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Combining morphine and nortriptyline has been found to successfully relieve chronic neuropathic pain in 87% of patients, and significantly better than with either drug alone, according to a study published in the journal Pain. “Chronic pain is an increasingly common problem and can exert disastrous personal, societal, and socio-economic impacts on patients, their families, and […]
Read MoreNeonatal abstinence syndrome (NAS) has historically been associated with illicit drug use among pregnant women. However, a study published in the April issue of the journal Pediatrics showed an increased likelihood of NAS among pregnant women were narcotic pain relievers such as hydrocodone. In addition, the study found that opioid type and duration of exposure […]
Read MorePublished in Anesthesia & Analgesia April 2015 Authors: Subramanyam, Rajeev MBBS, DNB, MNAMS, MD, MS et al v BACKGROUND: Dexmedetomidine (Dex) appears to be very effective as a sole sedative for pediatric imaging when used at high doses, but at an increased risk of transient hypertension, hypotension, and bradycardia. There are no clinical evidence/guidelines to […]
Read MoreAuthors: Roberts E et al., Ann Rheum Dis 2015 Mar 2; In a review of observational studies, acetaminophen was associated with elevated risks for death and other adverse events. Acetaminophen generally is considered to be safer than nonsteroidal anti-inflammatory drugs and other commonly used analgesics, but randomized controlled trial–level data to support this idea are limited. To […]
Read MoreA Retrospective Comparative Cohort Study Authors: Hasan M Al-Dorzi et al Published in BMC Anesthesiol. 2014;14(126) Background Older age is associated with chronic illnesses and disability, which contribute to increased admission to the intensive care unit (ICU). Our primary objective was to compare the characteristics, ICU management and outcomes of critically ill patients ≥ 80 year-old with […]
Read MoreAn augmented approach to perioperative fluid management of complex surgical patients can lower the risk for postoperative morbidity by up to 29% and reduce health care costs by up to $970 per patient. The projections (Crit Care 2014;18:566) are based on a combination of actual clinical and cost data from the University HealthSystem Consortium (UHC) and […]
Read MorePublished in Int J Gynecol Cancer 2015 Jun;25(5):937-41 Authors: Hutchins J et al OBJECTIVE: We sought to determine the effect of a subcostal transversus abdominis plane (TAP) block with liposomal bupivacaine on postoperative maximal pain score and length of hospital stay among women undergoing robotic-assisted hysterectomy. METHODS: This was a retrospective study comparing patients before and after […]
Read MoreThe marked increase in the prevalence of obesity over the past 20 years has led to an increase in the number of bariatric and nonbariatric surgeries in this population. This in turn makes every anesthesiologist likely to deal with this challenging population. Perioperative targeted and organized assessment and preparation are important to reduce mortality and […]
Read MorePreoperative aspirin administration decreases postoperative acute kidney injury and mortality in patients with chronic kidney disease undergoing cardiac surgery, a study finds. “In previous studies, we found that aspirin pretreatment before surgery reduces perioperative complications and mortality in patients undergoing cardiac surgery,” said Jian-Zhong Sun, MD, PhD, professor of anesthesiology at Thomas Jefferson University, in […]
Read MorePublished in Anesthesiology 7 2015, Vol.123, 136-147. Authors: Chin-Chen Chu, MD, PhD et al Background: The effects of the mode of anesthesia on major adverse postoperative outcomes in geriatric patients are still inconclusive. The authors hypothesized that a neuraxial anesthetic (NA) rather than a general anesthetic (GA) would yield better in-hospital postoperative outcomes for geriatric patients undergoing […]
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