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Published in BMJ, 2015 May 14;350:h2102. Authors: Desai RJ et al OBJECTIVE: To provide absolute and relative risk estimates of neonatal abstinence syndrome (NAS) based on duration and timing of prescription opioid use during pregnancy in the presence or absence of additional NAS risk factors of history of opioid misuse or dependence, misuse of other substances, non-opioid […]
Read MoreThe walls have ears, as the saying goes, but so do sedated patients whose smartphones have been set to “record.” In a recently concluded malpractice trial, that fact not only cost a Maryland doctor some money but subsequently her job, as a June 23 story in the Washington Post reports. The case involved a Vienna, Virginia, man […]
Read MorePublished in J Clin Anesth. 2015 May 30. pii: S0952-8180(15)00148-8 Authors: Linganna RE et al STUDY OBJECTIVE AND DESIGN: The mechanism of action of commonly used general anesthetics is largely unknown. One hypothesized mechanism is through modulation of microtubule stability. Taxanes, a subset of chemotherapeutic drugs known to alter microtubule stability and commonly used to treat breast […]
Read MorePublished in Drugs Aging. 2015 Jun;32(6):419-26. Authors: Veal FC et al Abstract Persistent pain affects the elderly disproportionally, occurring in 50 % of elderly community-dwelling patients and 80 % of aged care residents. The management of pain in the elderly and frail patient is complicated because of the risks posed by changes in pharmacokinetics and pharmacodynamics, polypharmacy, and drug-disease […]
Read MoreLiposomal-encased bupivacaine (LEB) is a good, cost-effective medical choice for pain control after breast surgery. Valerie Lemaine, MD, MPH, an assistant professor of plastic surgery and the vice chair for research at Mayo Clinic College of Medicine, Rochester, Minn., reviewed her experience at the 32nd Annual Miami Breast Cancer Conference. She noted that the drug […]
Read MoreDespite obvious challenges in identifying appropriate candidates, mechanically ventilated patients can safely self-administer sedative medications using widely available infusion pumps, a research team has concluded. Although the researchers’ primary focus was not the efficacy of the patient-controlled sedation (PCS) system, they hope to delve deeper into outcomes in future studies. “For many years, the paradigm […]
Read MoreM-Irfan Suleman, MD All research for this report was undertaken while the author was: Assistant Professor of Anesthesiology Director of Pediatric Regional Anesthesia Department of Anesthesiology Arkansas Children’s Hospital and University of Arkansas for Medical Sciences Little Rock, Arkansas I describe here a new, modified, ultrasound-guided penile block for male pediatric patients undergoing circumcision. The […]
Read MoreIt appears that patients with tension-type headache (TTH) have relatively weak neck extension muscles, a new study shows. Researchers found that these patients are 26% weaker than controls with respect to neck extension muscles, that they have a 12% smaller extension/flexion ratio, and that they have a borderline significant difference in the ability to generate […]
Read MorePublished in J Neurosurg. 2015 Apr 24:1-15. Authors: Hervey-Jumper SL et al OBJECT Awake craniotomy is currently a useful surgical approach to help identify and preserve functional areas during cortical and subcortical tumor resections. Methodologies have evolved over time to maximize patient safety and minimize morbidity using this technique. The goal of this study is to […]
Read MorePublished in World Neurosurgery April 2015 Authors: Chivukula S et al BACKGROUND The role for nucleus caudalis (NC) and spinal dorsal root entry zone (DREZ) lesioning in the management of chronic pain emanating from increased electrical activity in the dorsal horn of the spinal cord and brainstem remains largely uncharted. METHODS All patients that underwent […]
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