Author: Dr Clemens

Uncategorized Published - 31 May, 2024    By - Dr Clemens
Gastric pressure monitoring unveils abnormal patient-ventilator interaction related to active expiration: a retrospective observational study

Authors: Evangelia Akoumianaki, M.D., Ph.D. et al  Anesthesiology May 2024. Background Patient-ventilator dyssynchrony is frequently observed during assisted mechanical ventilation (MV). However, the effects of expiratory muscle contraction on patient-ventilator interaction are underexplored. We hypothesized that active expiration would affect patient-ventilator interaction and we tested our hypothesis in a mixed cohort of invasively ventilated patients […]

Read More
Uncategorized Published - 31 May, 2024    By - Dr Clemens
Perioperative Acute Renal Injury

Author: Robert N. Sladen, M.B.Ch.B., M.R.C.P.(U.K.), F.R.C.P.C., F.C.C.M. Anesthesiology May 2024. Background Acute renal dysfunction and subsequent acute renal failure after cardiac surgery are associated with high mortality and morbidity. Early therapeutic or preventive intervention is hampered by the lack of an early biomarker for acute renal injury. Recent studies showed that urinary neutrophil gelatinase–associated […]

Read More
Uncategorized Published - 31 May, 2024    By - Dr Clemens
Electrical Impedance Tomography for Assessing the Impact of Inhaled Nitric Oxide on Pulmonary Artery Pressure

Authors: Gamonmas Ekkapat, M.D. et al  Anesthesiology May 2024. A 43-yr-old woman experienced acute respiratory failure with right ventricular dysfunction following a complex left pneumonectomy (fig. 1A) with cardiopulmonary bypass. She was intubated and mechanically ventilated. Fig. 1. (A) Chest x-ray showing patchy opacities at the right middle and lower lung zones along with loculated […]

Read More
Uncategorized Published - 30 May, 2024    By - Dr Clemens
A Practical Dosing Algorithm for Deep Neuromuscular Blockade During Total Intravenous Anesthesia

Authors: Kim I. Albers-Warlé, MD et al Anesthesiology May 2024. Background The number of trials investigating the effects of deep neuromuscular blockade (NMB) on surgical conditions and patient outcomes is steadily increasing. Consensus on which surgical procedures benefit from deep NMB (a post tetanic count of 1-2) and how to implement it has not been […]

Read More
Uncategorized Published - 30 May, 2024    By - Dr Clemens
Accuracy and Precision of Three Acceleromyographs, Three Electromyographs and a Mechanomyograph Measuring the Train-of-Four Ratio in the Absence of Neuromuscular Blocking Drugs

Authors: Zain Wedemeyer, BS et al  Anesthesiology May 2024. Background The accuracy and precision of currently available, widely used acceleromyograph and electromyograph neuromuscular blockade monitors have not been well studied. In addition, the normalization of the train-of-four ratio from acceleromyography (train-of-four ratio [T4/T1] divided by the baseline train-of-four ratio) has not been validated in comparison […]

Read More
Uncategorized Published - 30 May, 2024    By - Dr Clemens
Pain during Cesarean Delivery: We Can and Must Do Better

Authors: Mark I. Zakowski, M.D. et al  Anesthesiology June 2024, Vol. 140, 1236–1237. To the Editor: The American Society of Anesthesiologists (ASA; Schaumburg, Illinois) House of Delegates recently approved the “Statement on Pain during Cesarean Delivery” from the Committee on Obstetric Anesthesia advising all practitioners on the pervasive problem of failure to achieve pain-free cesarean delivery. […]

Read More
Uncategorized Published - 30 May, 2024    By - Dr Clemens
Preoperative N-Terminal Pro–B-Type Natriuretic Peptide and High-Sensitivity Cardiac Troponin T and Outcomes After Major Noncardiac Surgery

Authors: Bingcheng Zhao, MD et al  Anesthesiology May 2024. Background Patients undergoing noncardiac surgery have varying risk of cardiovascular complications. This study evaluated preoperative N-terminal pro–B-type natriuretic peptide and high-sensitivity cardiac troponin T to enhance cardiovascular events prediction for major noncardiac surgery. Methods This prospective cohort study included adult patients with cardiovascular disease or risk factors […]

Read More
Uncategorized Published - 30 May, 2024    By - Dr Clemens
Improving Dantrolene Mobilization in Regions with Limited Availability

Authors: Hong Yu, M.D. et al  Anesthesiology June 2024, Vol. 140, 1201–1202. Figure 1 depicts the user interface of the National Remote Emergency System for Malignant Hyperthermia for dantrolene mobilization in China. In National Remote Emergency System for Malignant Hyperthermia, dantrolene can be mobilized in three steps: (1) calculating the minimum dantrolene vials needed; (2) identifying […]

Read More
Uncategorized Published - 29 May, 2024    By - Dr Clemens
Exposure to Operative Anesthesia in Childhood and Subsequent Neurobehavioral Diagnoses

Authors: Jeffrey H. Silber, MD, PhD et al Anesthesiology May 2024. Background Observational studies of anesthetic neurotoxicity may be biased because children requiring anesthesia commonly have medical conditions associated with neurobehavioral problems. This study takes advantage of a natural experiment associated with appendicitis, in order to determine if anesthesia and surgery in childhood were specifically […]

Read More
Uncategorized Published - 29 May, 2024    By - Dr Clemens
Novel Resuscitation Strategies in Severe Trauma: Reply

Authors: David J. Douin, M.D.; Ana Fernandez-Bustamante, M.D., Ph.D., FASA. Anesthesiology June 2024, Vol. 140, 1238–1239. In Reply: We are grateful to Drs. Kowalczyk and Farber for their thorough review and insightful response to our recent clinical focused review of the administration of fibrinogen to mitigate endothelial dysfunction after acute traumatic injury. We appreciate their constructive critique regarding […]

Read More