Author: Dr Clemens

Uncategorized Published - 21 November, 2023    By - Dr Clemens
Dexmedetomidine Pretreatment Protects Against Myocardial Ischemia/Reperfusion Injury by Activating STAT3 Signaling

AUTHORS: Chen, Zhao-Rong MM et al  Anesthesia & Analgesia 137(2):p 426-439, August 2023. BACKGROUND: Myocardial infarction is a common perioperative complication, and blood flow restoration causes ischemia/reperfusion injury (IRI). Dexmedetomidine (DEX) pretreatment can protect against cardiac IRI, but the mechanism is still insufficiently understood. METHODS: In vivo, myocardial ischemia/reperfusion (30 minutes/120 minutes) was induced via ligation […]

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Uncategorized Published - 21 November, 2023    By - Dr Clemens
Project SPRUCE: Saving Our Planet by Reducing Carbon Emissions, a Pediatric Anesthesia Sustainability Quality Improvement Initiative

AUTHORS: Hansen, Elizabeth E. MD, PhD et al  Anesthesia & Analgesia 137(1):p 98-107, July 2023. BACKGROUND: Children are particularly vulnerable to adverse health outcomes related to climate change. Inhalational anesthetics are potent greenhouse gasses (GHGs) and contribute significantly to health care–generated emissions. Desflurane and nitrous oxide have very high global warming potentials. Eliminating their use, as […]

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Uncategorized Published - 21 November, 2023    By - Dr Clemens
Management of Muscle Relaxation With Rocuronium and Reversal With Neostigmine or Sugammadex Guided by Quantitative Neuromuscular Monitoring

AUTHORS: Thilen, Stephan R. MD, MS et al  Anesthesia & Analgesia May 12, 2023. BACKGROUND: The optimal pharmacological reversal strategy for neuromuscular blockade remains undefined even in the setting of strong recommendations for quantitative neuromuscular monitoring by several national and international anesthesiology societies. We evaluated a protocol for managing rocuronium blockade and reversal, using quantitative […]

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Uncategorized Published - 20 November, 2023    By - Dr Clemens
Tracheal Narrowing and Its Impact on Anesthesia Care in Patients With Morquio A (Mucopolysaccharidosis Type IVA)

AUTHORS: Theroux, Mary C. MD et al  Anesthesia & Analgesia 137(5):p 1075-1083, November 2023. BACKGROUND:  Recently, tracheal narrowing has been recognized as a significant comorbid condition in patients with Morquio A, also known as mucopolysaccharidosis IVA. We studied a large cohort of patients with Morquio A to describe the extent of their tracheal narrowing and its […]

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Uncategorized Published - 20 November, 2023    By - Dr Clemens
The Timing of Initiating Hydrocortisone and Long-term Mortality in Septic Shock

AUTHORS: Zhang, Luming MD, PhD et al  Anesthesia & Analgesia 137(4):p 850-858, October 2023. BACKGROUND: Previous studies on the association between the timing of corticosteroid administration and mortality in septic shock focused only on short-term mortality and produced conflicting results. We performed a retrospective review of a large administrative database of intensive care unit (ICU) patients […]

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Uncategorized Published - 20 November, 2023    By - Dr Clemens
Ondansetron for the Prevention of Pruritus in Women Undergoing Cesarean Delivery With Intrathecal Opioid

AUTHORS: Cadd, Matthew MRCP et al  Anesthesia & Analgesia May 11, 2023. BACKGROUND: Pruritus is a frequently reported and unpleasant side effect following intrathecal opioid use with frequency further increased among parturients. We have performed a systematic review to assess the overall efficacy of ondansetron for the prevention of pruritus in patients receiving intrathecal opioid […]

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Uncategorized Published - 20 November, 2023    By - Dr Clemens
Chronic Pain, Analgesics, and Cognitive Status

AUTHORS: Guo, Xingzhi MD, PhD et al Anesthesia & Analgesia 137(4):p 896-905, October 2023. BACKGROUND: Observational studies have suggested an intricate relationship among chronic pain (CP), use of analgesics, and cognitive status, but it remains unclear whether these associations are of a causal nature. METHODS: To investigate the causal relationship among them, summary statistics of 9 […]

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Uncategorized Published - 20 November, 2023    By - Dr Clemens
Public Knowledge and Awareness of Anesthesiology and Anesthesiologists in China

AUTHORS: Ma, Yulong MD, PhD et al  Anesthesia & Analgesia May 04, 2023. BACKGROUND: In the past 20 years, anesthesiology has become one of the most advanced specialties and has undergone rapid development. However, public awareness regarding anesthesiology and anesthesiologists is limited, especially in developing countries. It is important for anesthesiologists to make the public […]

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Uncategorized Published - 17 November, 2023    By - Dr Clemens
Implementation of Nephroprotective Measures to Prevent Acute Kidney Injury in Septic Patients

AUTHORS: Sadjadi, Mahan MD et a  Anesthesia & Analgesia May 09, 2023. BACKGROUND: Sepsis remains the leading cause of mortality in critically ill patients, and mortality is increased when acute kidney injury (AKI) occurs. The Kidney Disease: Improving Global Outcomes (KDIGO) guideline recommends the implementation of supportive measures in patients at high risk for AKI. […]

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Uncategorized Published - 17 November, 2023    By - Dr Clemens
Health System Supports to Rural Anesthesiology Consultants

Authors: S. Mark Poler, MD, FASA, DABA, DABPM(CI) et al  ASA Monitor September 2023, Vol. 87, 19–20. How can large health systems support dispersed and underserved populations in remote, underfunded, and often understaffed rural facilities with obstetric and surgical needs? Rochester, New York, Danville, Pennsylvania, and Marshfield, Wisconsin, are not similar, but the populations supported by […]

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