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Neosaxitoxin, a novel site 1 sodium channel blocker, significantly prolonged sensory blockade when combined with bupivacaine, with or without epinephrine, in the first-in-human trial of this compound. The study, presented here at Anesthesiology 2014, was distinguished as the Best Clinical Abstract. “Neosaxitoxin prolonged local anesthesia, when given either alone or with bupivacaine or epinephrine, while […]
Read MorePublished in Anaesth Crit Care and Pain. 2014;14(4):147-152. Introduction The type of surgery performed on the spine encompasses operations for trauma, deformity, and myelopathy. The complexity of procedures is continuing to increase and older patients with significant co-morbidities are being offered ever more major procedures for which they would have previously not been considered. Increasing […]
Read MorePublished in J Bone Joint Surg Am 2015 Feb 4; 97:e18 Authors: Sharrock NE. In an observational study, most outcomes favored regional anesthesia. For patients undergoing total hip arthroplasty, some evidence suggests that perioperative outcomes are more favorable with regional anesthesia than with general anesthesia. To shed additional light on this issue, U.S. researchers accessed […]
Read MoreThe number of patients reporting moderate to severe pain two weeks after surgery has decreased by 24% in the last decade, a new study found. Researchers surveyed 441 patients before they were discharged from the hospital, and then at one, two and three weeks after surgery. Patients were asked to rate their pain intensity and […]
Read MorePublished in Reg Anesth Pain Med. 2014 Nov-Dec;39(6):472-7. Authors: Terkawi AS et al BACKGROUND: One of the modalities of treatment for breast cancer surgery pain is opioids, and opioids are associated with adverse effects such as itching and postoperative nausea and vomiting (PONV). Intravenous (IV) lidocaine has been shown to reduce opioid consumption and to […]
Read MoreAcute lung damage related to blood transfusions continues to affect about one in every 100 surgery patients, despite efforts to reduce the incidence of the life-threatening condition. Anesthesiologists at Mayo Clinic found that the rate of transfusion-related acute lung injury (TRALI) decreased between 2004 and 2011 against a backdrop of various novel mitigation strategies. Another […]
Read MoreA consensus statement on the possible link of anesthetic technique and anesthetic agents to risk for cancer and cancer recurrence underscores lack of definitive evidence and the need for further research. The statement was recently published in the British Journal of Anaesthesia. The experts concluded that, although there are conflicting views on whether anesthetic technique […]
Read MoreAnita Gupta, DO, PharmD, described tubing misconnections as “a reality” of the practice of anesthesiology and the delivery of treatment in hospitals, long-term care centers and hospital facilities. However, Dr. Gupta, vice-chair of the Division of Pain Medicine and Regional Anesthesiology and associate professor, Department of Anesthesiology and Perioperative Medicine, Drexel University College of Medicine, […]
Read MoreReg Anesth Pain Med. 2014 Nov-Dec;39(6):506-12 Authors: Chen H et al BACKGROUND AND OBJECTIVES: We hypothesized that continuous right thoracic paravertebral block, following bolus initiation, decreases opioid consumption after right-lobe hepatectomy in patients receiving patient-controlled intravenous analgesia with sufentanil. METHODS: Patients undergoing right-lobe hepatectomy with a right thoracic paravertebral catheter placed at T7 30 minutes […]
Read MoreSignificant airway changes occur during the administration of general anaesthesia, including a decrease in patients’ intraoral space and an increase in their neck thickness, according to results of a prospective cohort study presented at the 2014 Annual Meeting of the American Society of Anesthesiologists (ASA). After extubation following general anaesthesia, the risk of difficult laryngoscopy […]
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