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Authors: Johnson NJ et al., Resuscitation 2014 Sep 6; A small registry study adds to the growing body of literature showing feasibility of ECLS. Extracorporeal life support (ECLS) has been used as a rescue strategy for patients who do not respond to standard resuscitation. Investigators report outcomes for 26 adults who received ECLS for out-of-hospital, […]
Read MoreSeveral years ago, a California study showed that a half-dozen elective surgeries were being performed far more often in Humboldt County than they were in the rest of the state. The procedures included hip and knee replacements, hysterectomies and carotid endarterectomies, a surgery to remove plaque buildup in the carotid arteries. Geographical variation in the […]
Read MoreThis is for our chronic pain providers who might order NSAIDS. Published in J Allergy Clin Immunol Pract 2014 Jul/Aug 2:414 Authors: Aun MV et al. Epinephrine is first-line treatment for drug-induced anaphylaxis, but it is underutilized. Anaphylaxis is a life-threatening hypersensitivity reaction that can be allergic or nonallergic. Allergic causes of drug-induced anaphylaxis generally […]
Read MoreAuthors: Stiell IG et al., Circulation 2014 Sep 24; A large prehospital study found that survival was highest when chest compression depths were between 4.0 and 5.5 cm. In 2010, the American Heart Association (AHA) suggested an increase in the target depth of chest compressions to at least 5 cm. However, there have been no large clinical […]
Read MorePublished in Anesthesiology on 02 2015. Authors: Michael P. Eaton, M.D. et al Background: Antifibrinolytic medications such as ε-aminocaproic acid (EACA) are used in pediatric heart surgery to decrease surgical bleeding and transfusion. Dosing schemes for neonates are often based on adult regimens, or are simply empiric, in part due to the lack of neonatal pharmacokinetic information. […]
Read MorePublished in Anesthesiology on 03 2015 Authors: Jean Guglielminotti, M.D., Ph.D. Background: Individual assessment of the amplitude of a physiologic reflex evoked by a standardized noxious test (SNT) before surgical stimulation has been suggested to predict movement upon the forthcoming surgical stimulation. This study aimed to compare the ability of pupillary dilatation reflex amplitude (PDRA) evoked by […]
Read MorePublished in Anesthesiology on 03 2015 Authors: Jean Guglielminotti, M.D., Ph.D. Background: The rate of anesthesia-related adverse events (ARAEs) is recommended for monitoring patient safety across hospitals. To ensure comparability, it is adjusted for patients’ characteristics with logistic models (i.e., risk adjustment). The rate adjusted for patient-level characteristics and hospital affiliation through multilevel modeling is suggested as […]
Read MorePublished in Anesthesiology in 03 2015. Authors: Ajay Sampat, M.D. et al Background: Radical prostatectomy (RP) is most commonly performed laparoscopically with a robot (robotic-assisted laparoscopic radical prostatectomy, R/PROST). Hysterectomy, which may be open hysterectomy (O/HYST) or laparoscopic hysterectomy (L/HYST), has been increasingly frequently done via robot (R/HYST). Small case series suggest increased corneal abrasions (CAs) with less invasive […]
Read MorePublished in Anesthesiology in 03 2015 Authors: Oressia H. Zalucki, B.Sc., B.A. et al Background: Recent evidence suggests that general anesthetics activate endogenous sleep pathways, yet this mechanism cannot explain the entirety of general anesthesia. General anesthetics could disrupt synaptic release processes, as previous work inCaenorhabditis elegans and in vitro cell preparations suggested a role for the soluble NSF attachment […]
Read MoreAuthors: Susan M. Goobie, M.D., F.R.C.P.C. et al Published in Anesthesiology 2 2015. Background: Craniosynostosis surgery is associated with clinically significant postoperative events requiring intensive care unit (ICU) admission. The authors investigate specific variables, which might influence the risk for these events, and thereby make recommendations regarding the need for postoperative ICU admission. Methods: A retrospective review of […]
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