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Published in Ann Emerg Med 2014 Oct 22 Authors: Weingart SD et al. In a new technique called “delayed sequence intubation,” ketamine facilitated preoxygenation in patients with altered mental status. Patients with altered mental status may not be able to undergo preoxygenation, which is required for optimal rapid sequence intubation. In a prospective observational study […]
Read MorePublished in Ann Emerg Med 2014 Oct 15 Authors: Miner JR et al. In a randomized trial, three drug regimens for procedural sedation were equivalent, but the analysis was flawed. For procedural sedation, the advantage of propofol is its short duration; its disadvantage is dose-related respiratory suppression. The advantage of ketamine is absence of respiratory […]
Read MoreRoughly two thirds of children with severe head injuries who undergo computed tomography scans have traumatic brain injuries, according to an analysis of emergency department visits for pediatric head trauma published in the New England Journal of Medicine. Researchers studied some 43,000 children who presented with blunt head trauma from 2004 through 2006. Among the […]
Read MorePublished The Lancet Psychiatry. Both pain and depression are independent and interactive risk factors for delirium, suggesting a cumulative effect. “Understanding the impact of preoperative pain and depression on risk of delirium in older surgical patients is important,” said lead author Cyrus Kosar, MD, Harvard Medical School, and Hebrew Senior Life Institute for Aging Research […]
Read MoreCommonly prescribed, older drugs for arthritis and pain may increase the risk of death from stroke, according to a study published in the journal Neurology. The drugs examined in the study, COX-2 inhibitors, include older drugs diclofenac, etodolac, nabumeton and meloxicam, as well as newer drugs, including celecoxib and rofecoxib. The study also looked at […]
Read MorePublished in Crit Care. 2014;18 Authors: Vance Beck et al Introduction: Despite recent advances in the management of septic shock, mortality remains unacceptably high. Earlier initiation of key therapies including appropriate antimicrobials and fluid resuscitation appears to reduce the mortality in this condition. This study examined whether early initiation of vasopressor therapy is associated with […]
Read MorePublished in Clinical Interventions in Aging 10 1-11 (2015) Authors: Guerriero F et al PURPOSE Chronic pain is highly prevalent in older adults. Increasing evidence indicates strong opioids as a valid option for chronic pain management in geriatrics. The aim of this study was to evaluate efficacy and safety of low-dose oral prolonged-release oxycodone-naloxone (OXN-PR) […]
Read MorePublished in BMC Anesthesiol. 2014;14(44) Authors: James M Blum et al Background: The impact of anesthetic equipment on clinical practice parameters associated with development of acute respiratory distress syndrome (ARDS) has not been extensively studied. We hypothesized a change in anesthesia machines would be associated with parameters associated with lower rates of ARDS. Methods: We […]
Read MoreRoger Chou, MD, Charles E. Argoff, MD Editor’s Note: As part of its effort to facilitate responsible opioid prescribing, the American Academy of Addiction Psychiatry(AAAP) hosts a listserv where clinicians can submit clinical questions and receive responses from a rotating panel of pain experts. In conjunction with the AAAP, Medscape has selected 10 of the […]
Read MoreI wanted to share this due to we might see these patients in surgery. Authors: Romero-Gómez M et al., J Hepatol 2015 Feb 62:437 This review article stresses the importance of providing intensive care, identifying precipitating events, and administering selective treatments. Hepatic encephalopathy (HE) is one of the major complications of cirrhosis, and recent evidence […]
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