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Published in The Journal of the American Society of Anesthesiologists on 1 2015. Authors: Nicholas P. Franks, F.R.C.A., F.Med.Sci., F.R.S. Background: Most anesthetics, particularly intravenous agents such as propofol and etomidate, enhance the actions of the neurotransmitter γ-aminobutyric acid (GABA) at the GABA type A receptor. However, there is no agreement as where anesthetics bind […]
Read MorePublished in The Journal of the American Society of Anesthesiologists on 1 2015. Authors: Lianyan Huang, Ph.D.; Guang Yang, Ph.D. Background: Recent studies in rodents suggest that repeated and prolonged anesthetic exposure at early stages of development leads to cognitive and behavioral impairments later in life. However, the underlying mechanism remains unknown. In this study, […]
Read MorePublished in The Journal of the American Society of Anesthesiologists in 1 2015. Authors: Jochen D. Muehlschlegel, M.D. et al Danos C. Christodoulou, Ph.D. Background: The exact mechanisms that underlie the pathological processes of myocardial ischemia in humans are unclear. Cardiopulmonary bypass with cardioplegic arrest allows the authors to examine the whole transcriptional profile of […]
Read MoreAuthors: Ikuomi Mikuni, M.D., Ph.D. et al Published in The Journal of the American Society of Anesthesiologists on 1 2015. Background: The impact of volatile anesthetics on patients with inherited long QT syndrome (LQTS) is not well understood. This is further complicated by the different genotypes underlying LQTS. No studies have reported on the direct […]
Read MoreAuthors: Webster L, Smith M, Mackin S, Iverson M Published in Pain Medicine (Oct 2014) OBJECTIVE To investigate effects of extended-release (ER) hydromorphone dosing time (morning, QAM; evening, QPM) on sleep physiology in patients with chronic low back pain. DESIGN Randomized, double-blind, placebo-controlled, crossover trial. SETTING Clinical research site. PATIENTS Fifteen patients with moderate-to-severe chronic low […]
Read MorePublished in Der Anaesthesist (Oct 2014) Authors: Zech N, Seemann M, Hansen E; Anesthetists have an impact on patients and healing processes not only through drugs, interventions and therapy but also significantly by their words and personality. A substantial part of observed side effects is caused by nocebo effects and negative suggestion, i.e. by the doctor […]
Read MorePublished in International Journal of Pediatric Otorhinolaryngology 78 (10), 1735-41 (Oct 2014) Authors: Tong Y, Ding X, Wang X, Ren H, Chen Z, Li Q OBJECTIVES Peri-operative ketamine peritonsillar infiltration in children can reduce the incidence of postoperative nausea and vomiting (PONV), but its postoperative analgesic time is short. A previous meta-analysis in 2011 was […]
Read MoreI thought this was interesting so I wanted to share it with our followers who treat chronic pain. Emergency departments generate fewer prescriptions for opioid analgesics and are less likely to prescribe high doses for relief of noncancer pain than office-based practices, a new study has found.”While we are sensitive to the need to develop […]
Read MoreEvents during surgery, especially intraoperative awareness, can lead to post-traumatic stress disorder (PTSD), investigators report. Healthcare-associated PTSD can also be triggered by a stay in the intensive care unit (ICU), the use of mechanical ventilation, and cardiac arrest, said Elizabeth Whitlock MD, from the University of California, San Francisco. However, “other than awareness, risk factors […]
Read MoreThere are at least 30 ways to grow patient satisfaction at your healthcare facility, but 10 key service standards should do the trick. Increasing patient satisfaction is challenging, but necessary to the success of a medical practice in an increasingly competitive healthcare marketplace. Identify low patient satisfaction scores and work as a team to design, […]
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