AUTHORS: Kintrup, Sebastian MD et al Anesthesia & Analgesia 140(5):p 1073-1082, May 2025. BACKGROUND: Procalcitonin is an indicator of systemic inflammation associated with major surgery or sepsis. Procalcitonin exists in a full-length and truncated variant as a result of dipeptidylpeptidase-4 (DPP4)-cleavage. We recently identified differential biological activity of both variants. Here, we present an immunoassay-based method […]
Read MoreAUTHORS: Yang, Seonkyeong PhD et al Anesthesia & Analgesia 140(5):p 1205-1215, May 2025. BACKGROUND: Racial disparities exist in access to health care and management of multiple health conditions including chronic pain; however, racial disparities in pre- and postoperative pain management in lower extremity amputation are not well-studied. Our objective was to examine the association between different […]
Read MoreAUTHORS: Liou, Jing-Yang MD, PhD et al Anesthesia & Analgesia 140(5):p 1168-1177, May 2025. BACKGROUND: The aim of this study was to explore a new method for determining optimal dosing regimens for combinations of propofol, midazolam, and an opioid to achieve rapid on- and off-set of deep sedation. METHODS: We simulated 16 published dosing regimens using […]
Read MoreAUTHORS: Coeckelenbergh, Sean MD et al Anesthesia & Analgesia 140(5):p 1149-1158, May 2025. BACKGROUND: Implementation of goal-directed fluid therapy (GDFT) protocols remains low. Protocol compliance among anesthesiologists tends to be suboptimal owing to the high workload and the attention required for implementation. The assisted fluid management (AFM) system is a novel decision support tool designed to […]
Read MoreAuthors: Bruzzone, Maria J. MD, MSCR et al Anesthesia & Analgesia 140(5):p 1127-1139, May 2025. | Abstract Postoperative delirium (POD) is frequent in older adults and is associated with adverse cognitive and functional outcomes. In the last several decades, there has been an increased interest in exploring tools that easily allow the early recognition of patients at […]
Read MoreAuthor: Patsy Newitt Becker’s ASC Review CMS recently proposed a series of payment updates across multiple care settings for fiscal year 2026. ASCs are impacted directly, but the changes could affect care delivery dynamics. Here are 10 things to know: 1. CMS proposed a 2.4% payment increase for inpatient hospitals, translating to a $4 billion funding surge. […]
Read MoreAuthors: Rolfzen, Megan L. MD et al Anesthesia & Analgesia 140(5):p 1012-1014, May 2025. | Significant attention, time, and research have been devoted to the reduction of opioid consumption, both in the context of chronic pain treatment and for perioperative use. The 2023 Lancet Commission was dedicated to understanding the causes of the opioid crisis and headlining […]
Read MoreWe’re excited to announce the formation of a new anesthesia group in Riverdale, GA, located just 10 minutes from the Atlanta Airport. We’re seeking dedicated CRNAs to join our collaborative care team, which will include 4 full-time CRNAs and 2 anesthesiologists managing 4 operating rooms. This is a 25% independent practice and doing own blocks! […]
Read MoreIf you’re an anesthesiologist searching for a balanced lifestyle and rewarding work, you’ll want to check out this opportunity. Our all-anesthesiologist group is seeking a dedicated team member to join our collaborative practice. Position Highlights: Zero Call for 3 Weeks: Enjoy three weeks of no call duty, followed by one week of call. Even during […]
Read MoreAUTHORS: Koh, Ye Rin MD et al Anesthesia & Analgesia 140(5):p 1178-1187, May 2025. BACKGROUND: Both intraoperative hypotension and excessive fluid administration can lead to detrimental perioperative complications. However, how much fluid is considered excessive and how is intraoperative hypotension related to major postoperative complications? METHODS: We conducted a single-center retrospective cohort study in 6243 patients […]
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