Author: Dr Clemens

Uncategorized Published - 29 January, 2024    By - Dr Clemens
Preoperative Renin-Angiotensin System Antagonists Intake and Blood Pressure Responses During Ambulatory Surgical Procedures

AUTHORS: Gurunathan, Usha FANZCA et al  Anesthesia & Analgesia January 18, 2024. BACKGROUND: There is limited evidence to inform the association between the intake of angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin II receptor blockers (ARBs) and intraoperative blood pressure (BP) changes in an ambulatory surgery population. METHODS: Adult patients who underwent ambulatory surgery and were discharged on […]

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Uncategorized Published - 29 January, 2024    By - Dr Clemens
Tranexamic Acid Administration During Liver Transplantation Is Not Associated With Lower Blood Loss or With Reduced Utilization of Red Blood Cell Transfusion

AUTHORS: Dehne, Sarah MD et al  Anesthesia & Analgesia January 18, 2024. BACKGROUND: Current clinical guidelines recommend antifibrinolytic treatment for liver transplantation to reduce blood loss and transfusion utilization. However, the clinical relevance of fibrinolysis during liver transplantation is questionable, a benefit of tranexamic acid (TXA) in this context is not supported by sufficient evidence, […]

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Uncategorized Published - 29 January, 2024    By - Dr Clemens
Microglia Promote Inhibitory Synapse Phagocytosis in the Spinal Cord Dorsal Horn and Modulate Pain-Like Behaviors in a Murine Cancer-Induced Bone Pain Model

AUTHORS: Zhang, Zuoxia MD, PhD et al  Anesthesia & Analgesia January 19, 2024. BACKGROUND: The microglial activation has been implicated in cancer-induced bone pain. Recent studies have revealed that microglia mediate synaptic pruning in the central nervous system, where the cluster of differentiation 47-signal regulatory protein α (CD47-SIRPα) axis creates a “don’t eat me” signal […]

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Uncategorized Published - 29 January, 2024    By - Dr Clemens
Comparative Gene Signature of Nociceptors Innervating Mouse Molar Teeth, Cranial Meninges, and Cornea

AUTHORS: Sotelo-Hitschfeld, Pamela PhD et al  Anesthesia & Analgesia January 18, 2024. BACKGROUND: The trigeminal ganglion (TG) collects afferent sensory information from various tissues. Recent large-scale RNA sequencing of neurons of the TG and dorsal root ganglion has revealed a variety of functionally distinct neuronal subpopulations, but organ-specific information is lacking. METHODS: To link transcriptomic […]

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Uncategorized Published - 26 January, 2024    By - Dr Clemens
Trends shaping the business of health insurance in 2024

Author: Rebecca Pifer HealthcareDive Here’s what experts saw in their crystal balls for the coming year, including a spike in the uninsured rate and calmer waters in Medicare Advantage. The new year dawned on a health insurance industry beset by challenges. Only 7% of health plan executives view 2024 positively after being hammered by the coronavirus pandemic, […]

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Uncategorized Published - 26 January, 2024    By - Dr Clemens
Sevoflurane Postconditioning Protects From an Early Neurological Deficit After Subarachnoid Hemorrhage

AUTHORS: Morax, Laurent MD et al  Anesthesia & Analgesia January 19, 2024. BACKGROUND: Subarachnoid hemorrhage (SAH) is associated with neurocognitive impairment. Recent data suggest that sevoflurane attenuates edema formation after SAH in rats. However, so far, no information is available about the long-term repair phase, nor if sevoflurane impacts functionality by increasing vascularity. This study […]

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Uncategorized Published - 26 January, 2024    By - Dr Clemens
Factors Associated With Decision to Use and Dosing of Sugammadex in Children

AUTHORS: Brown, Sydney E.S. MD, PhD et al  Anesthesia & Analgesia January 19, 2024. BACKGROUND: Sugammadex was initially approved for reversal of neuromuscular blockade in adults in the United States in 2015. Limited data suggest sugammadex is widely used in pediatric anesthesia practice however the factors influencing use are not known. We explore patient, surgical, […]

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Uncategorized Published - 26 January, 2024    By - Dr Clemens
Gain Changers: New Generation of Weight Loss Medications

Authors: Dibash Kumar Das, PhD; Steven Shafer, MD, FASA ASA Monitor September 2023, Vol. 87, 1–4. Hosting the 95th Academy Awards, Jimmy Kimmel opened his monologue by saying, “Everybody looks so great! When I look around this room, I can’t help but wonder, ‘Is Ozempic right for me?’” Semaglutide (Ozempic, Wegovy, and Rybelsus) is blowing up social media […]

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Uncategorized Published - 26 January, 2024    By - Dr Clemens
10 best, worst states to start a business

Author: Riz Hatton Utah is the best state to start a business, while Rhode Island is the worst, according to personal finance site WalletHub. In a report released Jan. 16, WalletHub determined the best and worst places to start a business. The site compared the 50 states across three metrics: business environment, access to resources and business […]

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Uncategorized Published - 25 January, 2024    By - Dr Clemens
Associations Between Nonanemic Iron Deficiency and Postoperative Outcomes in Cardiac Surgery

AUTHORS: Peri, Varun MD et al  Anesthesia & Analgesia January 19, 2024. BACKGROUND: Preoperative screening for iron deficiency is a part of patient blood management protocols. This systematic review, meta-analysis, and meta-regression reviews the association between nonanemic iron deficiency and postoperative outcomes in patients undergoing cardiac surgery. We aimed to determine whether preoperative screening for […]

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