Author: Dr Clemens

Uncategorized Published - 19 January, 2024    By - Dr Clemens
Anatomical substrates of Rapid Eye Movement sleep rebound in a rodent model of post-sevoflurane sleep disruption

Authors: Navya Atluri, Ph.D. et al  Anesthesiology December 2023. Background Previous research suggests that sevoflurane anesthesia may prevent the brain from accessing REM sleep. If true, then patterns of neural activity observed in REM-on and REM-off neuronal populations during recovery from sevoflurane should resemble those seen after REM sleep deprivation. In this study we hypothesized […]

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Uncategorized Published - 19 January, 2024    By - Dr Clemens
New cancer diagnoses set to hit a new high in 2024: American Cancer Society

Author: Mariah Taylor Becker’s Hospital Review The expected increase in new cancer diagnoses this year is record-setting, even as overall cancer mortality is expected to continue its decline, the American Cancer Society said in its latest report. The report was based on the most recent data on population-based cancer occurrences and outcomes collected by central […]

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Uncategorized Published - 19 January, 2024    By - Dr Clemens
Overcoming Obstacles: The Legacy of Fidel Pagés, Founder of the Epidural, 100 Years After His Passing

I thought this was very interesting so I wanted to share. AUTHORS: Chinn, Gregory A. MD, PhD; Gray, Andrew T. MD, PhD; Larson, Merlin D. MD Anesthesia & Analgesia 138(2):p 475-479, February 2024.  Abstract Fidel Pagés, a Spanish surgeon, tragically died in 1923 at the age of 37, just 2 years after his publication “Anestesia […]

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Uncategorized Published - 19 January, 2024    By - Dr Clemens
Trends in Anesthesiology

Seizures in amygdala could lead to sudden unexpected death in epilepsy A research team supported by the National Institutes of Health (NIH) has identified a part of the brain that may be associated with breathing failure following a seizure in people with severe epilepsy that cannot be controlled with medication. This condition, known as sudden […]

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Uncategorized Published - 18 January, 2024    By - Dr Clemens
Clinical Outcomes, Blood Utilization, and Ethical Considerations for Pediatric Patients in a Bloodless Medicine and Surgery Program

AUTHORS: Lo, Brian D. MD et al  Anesthesia & Analgesia 138(2):p 465-474, February 2024. BACKGROUND: Pediatric patients requesting bloodless care represent a challenging clinical situation, as parents cannot legally refuse lifesaving or optimal interventions for their children. Here, we report clinical outcomes for the largest series of pediatric inpatients requesting bloodless care and also discuss the […]

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Uncategorized Published - 18 January, 2024    By - Dr Clemens
State-related Electroencephalography Microstate Complexity during Propofol- and Esketamine-Induced Unconsciousness

Authors: Zhenhu Liang, Ph.D. et al  Anesthesiology December 2023. Background Identifying the state-related “neural correlates of consciousness” for anesthetics-induced unconsciousness is challenging. Spatiotemporal complexity is a promising tool for investigating consciousness. We hypothesized that spatiotemporal complexity may serve as a state-related but not drug-related EEG indicator during an unconscious state induced by different anesthetic drugs […]

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Uncategorized Published - 18 January, 2024    By - Dr Clemens
Remimazolam for Intravenous Anesthesia

Radius Anesthesia In July 2020, remimazolam, a novel short-acting drug, was approved in the US for procedural sedation in adults (1). Like midazolam (a common anesthetic adjunct), remimazolam is a benzodiazepine and operates by modulating γ-aminobutyric acid (GABA) receptor activity to induce cell membrane hyperpolarization, thereby inhibiting neural activity via an increase in chloride ion […]

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Uncategorized Published - 18 January, 2024    By - Dr Clemens
What’s the best way to improve medication adherence in chronic pain management

Author: Morris D, Ferguson M. Ask the PharmD Pract Pain Manag. 2021;21(4). Treatment adherence strategies, including motivational interviewing and case vignettes. Medication adherence is an important part of assessment and disease management, yet it is still difficult for most patients. Nonadherence is linked to hospital admissions, worsehealth outcomes, increased morbidity/mortality, and higher healthcare-related costs. Around […]

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Uncategorized Published - 18 January, 2024    By - Dr Clemens
The workforce trends scaring physicians

Author: Patsy Newitt Becker’s ASC Review From consolidation to noncompetes, six physician leaders recently joined Becker’s to discuss the workforce trends that are concerning them. Editor’s note: These responses were edited lightly for clarity and length.  Clarissa Arthur, MD. Family Medicine Physician in Nashville, Tenn.: The workforce trend for physicians and providers that is most concerning is that […]

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Uncategorized Published - 18 January, 2024    By - Dr Clemens
Failure of Preclinical Studies to Accurately Predict the Effect of Regional Analgesia on Cancer Recurrence

AUTHORS: Juan P. Cata, M.D.; Daniel I. Sessler, M.D. Anesthesiology January 2024. The major goal of translational research is to evaluate the efficacy and effectiveness of treatments and interventions that have emerged from exhaustive preclinical evidence. In 2007, a major clinical trial was started to investigate the impact of paravertebral analgesia on breast cancer recurrence. The […]

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