Children routinely face prolonged periods without eating or drinking before surgery, often extending hours beyond recommended guidelines, a new study has found. More than three-fourths of children who had surgery went more than 12 hours without solids before their operations, researchers at Boston Children’s Hospital reported. The study, which examined the records of more than […]
Read MoreActa Anaesthesiol Scand. 2015 May 5. doi: 10.1111/aas.12521. Authors: Kurita GP et al BACKGROUND: Renal impairment and the risk of toxicity caused by accumulation of opioids and/or active metabolites is an under-investigated issue. This study aimed at analysing if symptoms/adverse effects in opioid-treated patients with cancer were associated with renal function. METHODS: Cross-sectional multicentre study (European Pharmacogenetic […]
Read MoreActa Anaesthesiol Scand. 2015 April;59(7):921-7 Authors: Marashi SM et al BACKGROUND: In this study, the effect of naloxone on duration of supraclavicular brachial plexus block was evaluated. It was hypothesized that naloxone can increase the duration of neural blockade. METHODS: Sixty-eight patients scheduled for surgery under supraclavicular brachial plexus block were randomly assigned to receive 30 ml bupivacaine […]
Read MoreAnesthesia & Analgesia: June 2015 Vol 120 Issue 6 p 1405-1412 Authors: Hausman, Mark S. Jr. MD et BACKGROUND: Surgical patients with chronic obstructive pulmonary disease (COPD) are at increased risk of perioperative complications. In this study, we sought to quantify the benefit of avoiding general anesthesia in this patient population. METHODS: Data from the […]
Read MoreAnesthesia & Analgesia: June 2015 Vol 120 Issue 6 p 1369-1374 Authors: Radvansky, Brian M. BA et al BACKGROUND: Expert witnesses serve a crucial role in the medicolegal system, interpreting evidence so that it can be understood by jurors. Guidelines have been established by both the legal community and professional medical societies detailing the expectations […]
Read MoreAnesthesia & Analgesia: June 2015 Vol 120 Issue 6 p1352-1360 Authors: Malcharek, Michael J. MD et al BACKGROUND: Methods for detecting intraoperative cerebral ischemia arising from internal carotid artery (ICA) cross-clamping during carotid endarterectomy (CEA) should be sensitive, specific, and rapid to prevent intraoperative stroke. We had 3 objectives pertaining to this: (1) investigation of […]
Read MoreAnesthesia & Analgesia: June 2015 Vol 120 Issue 6 p 1325-1330 Authors: Duma, Andreas MD et al BACKGROUND: Prolonged administration of nitrous oxide causes an increase in plasma homocysteine in children via vitamin B12 inactivation. However, it is unclear whether nitrous oxide doses used in clinical practice cause adverse hematological effects in pediatric patients. METHODS: This […]
Read MoreAnesthesia & Analgesia: June 2015 Volume 120 Issue 6 p1273-1285 Authors: Correa, Denis MBBS, MD et al BACKGROUND: Chronic opioid use has been associated with the development of sleep-disordered breathing (SDB) such as central sleep apnea (CSA). Patients receiving chronic opioids may suffer from unrecognized sleep apnea that contributes to opioid-overdose death. Currently, information regarding […]
Read MoreAnesthesia & Analgesia: June 2015 Volume 120 Issue 6 o 1214-1224 Postoperative Sleep-Disordered Breathing in Patients Without Preoperative Sleep Apnea Authors: Chung, Frances MBBS, FRCPC et al BACKGROUND: Recently published data show that postoperative apnea-hypopnea index (AHI) is significantly increased in some patients without preoperative sleep apnea. These patients may be at risk of developing […]
Read MorePublished in JAMA Facial Plast Surg, 2015 Jul 1;17(4):251-5. Authors: Trimas SJ et al IMPORTANCE: Patients who experience immediate postoperative nausea and vomiting (PONV) after their facial plastic surgery procedure have a higher incidence of complications and dissatisfaction. OBJECTIVES: To determine whether a single dose of aprepitant administered preoperatively can decrease the incidence of immediate PONV in […]
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