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Clin J Am Soc Nephrol, 2015 Sep 4. Authors: Leite TT et al BACKGROUND AND OBJECTIVES: Propofol has been shown to provide protection against renal ischemia/reperfusion injury experimentally, but clinical evidence is limited to patients undergoing cardiac surgery. There are no data about its association with oliguria and AKI in critically ill patients. DESIGN, SETTING, PARTICIPANTS, & […]
Read MorePain Med 2015 Aug 25 Authors: Morton TL et al OBJECTIVE: To correlate abuse-related pharmacodynamic measures and pharmacokinetic measures after administering immediate-release/extended-release and immediate-release oxycodone/acetaminophen fixed-dose combination analgesics DESIGN: Randomized, double-blind, active- and placebo-controlled, 7-way crossover study SETTING: Contract research organization SUBJECTS: Nondependent recreational users of prescription opioids. METHODS: Participants received single doses of intact immediate-release/extended-release and […]
Read MoreIr J Med Sci 2015 Sep 2. Authors: Baykal Tutal Z et al BACKGROUND AND AIMS: In this study, we compared duration for reaching desired Ramsay Sedation Score (RSS) and postoperative recovery according to Modified Aldrete Score (MAS) of propofol and propofol-ketamine combination in a group of colonoscopy patients. Rates of cardiovascular, respiratory, laryngospasm, visual and nausea/vomiting […]
Read MoreJ Pain Symptom Manage 2015 Nov;50(5):579-86 Authors: Mercadente S et al Fentanyl products have shown superiority to oral opioids for the management of breakthrough cancer pain (BTcP). However, these studies did not use appropriate patient selection, and drugs have been compared by using different rationales. OBJECTIVES: The aim of this randomized, crossover, controlled study was to compare […]
Read MorePublished in Eur Arch Otorhinolarygol, 2015 Sep;272(9):2193-9 Authors: Gungor G, et al Abstract Otoacoustic emissions (OAEs) are non-invasive, easy to apply and objective test methods which are widely used to determine the presence of hearing in audiology clinics. Under certain circumstances, the study should be applied under general anesthesia. The aim of this study was to determine […]
Read MoreOtolaryngol Head Neck Surg, 2015 Aug 18. Authors: Stephen MC et al OBJECTIVES: To evaluate the efficacy and safety of intranasal midazolam and chloral hydrate syrup for procedural sedation in children. STUDY DESIGN: Prospective randomized placebo-controlled trial (double blind, double dummy). SETTING: Tertiary care hospital over 18 months. SUBJECTS AND METHODS: Eighty-two children, 1 to 6 years […]
Read MoreAnesthesia & Analgesia: November 2015 Volume 121 Issue 5 p 1187-1193 Authors: Hori, Daijiro MD et al BACKGROUND: Individualizing mean arterial blood pressure (MAP) based on cerebral blood flow (CBF) autoregulation monitoring during cardiopulmonary bypass (CPB) holds promise as a strategy to optimize organ perfusion. The purpose of this study was to evaluate the accuracy […]
Read MoreAnesthesia & Analgesia: November 2015 Volume 121 Issue 5 p 1231-1239 Authors: Bender, S. Patrick MD et al BACKGROUND: The use of an intraoperative lung-protective ventilation strategy through tidal volume (TV) size reduction and positive end-expiratory pressure (PEEP) has been increasingly investigated. In this article, we describe the current intraoperative lung-protective ventilation practice patterns and […]
Read MoreAnesthesia & Analgesia: November 2015 Volume 121 Issue 5 p 1308-1315 Authors: Hauber, John A. BS et al BACKGROUND: Administration of dexmedetomidine (DEX) in the pediatric population for its sedative, analgesic, and anxiolytic properties has been widely reported, despite there being no label indication approved by the U.S. Food and Drug Administration for pediatric patients. […]
Read MoreIn carefully selected patients, minimally invasive surgery is enabling physicians to stop strokes in their tracks. As more patients undergo such procedures, physicians are debating the best way to anesthetise them. Should patients be put under general anaesthesia or should they undergo conscious sedation? In the September, 2015 issue of the Journal of Stroke and […]
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