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Published in Paediatr Anaesth. 2014 Nov;24(11):1185-7 Authors: August DA et al We report the effects of 88 μg·kg(-1) of epinephrine (1:10,000) injected into the caudal epidural space of a 42-week postconceptual age infant. No long-term neurological or cardiovascular sequelae occurred. Noninvasive cardiac output (CO) monitoring revealed increased CO, contractility, and stroke volume for about an hour, […]
Read MorePublished in Anesthesiology 2014 Nov. Authors: Sonny A et al. A retrospective study suggests no association. Does carotid artery stenosis predispose patients who undergo noncardiac, noncarotid surgery to perioperative stroke? To find out, Cleveland Clinic researchers performed this retrospective study. During a 5-year period, 2110 patients who underwent noncardiac surgery had carotid duplex ultrasonography performed within […]
Read MorePublished in Acta Anaesthesiol Scand. 2015 Feb;59(2):224-31 Authors: Choi GJ et al BACKGROUND: This study aimed to compare emergence agitation following sevoflurane and desflurane anaesthesia in adults undergoing orthognathic surgery. The hypothesis was that there might be a difference in the incidence of emergence agitation following sevoflurane and desflurane anaesthesia considering the difference in blood solubility […]
Read MorePublished in Anesthesiology. 2015 Jan;122(1):140-9 Authors: Khodayari-Rostamabad A et al BACKGROUND: The authors investigated the effect of remifentanil administration on resting electroencephalography functional connectivity and its relationship to cognitive function and analgesia in healthy volunteers. METHODS: Twenty-one healthy male adult subjects were enrolled in this placebo-controlled double-blind cross-over study. For each subject, 2.5 min of multichannel […]
Read MoreChondroitin sulfate plus glucosamine is comparable to celecoxib in reducing pain in patients with knee osteoarthritis and is a safe alternative for patients with cardiovascular or gastrointestinal conditions who have contraindications to celecoxib. The findings were presented here at the 2014 Annual Scientific Meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals (ACR/ARHP) […]
Read MorePublished in Paediatr Anaesth. 2014 Nov;24(11):1149-57 Authors: Olischar M et al BACKGROUND: Tramadol is used following neonatal cardiac and general surgery. However, its ability to opioid-spare or facilitate earlier extubation in postoperative neonates is unquantified. OBJECTIVE: This randomized placebo-controlled trial aimed to assess whether tramadol’s addition to standard analgesia resulted in earlier extubation or reduced analgesic/sedative […]
Read MorePublished in Acta Anaesthesiol Scand. 2015 Feb;59(2):265-7. Authors: Pedersen AB et al Green urine from propofol infusion is a benign and rare side effect. The discolouration appears when clearance of propofol exceeds hepatic elimination, and extrahepatic elimination of propofol occurs. This case report presents a 24-year-old male with grass green discolouration of urine based on propofol […]
Read MoreThe US Food and Drug Administration (FDA) has approved extended-release hydrocodone bitartrate (Hysingla ER), an opioid analgesic to treat pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. Hydrocodone bitartrate ER has properties that are expected to reduce, but not totally prevent, abuse of the drug […]
Read MoreThis is for our pain providers. Researchers have found that current evidence does not support the routine use of minimally invasive surgery to remove herniated disc material pressing on the nerve root or spinal cord in the neck or lower back. In comparing it with open surgery, researchers found that while minimally invasive surgery for […]
Read MoreHealthy liver donors may be at increased risk for blood clots after hepatectomy, Japanese researchers have found. The retrospective study looked at 55 adult donors, all from the University of Tokyo Hospital, and found that hepatectomy influenced coagulation status, especially in the extrinsic pathway of coagulation. According to the study, one-third of the healthy liver […]
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