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Published in World Neurosurgery April 2015 Authors: Chivukula S et al BACKGROUND The role for nucleus caudalis (NC) and spinal dorsal root entry zone (DREZ) lesioning in the management of chronic pain emanating from increased electrical activity in the dorsal horn of the spinal cord and brainstem remains largely uncharted. METHODS All patients that underwent […]
Read MorePublished in Spine Mar 2015 Authors: Darlow B. et al STUDY DESIGN Qualitative interview study Objective. Explore attitudes, beliefs, and perceptions related to low back pain (LBP), and analyze how these might influence the perceived threat associated with back pain. SUMMARY OF BACKGROUND DATA Psychological factors which contribute to the perceived threat associated with LBP […]
Read MorePeople with insomnia and other sleep problems have increased sensitivity to pain, according to a study published in the journal Pain. The effect on pain tolerance appears strongest in people who suffer from both insomnia and chronic pain, who may benefit from treatments targeting both conditions. The study included more than 10,400 adults from a […]
Read MoreJ Pain 2015 Jul;16(7):666-75. Authors: Bruehl S et al Abstract The Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R) predicts increased risk of opioid misuse in chronic pain patients. We evaluated whether higher SOAPP-R scores are associated with greater opioid reinforcing properties, potentially contributing to their predictive utility. Across 2 counterbalanced laboratory sessions, 55 chronic low […]
Read MoreBMJ. April 2015; 350: h1640. Authors: Kerstin Luedtke postdoctoral researcher, et al Objective To evaluate the effectiveness of transcranial direct current stimulation alone and in combination with cognitive behavioural management in patients with non-specific chronic low back pain. Design Double blind parallel group randomised controlled trial with six months’ follow-up conducted May 2011-March 2013. Participants, physiotherapists, assessors, and […]
Read MoreJ Pediatr 2015 May;166(5):1226-32 Authors: Belmont AP et al OBJECTIVE: To assess the rates and types of complications associated with deep sedation in children with sickle cell disease (SCD) and to explore potential risk factors. STUDY DESIGN: This was a retrospective cohort study of children with SCD and a comparison group of children without SCD who underwent […]
Read MoreMedicine (Baltimore) 2015 Apr;94(14):e597 Authors: Li B et al Abstract Many studies have reported the beneficial effects of dexmedetomidine on postoperative neurocognitive function but overall evidence is not as clear. We examined this conundrum by meta-analyzing studies that used dexmedetomidine in perioperative conditions or as intensive care unit (ICU) sedation and utilized reliable neurocognitive assessment tests. The […]
Read MoreThe US Food and Drug Administration has approved fentanyl iontophoretic transdermal system (Ionsys, The Medicines Co), the first needle-free, patient-controlled, preprogrammed fentanyl delivery system for management of acute postoperative pain in adults requiring opioid analgesia in the hospital, according to a company news release. Ionsys is a “novel alternative” to traditional intravenous patient-controlled analgesia that uses […]
Read MoreWorld J Gastroenterol 2015 Mar 28;21(12):3671-8. Authors: Kim N et al AIM: To compare the efficacy and safety of sedation protocols for endoscopic submucosal dissection (ESD) between dexmedetomidine-remifentanil and propofol-remifentanil. METHODS: Fifty-nine patients scheduled for ESD were randomly allocated into a dexmedetomidine-remifentanil (DR) group or a propofol-remifentanil (PR) group. To control patient anxiety, dexmedetomidine or propofol was […]
Read MoreActa Anaesthesiol Scand 2015 Apr 21 Authors: Heid F et al BACKGROUND: Pelvic intraoperative neuromonitoring (pIONM) aims to identify and spare the autonomic nerves and maintain patients’ quality of life. The effect of anaesthetic agents on the pIONM signal is unknown; therefore, the aim of the present study was to compare the influences of inhalation anaesthesia (IA) […]
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