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AUTHORS: Donovan, Anne L. MD et al BACKGROUND: Postoperative delirium is a common and serious problem for older adults. To better align local practices with delirium prevention consensus guidelines, we implemented a 5-component intervention followed by a quality improvement (QI) project at our institution. METHODS: This hybrid implementation-effectiveness study took place at 2 adult hospitals […]
Read MoreAuthors: Daniel Villalobos et al British Journals of Anaesthesia June 2023 Background Animal studies have shown that isoflurane and propofol have differential effects on Alzheimer’s disease (AD) pathology and memory, although it is unclear whether this occurs in humans. Methods This was a nested randomised controlled trial within a prospective cohort study; patients age ≥60 […]
Read MoreAuthors: Maria J. Susano, M.D. et al Anesthesiology December 2020, Vol. 133, 1184–1191. Background Frailty and cognitive impairment are associated with postoperative delirium, but are rarely assessed preoperatively. The study was designed to test the hypothesis that preoperative screening for frailty or cognitive impairment identifies patients at risk for postoperative delirium (primary outcome). Methods In this […]
Read MoreAuthors: Laura Li et al British Journal of Anaesthesia March 1, 2023 Background Postoperative cognitive dysfunction (POCD) is a concern after anaesthesia and surgery, but preoperative discussion of neurocognitive risks with older patients rarely occurs. Anecdotal experiences of POCD are common in the popular media and may inform patient perspectives. However, the degree of alignment […]
Read MoreAuthors: Yanmei Qi, PhD et al Anesthesiology August 2023. Background Intersectional genetics have yielded tremendous advances in our understanding of molecularly-identified subpopulations and circuits within the dorsal horn in neuropathic pain. We tested the hypothesis that spinal µ opioid receptor-expressing interneurons (Oprm1-INs) contribute to behavioral hypersensitivity and neuronal sensitization in the spared nerve injury model […]
Read MoreAuthors: S. Mark Poler, MD, FASA, DABA, DABPM(CI) et al ASA Monitor September 2023, Vol. 87, 19–20. How can large health systems support dispersed and underserved populations in remote, underfunded, and often understaffed rural facilities with obstetric and surgical needs? Rochester, New York, Danville, Pennsylvania, and Marshfield, Wisconsin, are not similar, but the populations supported […]
Read MoreAt Anesthesia Experts, we extend our heartfelt wishes for a joyful Labor Day to all our providers, readers, and supporters.
Read MoreAuthors: Peter L. Kovacs, M.D. et al Anesthesiology August 2023. The figure is from the preanesthetic airway assessment of a 56-yr-old man scheduled for laparoscopic hernia repair. His epiglottis was visible on tongue protrusion (unusual “Mallampati Zero” classification) and was adhered to the uvula as well. The patient related an uneventful past surgical history, although airway management […]
Read MoreAuthors: Lisa Q. Rong, MD et al Anesthesiology August 2023. Background Detailed understanding of the association between intraoperative left atrial (LA) and left ventricular (LV) diastolic function and postoperative atrial fibrillation (POAF) is lacking. In this post-hoc analysis of the PALACS (Posterior Left Pericardiotomy for the Prevention of Atrial Fibrillation after Cardiac Surgery) trial, we […]
Read MoreAuthors: Annalisa Boscolo, MD, PhD et al Anesthesiology August 2023. Background Diaphragm dysfunction and its effects on outcomes of ventilator weaning have been evaluated in mixed critical care populations using diaphragm thickening fraction (TFdi; the ratio of the difference between ultrasound diaphragm thickness at end-inspiration and end-expiration to diaphragm thickness at end-expiration) or neuro-ventilatory efficiency […]
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