DG Journal Club Chailee Moss, Prerna R Pandya, Lisa Yanek, David Lovejoy Int Urogynecol J. 2022 Dec 21 INTRODUCTION AND HYPOTHESIS Despite the prevalence of anxiety, its impact on postoperative pain remains poorly characterized. The present study was aimed at assessing the impact of preoperative anxiety on postoperative pain in patients undergoing pelvic reconstructive surgery. We […]
Read MoreDG Journal Club Åsa Henning Waldum, Mirjam Lukasse, Anne Cathrine Staff, Ragnhild Sørum Falk Birth. 2022 Dec 18 BACKGROUND A negative childbirth experience has short- and long-term consequences for both mother and child. This study aimed to investigate the association between intrapartum pudendal nerve block (PNB) analgesia and childbirth experience. METHODS Primiparous women with a singleton […]
Read MoreAUTHORS: Dillon, Simon T. PhD et al BACKGROUND: The neuroinflammatory response to surgery can be characterized by peripheral acute plasma protein changes in blood, but corresponding, persisting alterations in cerebrospinal fluid (CSF) proteins remain mostly unknown. Using the SOMAscan assay, we define acute and longer-term proteome changes associated with surgery in plasma and CSF. We […]
Read MoreAUTHORS: Guay, Christian S. MD et al Anesthesia & Analgesia 136(1):p 140-151, January 2023. BACKGROUND: Delirium is an acute syndrome characterized by inattention, disorganized thinking, and an altered level of consciousness. A reliable biomarker for tracking delirium does not exist, but oscillations in the electroencephalogram (EEG) could address this need. We evaluated whether the frequencies of […]
Read MoreAUTHORS: Ragheb, Jacqueline MD et al Anesthesia & Analgesia 136(1):p 130-139, January 2023. BACKGROUND: Delirium is the most common postoperative complication in older adults, though anesthesiologist awareness of delirium prevention guidelines—and associated practice trends—remains unknown. METHODS: This was a convergent mixed-methods study, which simultaneously analyzed quantitative and qualitative data to determine delirium guideline awareness among anesthesiologists […]
Read MoreAUTHORS: Tanaka, Kenichi A. MD, MSc et al Anesthesia & Analgesia 136(1):p 123-129, January 2023. BACKGROUND: Increased body mass index (BMI) is considered as an important factor that affects the need for total knee and hip arthroplasty (TKA/THA) and the rate of perioperative complications. Previous investigations have not fully established the relationship of BMI and perioperative […]
Read MoreAUTHORS: Hofer, Ira S. MD et al Anesthesia & Analgesia 136(1):p 111-122, January 2023. BACKGROUND: A single laboratory range for all individuals may fail to take into account underlying physiologic differences based on sex and genetic factors. We hypothesized that laboratory distributions differ based on self-reported sex and ethnicity and that ranges stratified by these factors […]
Read MoreAUTHORS: Chambrin, Coralie MD et al Anesthesia & Analgesia 136(1):p 101-110, January 2023. BACKGROUND: Inhaled halogenated anesthetics are responsible for half of operating room total greenhouse gas emissions. Sustainable anesthesia groups were set up in 4 Lyon, France, university hospitals (Hospices Civils de Lyon) in January 2018 and have supported a specific information campaign about the […]
Read MoreAUTHORS: Lyu, Wenyuan MD et al Anesthesia & Analgesia 136(1):p 94-100, January 2023. BACKGROUND: Norepinephrine is effective in preventing spinal hypotension during cesarean birth; however, an optimal regimen has not been determined. We hypothesized that an initial bolus of norepinephrine improves efficacy of spinal hypotension prophylaxis beyond continuous norepinephrine alone. METHODS: In this double-blind, controlled study, […]
Read MoreAUTHORS: Lee, Linden O. MD et al Anesthesia & Analgesia 136(1):p 86-93, January 2023. BACKGROUND: Previous studies have suggested that administration of epidural 3% 2-chloroprocaine (CP) before epidural morphine results in decreased analgesic efficacy of epidural morphine. We sought to determine whether these observations were a result of antagonism or a window period between the conclusion […]
Read More