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Authors: Acharya, Mahip PhD et al The Clinical Journal of Pain 39(3):p 107-118, March 2023. Objective: To compare the safety profiles of low and high-dose tramadol, short-acting hydrocodone, and short-acting oxycodone therapies among chronic noncancer pain individuals. Materials and Methods: A retrospective cohort study of individuals with back/neck pain/osteoarthritis with an initial opioid prescription for tramadol, hydrocodone, or oxycodone was conducted using IQVIA PharMetrics […]
Read MoreAUTHORS: Belin, Olivier MD et al Anesthesia & Analgesia 136(3):p 540-550, March 2023. BACKGROUND: To counteract the vasoplegia induced by spinal anesthesia (SA) and maintain blood pressure (BP) during cesarean delivery, phenylephrine is currently recommended, but norepinephrine might offer superior preservation of cardiac output. We aimed to compare the hemodynamic effects of phenylephrine and norepinephrine administered […]
Read MoreAUTHORS: Brown, Sydney E. S. MD, PhD et al Anesthesia & Analgesia 136(6):p 1133-1142, June 2023. BACKGROUND: Neuromuscular/neurologic disease confers increased risk of perioperative mortality in children. Some patients require tracheostomy and/or feeding tubes to ameliorate upper airway obstruction or respiratory failure and reduce aspiration risk. Empiric differences between patients with and without these devices and […]
Read MoreAUTHORS: Guessous, K. MD et al Anesthesia & Analgesia April 03, 2023. BACKGROUND: Preoperative abnormal cognitive status is a risk factor for postoperative complications yet remains underdiagnosed. During propofol general anesthesia, intraoperative electroencephalography (EEG) variables, such as alpha band power (α-BP), correlate with cognitive status. This relationship under sevoflurane is unclear. We investigated whether […]
Read MoreAUTHORS: Jin, Sherry Y. FRCPC et al Anesthesia & Analgesia April 03, 2023. BACKGROUND: The incidence of failed spinal anesthesia varies widely in the obstetric literature. Although many risk factors have been suggested, their relative predictive value is unknown. The primary objective of this retrospective cohort study was to determine the incidence of failed spinal […]
Read MoreAUTHORS: Bose, Somnath MD, MPH, FASA et al Anesthesia & Analgesia 136(6):p 1115-1121, June 2023. BACKGROUND: Adverse effects of excessive sedation in critically ill mechanically ventilated patients are well described. Although guidelines strongly recommend minimizing sedative use, additional agents are added as infusions, often empirically. The tradeoffs associated with such decisions remain unclear. METHODS: To test […]
Read MoreAUTHORS: Xiao, Fei MD et al Anesthesia & Analgesia April 03, 2023. BACKGROUND: The dural puncture epidural (DPE) and the programmed intermittent epidural bolus (PIEB) techniques are recent innovations for labor analgesia. The optimal volume of PIEB during traditional epidural analgesia has been investigated previously but it is unknown whether these findings are applicable to […]
Read MoreAUTHORS: Siddiqui, Shahla MBBS, MS, FCCM et al Anesthesia & Analgesia 137(2):p 375-382, August 2023. BACKGROUND: Increased burnout and decreased professional fulfillment among intensive care physicians is partly due to intensive care unit (ICU) workload. Although the SARS-CoV-2 (COVID-19) pandemic increased ICU workload, it also may have increased feelings of personal fulfillment due to positive public […]
Read MoreAUTHORS: Li, Xiaoyun MD et al Anesthesia & Analgesia April 03, 2023. BACKGROUND: We aimed to determine the preventive and therapeutic efficacy of modified manual chest compression (MMCC), a novel noninvasive and device-independent method, in reducing oxygen desaturation events in patients undergoing upper gastrointestinal endoscopy under deep sedation. METHODS: A total of 584 outpatients who […]
Read MoreAUTHORS: Aceto, Paola et al European Journal of Anaesthesiology and Intensive Care 2(2):p e0019, April 2023. Abstract Steep and reverse Trendelenburg positions are often used in robotic-assisted surgery (RAS) to improve surgical access. The elderly are particularly vulnerable to the cardiovascular effect of the combination of pneumoperitoneum and these extreme positions. Falls in both cardiac output […]
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