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Authors: Bu-Fan Kan, M.D. et al Anesthesiology December 2023. Background The role of Nerve growth factor (NGF)/tyrosine kinase A receptor (TrKA) signaling, which is activated in a variety of pain states, in regulating membrane-associated δ-opioid receptor (mDOR) expression is poorly understood. We hypothesized that elevated NGF in bone cancer tumors could upregulate mDOR expression in […]
Read MoreAuthor: Kelly Wolfgang ASA Monitor January 2024, Vol. 88, 30. Edwards Acumen hypotension predictive index software. “In the last decade, there has been renewed interest in predicting, real-time intervention, and optimization of hemodynamics in the OR and ICU setting for anesthesia and postoperative care,” said Kurosh Takhtehchian, DO, Associate Clinical Professor of Anesthesiology at University of […]
Read MoreRadius Anesthesia Dec 28, 2023 Older individuals contemplating surgery often express concerns regarding potential complications, returning home, and the anticipated improvement in their quality of life. Notably, the avoidance of new or worsening disability becomes a paramount consideration with advancing age. To better guide patients, clinicians must not only discuss surgical success rates but also […]
Read MoreAuthors: Connor T. A. Brenna, MD et al ASA Monitor January 2024, Vol. 88, 1–10. Anesthesiologists now find themselves – perhaps unexpectedly – at a new frontier of brain health: the treatment of neuropsychiatric disorders. Historically, our involvement with mental health has been limited to providing anesthesia care for electroconvulsive therapy, and our focus on brain […]
Read MoreBiosimilar drug treatment for inflammatory disease Wezlana (ustekinumab-auub) has received U.S. Food and Drug Administration (FDA) approval as a biosimilar and interchangeable medication with Stelara (ustekinumab), a drug used in the treatment of various inflammatory diseases. Wezlana is now authorized to treat a range of conditions in both adult and pediatric patients, including moderate to […]
Read MoreAuthor: Jeffrey J. Bettinger, PharmD MedCentral A closer examination of a recent Cochrane network meta-analysis reveals several antidepressants with statistically and clinically significant positive outcomes for pain relief. The efficacy of antidepressants for chronic pain management has been historically studied for several decades, with TCAs such as amitriptyline showing efficacy in various pain conditions. SNRIs were developed […]
Read MoreAuthors: Joseph L. Staggenborg, MD, MBA, FASA et al ASA Monitor January 2024, Vol. 88, 18. This reservoir bag should be removed from its mount before using the machine when there is no central vacuum or waste anesthesia gas disposal. AGSS = anesthesia gas scavenging system. Photo by Dr. Loeb, used with permission. You arrive on […]
Read MoreAuthor: Richard Novak, MD THE ANESTHESIA CONSULTANT Anesthesiologists aren’t well known to most patients, but these specialty doctors have certain traits in common. Anesthesiologists are likely to have: A preference for being in an operating room rather than in a clinic. The practice of anesthesiology is the practice of perioperative medicine. Perioperative medicine has […]
Read MoreAuthor: Laura Dyrda Becker’s ASC Review California had the most new surgery centers in 2023, followed by Florida, Texas and Wisconsin. Surgery centers growth has accelerated as more procedures move to the outpatient setting and healthcare transitions to value-based care. Insurers are pushing surgeries into the outpatient setting and hospitals are expanding their ambulatory strategies. […]
Read MoreUpdated malaria vaccine recommendations from WHO The World Health Organization (WHO) has recommended a new vaccine, R21/Matrix-M, for the prevention of malaria in children. This recommendation aims to address the high burden of malaria in the WHO African Region, where nearly half a million children die from the disease annually. The vaccine is shown to […]
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