Author: Dr Clemens

Uncategorized Published - 30 May, 2023    By - Dr Clemens
Deep Isoflurane Anesthesia Is Associated with Alterations in Ion Homeostasis and Specific Na+/K+-ATPase Impairment in the Rat Brain 2023

Authors: Clemens Reiffurth, Ph.D. et al  Anesthesiology June 2023, Vol. 138, 611–623. Background Maintenance of ion homeostasis is essential for normal brain function. Inhalational anesthetics are known to act on various receptors, but their effects on ion homeostatic systems, such as sodium/potassium-adenosine triphosphatase (Na+/K+-ATPase), remain largely unexplored. Based on reports demonstrating global network activity and wakefulness […]

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Uncategorized Published - 30 May, 2023    By - Dr Clemens
Chronic Pain at the Pharmacy: Methadone Initiation for CRPS and Comorbidities

Author: Amarquaye W. Pract Pain Manag. 2023 May/June;23(3). When a patient asks about beginning methadone therapy for CRPS, clinical pharmacist William Amarquaye advises on administration, titration, side effects, and interactions. Patient Scenario: Patient Prescribed Methadone for CRPS The Patient Patient Bob* called our pharmacy inquiring about a new prescription for methadone that he was placed […]

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Uncategorized Published - 29 May, 2023    By - Dr Clemens
Happy Memorial Day

Happy Memorial Day! May we never forget those who made the ultimate sacrifice for our freedom. Enjoy the day with your loved ones, and don’t forget to think about those who served and sacrificed. Happy Memorial Day!

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Uncategorized Published - 26 May, 2023    By - Dr Clemens
Attributable perioperative cost of frailty after major, elective non-cardiac surgery 2023

Authors: Ryan McGinn, MD MSc et al  Anesthesiology May 2023. Background Patients with frailty consistently experience higher rates of perioperative morbidity and mortality; however, costs attributable to frailty remain poorly defined. We sought to identify older patients with and without frailty using a validated, multidimensional frailty index and estimated the attributable costs in the year […]

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Uncategorized Published - 26 May, 2023    By - Dr Clemens
Assessing Potentially Modifiable Factors Associated with the Development of Postoperative Delirium

Authors: Jeanna D. Blitz, MD, FASA et al  ASA Monitor March 2023, Vol. 87, 27–28. Brain health is inextricably linked with overall physical health. Evidence for the mind-body connection and the bi-directional relationship between them continues to emerge. The past decade has also seen the emergence of a focus on multifactorial quality and outcomes metrics within […]

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Uncategorized Published - 26 May, 2023    By - Dr Clemens
Beers Criteria Medications: To Give or Not Give 2023

Authors: Michelle L. Humeidan, MD, PhD; Daniel J. Cole, MD, FASA ASA Monitor November 2022, Vol. 86, 1–6. Life is most delightful when it is on the downward slope, but has not yet reached the abrupt decline. – Seneca We have all encountered geriatric patients amid or on the precipice of an “abrupt decline” in health. Our […]

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Uncategorized Published - 26 May, 2023    By - Dr Clemens
Achieving Age-Friendly Health Care in an Outpatient Perioperative Clinic

Authors: Heather Lander, MD et al  ASA Monitor January 2023, Vol. 87, 20–21. According to a recent World Health Organization (WHO) publication, in 2020 the number of people aged 60 years and older outnumbered children younger than 5 years worldwide (asamonitor.pub/3NC2L83). Simultaneous to the rapidly growing older population, their surgical and perioperative needs are also increasing. […]

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Uncategorized Published - 26 May, 2023    By - Dr Clemens
Hormones May Play a Role in Women’s Migraines 2023

Author: Heidi Splete Practical Pain Management May 15, 2023 Migraine headaches are approximately three times more common in women than in men, but the prevalence of migraine in women decreases after menopause, suggesting a role for sex hormones in migraine development, wrote Bianca Raffaelli, MD, of Charité-Universitätsmedizin Berlin, Germany, and colleagues. In their new study, […]

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Uncategorized Published - 25 May, 2023    By - Dr Clemens
Postoperative Transfusions following Administration of Delayed Cold Stored Platelets vs. Room Temperature Platelets in Cardiac Surgery 2023

Authors: Allan M. Klompas, MBBCh et al Anesthesiology May 2023. Background Delayed cold-storage of room temperature platelets may extend shelflife from 5 to 14 days. We hypothesized the use of delayed cold-stored platelets in cardiac surgery would be associated with decreased postoperative platelet count increments but similar transfusion and clinical outcomes compared to room temperatuve […]

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Uncategorized Published - 25 May, 2023    By - Dr Clemens
Best Practice Alerts Informed by Inpatient Opioid Intake to Reduce Opioid Prescribing After Surgery (PRIOR) 2023

Authors: Megan L. Rolfzen, M.D. et al  Anesthesiology May 2023. Background Over-prescription of opioids after surgery remains common. Residual and unnecessarily prescribed opioids can provide a reservoir for nonmedical use. We therefore tested the hypothesis that a decision-support tool embedded in electronic health records guides clinicians to prescribe fewer opioids at discharge after inpatient surgery. […]

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