Authors: Dragovic SZ et al. Anesthesia & Analgesia, Volume 142, Issue 2, pages 249–260, February 2026 Summary:This retrospective study examines whether commonly used processed EEG metrics obscure meaningful differences between anesthetic agents, particularly propofol versus volatile fluranes (sevoflurane and desflurane). The authors challenge the “one-size-fits-all” assumption that equivalent processed EEG targets reflect comparable anesthetic brain […]
Read MoreAuthors: Kong H et al. Journal: Anesthesiology, November 25, 2025. DOI: 10.1097/ALN.0000000000005778 SummaryThis randomized, double-blind, placebo-controlled trial evaluated whether preemptive magnesium sulfate infusion improves intraoperative hemodynamic stability during pheochromocytoma and paraganglioma (PPGL) resection—procedures well known for extreme catecholamine-mediated blood pressure and heart rate fluctuations. Ninety-two patients scheduled for PPGL resection were randomized to receive either […]
Read MoreAuthor: Sophie Eydis Becker’s ASC Review Anesthesiology saw a year of significant innovation in 2025 as new technologies, techniques and care models redefined what is possible in the perioperative environment. From AI-driven automation to next-generation pain control, five breakthroughs in particular helped shape the specialty. 1. AI-driven decision support, smart ultrasound and virtual reality-enhanced training […]
Read MoreAuthors: Kwon H-M et al. Journal: Anesthesiology, December 2, 2025. DOI: 10.1097/ALN.0000000000005747 SummaryThis retrospective registry-based study evaluated whether incorporating cardiac biomarkers into existing risk models improves prediction of post–liver transplant mortality in patients with acute-on-chronic liver failure (ACLF). Cardiovascular complications are the leading cause of death after liver transplantation in this population, yet commonly used […]
Read MoreAuthors: Turan A et al. Journal: Anesthesiology, December 1, 2025. DOI: 10.1097/ALN.0000000000005869 SummaryThis multicenter randomized controlled trial (the CLEVELAND Trial) evaluated whether liposomal bupivacaine provides superior or prolonged analgesia compared with plain bupivacaine or saline when used in single-injection, four-quadrant transversus abdominis plane (TAP) blocks for major abdominal surgery. Given widespread use of liposomal bupivacaine […]
Read MoreAuthors: Hussain N et al. Journal: Anesthesiology, December 1, 2025. DOI: 10.1097/ALN.0000000000005876 SummaryThis systematic review evaluated the statistical robustness of randomized controlled trials assessing spinal cord stimulation (SCS for chronic pain using the fragility index (FI). While SCS has gained wide adoption based on statistically significant trial outcomes, the fragility index provides a complementary lens […]
Read MoreAuthors: Tong L et al. Journal: Anesthesiology, December 15, 2025. DOI: 10.1097/ALN.0000000000005903 SummaryThis preclinical study investigated the role of glutamatergic neurons in the dorsomedial periaqueductal gray (dmPAG) as a shared neural substrate regulating arousal and emergence across multiple general anesthetics. Although general anesthetics differ in molecular targets, the authors hypothesized that convergent brainstem circuitry may […]
Read MoreAuthor: Molly Gamble Becker’s Hospital Review Seven hundred fifty-six rural U.S. hospitals are at risk of closure due to financial problems, with more than 40% of those hospitals at immediate risk of closure. The counts are drawn from the Center for Healthcare Quality and Payment Reform’s most recent analysis, based on hospitals’ latest cost reports submitted […]
Read MoreAuthors: Wachtendorf LJ et al. Journal: Anesthesiology, December 4, 2025. DOI: 10.1097/ALN.0000000000005880 SummaryThis large retrospective cohort study evaluated how the introduction of sugammadex influenced intraoperative rocuronium dosing practices and whether these changes affected postoperative respiratory complications. Because sugammadex enables rapid reversal of even deep neuromuscular blockade, concerns have emerged that its availability may encourage higher […]
Read MoreAuthor: Francesca Mathewes Becker’s ASC Review Workforce shortages, reimbursement declines and costly inefficiencies were some of the biggest anesthesia-related issues for ASC leaders in 2025. While many of these issues will persist into 2026, here are the wins that ASC leaders shared with Becker’s throughout the last year: Staffing shortages The projected shortage of anesthesiologists by […]
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