Author: Dr Clemens

Uncategorized Published - 27 October, 2023    By - Dr Clemens
Bispectral Index Changes Following Boluses of Commonly Used Intravenous Medications During Volatile Anesthesia Identified From Retrospective Data

AUTHORS: Schnetz, Michael P. MD, PhD et al  Anesthesia & Analgesia August 15, 2023. BACKGROUND: Although patients are commonly monitored for depth of anesthesia, it is unclear to what extent administration of intravenous anesthetic medications may affect calculated bispectral (BIS) index values under general anesthesia. METHODS: In a retrospective analysis of electronic anesthesia records from […]

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Uncategorized Published - 27 October, 2023    By - Dr Clemens
The Antinociceptive Activity of (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide in Mice Is Reduced by (E)-3-(furan-2-yl)-N-methyl-N-(p-tolyl)acrylamide Through Opposing Modulatory Mechanisms at the α7 Nicotinic Acetylcholine Receptor

AUTHORS: Arias, Hugo R. PhD et al  Anesthesia & Analgesia 137(3):p 691-701, September 2023. BACKGROUND: The primary objective of this study was to characterize the pharmacological and behavioral activity of 2 novel compounds, DM497 [(E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide] and DM490 [(E)-3-(furan-2-yl)-N-methyl-N-(p-tolyl)acrylamide], structural derivatives of PAM-2, a positive allosteric modulator of the α7 nicotinic acetylcholine receptor (nAChR). METHODS: A mouse […]

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Uncategorized Published - 27 October, 2023    By - Dr Clemens
Influence of Fibrinogen Concentrate on Neonatal Clot Structure When Administered Ex Vivo After Cardiopulmonary Bypass

AUTHORS: Moiseiwitsch, Nina BS et al  Anesthesia & Analgesia 137(3):p 682-690, September 2023. BACKGROUND: Bleeding is a serious complication of cardiopulmonary bypass (CPB) in neonates. Blood product transfusions are often needed to adequately restore hemostasis, but are associated with significant risks. Thus, neonates would benefit from other effective, and safe, hemostatic therapies. The use of fibrinogen […]

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Uncategorized Published - 27 October, 2023    By - Dr Clemens
Lack of Useful Predictors of Dignity-Related Distress Among the Critically Ill as Assessed With the Patient Dignity Inventory

AUTHORS: Hadler, Rachel A. MD et al  Anesthesia & Analgesia 137(3):p 676-681, September 2023. BACKGROUND: Many intensive care unit patients are awake (ie, alert and engaging in conversation), actively experiencing many facets of their critical care. The Patient Dignity Inventory can be used to elicit sources of distress in these patients. We examined the administrative question […]

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Uncategorized Published - 27 October, 2023    By - Dr Clemens
Understanding the changes in migraine treatment

Author: ELAINE C. TIMM, MD KevinMD.com As a primary care provider (PCP) specializing in headaches and migraine, I cannot stress enough the important role of PCPs in diagnosing and treating migraine disease. Almost 40 million Americans and over a billion people worldwide live with migraine and the significant burden that comes with the disease. Migraine […]

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Uncategorized Published - 26 October, 2023    By - Dr Clemens
A Pilot Investigation Evaluating Relative Changes in Fronto-Occipital Alpha and Beta Spectral Power as Measurement of Anesthesia Hypnotic Depth

AUTHORS: Fehrlin, Eloy S. MD et al Anesthesia & Analgesia 137(3):p 656-664, September 2023. BACKGROUND: Other than clinical observation of a patient’s vegetative response to nociception, monitoring the hypnotic component of general anesthesia (GA) and unconsciousness relies on electroencephalography (EEG)-based indices. These indices exclusively based on frontal EEG activity neglect an important observation. One of the […]

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Uncategorized Published - 26 October, 2023    By - Dr Clemens
Loss of Independent Living in Patients Undergoing Transcatheter or Surgical Aortic Valve Replacement

AUTHORS: Blank, Michael Cand.Med et al  Anesthesia & Analgesia 137(3):p 618-628, September 2023. BACKGROUND: The recommendation for transcatheter aortic valve replacement (TAVR) or surgical aortic valve replacement (SAVR) in patients 65 to 80 years of age is equivocal, leaving patients with a difficult decision. We evaluated whether TAVR compared to SAVR is associated with reduced odds […]

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Uncategorized Published - 26 October, 2023    By - Dr Clemens
Sociodemographic Disparities in Postoperative Nausea and Vomiting

AUTHORS: Lee, Donaldson C. MD et al  Anesthesia & Analgesia 137(3):p 665-675, September 2023. BACKGROUND: Postoperative nausea and vomiting (PONV) prophylaxis is consistently considered a key indicator of anesthesia care quality. PONV may disproportionately impact disadvantaged patients. The primary objectives of this study were to examine the associations between sociodemographic factors and the incidence of PONV […]

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Uncategorized Published - 26 October, 2023    By - Dr Clemens
A Prospective, Randomized Comparison of the Classical Altemir’s Method With the Newer Seldinger’s Technique of Submental Intubation

AUTHORS: S P S, Aswin Ram MD et al  Anesthesia & Analgesia 137(3):p 638-647, September 2023. BACKGROUND: Submental intubation performed using the classical Altemir’s technique is a well-accepted, safe technique for providing optimal operating field to the maxillofacial surgeon, in cases where either nasotracheal or orotracheal intubation is impossible. We propose a new, percutaneous Seldinger’s technique […]

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Uncategorized Published - 26 October, 2023    By - Dr Clemens
Trial set for anesthesiologist accused of tampering with IV bags at ASC

Author: Patsy Newitt Becker’s ASC Review The trial for anesthesiologist Raynaldo Ortiz Jr., MD, who allegedly injected heart-stopping drugs into IV bags at Baylor Scott & White Surgicare North Dallas, has been set for Feb. 5, D Magazine reported Oct. 20. A judge set a date following motions for continuance from Dr. Ortiz’s attorney over the last […]

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