natsuko MD et al  Anesthesia & Analgesia 136(4):p 772-778, April 2023. BACKGROUND: Postoperative cognitive dysfunction may be associated with neuroinflammation, and sevoflurane suppresses surgery-induced inflammation. We hypothesized that low concentrations of sevoflurane would result in more impaired postoperative cognitive function compared to high concentrations. METHODS: Aged male Sprague–Dawley rats (n = 21, 17–22 months) […]

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Uncategorized Published - 1 August, 2023    By - Dr Clemens
Postoperative Risk of Transfusion After Reversal of Residual Neuromuscular Block With Sugammadex Versus Neostigmine

AUTHORS: Schmidt, Marc T. et al Anesthesia & Analgesia 136(4):p 745-752, April 2023. BACKGROUND: Sugammadex and neostigmine are routinely used to reverse residual neuromuscular blocks at the end of surgery. Sugammadex has been linked with prolongation of laboratory coagulation markers, but clinical relevance on postoperative blood loss and transfusions remains unclear. METHODS: In this retrospective, single-center, […]

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Uncategorized Published - 1 August, 2023    By - Dr Clemens
Maternal Cardiovascular Morbidity Events Following Preeclampsia

AUTHORS: Meng, Marie-Louise MD et al Anesthesia & Analgesia 136(4):p 728-737, April 2023. BACKGROUND: Patients with preeclampsia are at high risk for long-term cardiovascular events, yet the short-term, acute cardiovascular complications that follow preeclampsia are understudied. The objective of this study was to compare the short-term, acute maternal cardiovascular morbidity events after delivery among patients with […]

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Uncategorized Published - 1 August, 2023    By - Dr Clemens
Association Between Age- and Sex-Specific Body Mass Index Percentile and Multiple Intubation Attempts

AUTHORS: Chhabada, Surendrasingh MD et al  Anesthesia & Analgesia March 15, 2023. BACKGROUND: Obesity distorts airways and slightly complicates intubations in adults, but whether obesity complicates pediatric intubations remains unclear. We, therefore, tested the primary hypothesis that increasing age- and sex-specific body mass index (BMI) percentile is associated with difficult intubation, defined as >1 intubation […]

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Uncategorized Published - 1 August, 2023    By - Dr Clemens
Mechanically Ventilated Patients With Coronavirus Disease 2019 Had a Higher Chance of In-Hospital Death If Treated With High-Flow Nasal Cannula Oxygen Before Intubation

AUTHORS: Nurok, Michael MBChB, PhD et al  Anesthesia & Analgesia 136(4):p 692-698, April 2023. BACKGROUND: The impact of high-flow nasal cannula (HFNC) on outcomes of patients with respiratory failure from coronavirus disease 2019 (COVID-19) is unknown. We sought to assess whether exposure to HFNC before intubation was associated with successful extubation and in-hospital mortality compared to […]

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Uncategorized Published - 1 August, 2023    By - Dr Clemens
Labor Neuraxial Analgesia and Its Association With Perinatal Outcomes in China in 2015–2016

AUTHORS: Meng, Xi MS et al   Anesthesia & Analgesia March 07, 2023.  BACKGROUND: The use of labor neuraxial analgesia (NA) in China has increased significantly in the past decade, and the current rate of use is unknown. This study aimed to describe the epidemiology of NA based on a large multicenter cross-sectional survey, the China […]

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Uncategorized Published - 31 July, 2023    By - Dr Clemens
Perioperative Iron Deficiency in Patients Scheduled for Major Elective Surgeries

AUTHORS: Capdevila, Xavier MD, PhD et al Anesthesia & Analgesia 137(2):p 322-331, August 2023. BACKGROUND: The management of perioperative iron deficiency is a component of the concept of patient blood management. The objective of this study was to update French data on the prevalence of iron deficiency in patients scheduled for major surgery. METHODS: The CARENFER […]

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Uncategorized Published - 31 July, 2023    By - Dr Clemens
Age-Dependent Electroencephalogram Features in Infants Under Spinal Anesthesia Appear to Mirror Physiologic Sleep in the Developing Brain

AUTHORS: Santa Cruz Mercado et al  Anesthesia & Analgesia March 07, 2023. BACKGROUND: Infants under spinal anesthesia appear to be sedated despite the absence of systemic sedative medications. In this prospective observational study, we investigated the electroencephalogram (EEG) of infants under spinal anesthesia and hypothesized that we would observe EEG features similar to those seen […]

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Uncategorized Published - 31 July, 2023    By - Dr Clemens
Indoleamine 2,3-Dioxygenase Deletion to Modulate Kynurenine Pathway and to Prevent Brain Injury After Cardiac Arrest in Mice

Authors: Aurora Magliocca, MD, PhD et al  Anesthesiology July 2023. Background The catabolism of the essential amino acid tryptophan to kynurenine is emerging as a potential key pathway involved in post-cardiac arrest brain injury. The aim of this study was to evaluate the effects of the modulation of kynurenine pathway on cardiac arrest outcome, through […]

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