Author: Dr Clemens

Uncategorized Published - 19 June, 2024    By - Dr Clemens
Anesthesia blunts carbon dioxide effects on glymphatic cerebrospinal fluid dynamics in mechanically ventilated rats

Authors: L Niklas Daniel Åke Persson, M.Sc. et al  Anesthesiology May 2024. Background Impaired glymphatic clearance of cerebral metabolic products and fluids contribute to traumatic and ischemic brain oedema and neurodegeneration in preclinical models. Glymphatic perivascular cerebrospinal fluid (CSF) flow varies between anesthetics possibly due to changes in vasomotor tone and thereby in the dynamics […]

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Uncategorized Published - 19 June, 2024    By - Dr Clemens
The Color of Climate Change: Can Choice of Anesthetic Be Institutionally Racist?

Authors: Baker, Maxwell B. MSc et al  Anesthesia & Analgesia 138(6):p 1154-1158, June 2024. | In the United States, the health care sector is responsible for 10% of the nation’s carbon emissions.1 Anesthesia-related care is responsible for 5% of total health care carbon emissions.2 Within hospitals themselves, as much as 33% of waste is produced by perioperative services.3 Medical […]

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Uncategorized Published - 19 June, 2024    By - Dr Clemens
Wiretap Laws: Relevance to Clinical Practice and Patient Safety

Author: Karolina Brook, MD, FASA, CPPS Anesthesia Patient Safety Foundation June 2024 Volume 39, No. 2 SUMMARY:Wiretap laws govern the legality of audio recordings and vary state to state. Here, we summarize the various states’ wiretap laws, the remedies or punishments that can be exacted for violation of a wiretap law, and the applicability of […]

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Uncategorized Published - 18 June, 2024    By - Dr Clemens
Intraoperative Hypotension: A Public Safety Announcement for Anesthesia Professionals

Authors: Amy Yerdon, DNP, MNA, CRNA, CNE, CHSE et al  Anesthesia Safety Patient Foundation June 2024 Volume 39, No. 2 SUMMARY Mounting evidence supports an association between intraoperative hypotension (IOH) and negative postoperative outcomes, most significantly acute kidney injury (AKI), myocardial injury after non-cardiac surgery, and mortality. Recent studies also show associations between IOH and […]

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Uncategorized Published - 18 June, 2024    By - Dr Clemens
Unraveling a Recurrent Wrong Drug-Wrong Route Error—Tranexamic Acid in Place of Bupivacaine

Authors: Paul A. Lefebvre, JD et al  Anesthesia Safety Patient Foundation June 2024 Volume 39, No. 2  INTRODUCTION . Notwithstanding technological advances and the ongoing efforts of patient safety advocates, medication administration errors routinely occur in health care facilities across the country.1-2 Each day, anesthesia professionals overcome challenges that commonly contribute to medication errors, such as […]

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Uncategorized Published - 18 June, 2024    By - Dr Clemens
Opioid-Induced Respiratory Depression—Pediatric Considerations

Authors: Tricia Vecchione, MD, MPH; Constance L. Monitto, MD Anesthesia Patient Safety Foundation June 2024 Volume 39, No. 2  SUMMARY:Opioid-induced respiratory depression can be a life-threatening, albeit preventable, complication in children. It is imperative to identify those at risk for opioid-induced respiratory depression and formulate safer practices, including the use of opioid-sparing adjuncts, frequent sedation […]

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Uncategorized Published - 18 June, 2024    By - Dr Clemens
Association of Neighborhood Opportunity, Race and Ethnicity with Pediatric Day-of-Surgery Cancellations

Authors: Brittany L. Willer, MD et al  Anesthesiology May 2024. Background Day-of-surgery cancellations impede healthcare access and contribute to inequities in pediatric healthcare. Socially disadvantaged families have many risk factors for surgical cancellation, including low health literacy, transportation barriers, and childcare constraints. These social determinants of health are captured by the Childhood Opportunity Index (COI) […]

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Uncategorized Published - 18 June, 2024    By - Dr Clemens
Effects of hemorrhagic shock and rhabdomyolysis on renal microcirculation, oxygenation and function in a female swine model

Authors: Benjamin Bergis, MD, Msc et al  Anesthesiology May 2024. Background Hemorrhagic shock (HS) and rhabdomyolysis (RM) are two important risk factors of acute kidney injury (AKI) after severe trauma, however the effects of the combination of RM and HS on kidney function are unknown. The purpose of this study was to determine the impact […]

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Uncategorized Published - 17 June, 2024    By - Dr Clemens
Combined Dexamethasone and Dexmedetomidine as Adjuncts to Popliteal and Saphenous Nerve Blocks in Patients Undergoing Surgery of the Foot or Ankle

Authors: Mathias Maagaard, M.D. et al  Anesthesiology June 2024, Vol. 140, 1165–1175. Background Both dexamethasone and dexmedetomidine increase the duration of analgesia of peripheral nerve blocks. The authors hypothesized that combined intravenous dexamethasone and intravenous dexmedetomidine would result in a greater duration of analgesia when compared with intravenous dexamethasone alone and placebo. Methods The authors randomly […]

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Uncategorized Published - 17 June, 2024    By - Dr Clemens
Long-term Survival after Volatile or Propofol General Anesthesia for Bladder Cancer Surgery

Authors: Mats Enlund, M.D., Ph.D. et al  Anesthesiology June 2024, Vol. 140, 1126–1133. Background Prospective interventional trials and retrospective observational analyses provide conflicting evidence regarding the relationship between propofol versus inhaled volatile general anesthesia and long-term survival after cancer surgery. Specifically, bladder cancer surgery lacks prospective clinical trial evidence. Methods Data on bladder cancer surgery performed under general […]

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