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Prolonged-release oxycodone / naloxone shows significant efficacy for the reduction of musculoskeletal pain and nocturnal pain for patients with severe pain from Parkinson’s disease compared with placebo, according to results of a double-blind study presented at the First Congress of the European Academy of Neurology (EAN). Prolonged-release oxycodone / naloxone also demonstrated no unanticipated adverse […]
Read MoreThe combination of peri-articular and adductor canal infiltration was superior than peri-articular infiltration alone or adductor canal infiltration alone in decreasing pain when walking on day 1 after a knee replacement, according to a study presented here at the 2015 Annual Meeting of the Canadian Anesthesiologists’ Society (CAS). “Knee surgery is very painful,” said Richard […]
Read MoreThe use of sumatriptan decreases post-operative headache at the non-surgical site in patients who undergo craniotomy for the treatment of trigeminal neuralgia and facial spasms, researchers said here at the 2015 Annual Meeting of the Canadian Anesthesiologists’ Society (CAS). “These patients complain of pain at the non-surgical site as well as nausea and vomiting,” said […]
Read MorePatients who minimally used opioids prior to surgery, but who continued to use them for pain relief 30 days after surgery were likely to be using them in the longer term, according to a study presented here at the 2015 Annual Meeting of the Canadian Anesthesiologists’ Society (CAS). With ongoing opioid use being a public […]
Read MoreSumatriptan is less effective in migraine attacks with aura than in those without, new data reveal. The findings, from an analysis of previous clinical trial results, were presented here at the American Headache Society (AHS) 57th Annual Scientific Meeting by Jakob Møller Hansen, MD, PhD, a resident at the Department of Neurology at Rigshospitalet and […]
Read MoreFentanyl 50 and 100 mcg is useful in accelerating the onset of labour analgesia without compromising safety, according to a study presented here at the 2015 Annual Meeting of the Canadian Anesthesiologists’ Society (CAS). “We have been decreasing our concentrations of our local anaesthetics, and we find that one of the impacts of that is […]
Read MoreThe use of periarticular ketorolac, an anti-platelet agent, does not produce additional blood loss in patients undergoing total knee arthroplasty (TKA), a retrospective study presented here at the annual meeting of the Canadian Anesthesiologists’ Society concludes. The study compared 57 patients who received periarticular ketorolac injection and 33 patients who didn’t (controls). Because ketorolac is […]
Read MoreActa Anaesthesiol Scand, 2015 Jun 4. doi: 10.1111/aas.12560 Authors: Xiao Y et al BACKGROUND: Tolerance to remifentanil during sevoflurane anesthesia may increase postoperative analgesic requirements. Low-dose naloxone not only has been shown to block the development of acute opioid tolerance but also to ameliorate undesired opioid-induced side effects. We hypothesized that naloxone prevents the acute opioid tolerance […]
Read MoreActa Anaesthesiol Scand. 2015 Jun 16. doi: 10.1111/aas.12571. Authors: Minoshima R et al BACKGROUND: In this randomized controlled trial, we examined whether intra- and postoperative infusion of low-dose ketamine decreased postoperative morphine requirement and morphine-related adverse effects as nausea and vomiting after scoliosis surgery. METHODS: After IRB approval and informed consent, 36 patients, aged 10-19 years, undergoing posterior […]
Read MoreNearly half of children and adolescents who present for the first time with migraine or probable migraine receive no treatment, and fewer than one in six receive evidence-based treatment, a new study finds. The results, from an analysis of electronic health record data across practice settings in four US states, were presented here at the […]
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