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Anesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 1147–1152 AUTHORS: Gulec, Ersel MD et al BACKGROUND: Dexamethasone has been shown to cause inhibition of sugammadex reversal in functionally innervated human muscle cells. In this prospective, double-blind, randomized, controlled study, we evaluated the effect of dexamethasone on the reversal time of […]
Read MoreOn April 15, as part of the American Society of Anesthesiologists’ broader advocacy strategy to increase federal funding for anesthesia and pain medicine research, ASA submitted a written statement for the formal record of the House Appropriations Subcommittee on Labor, Health and Human Services, Education and Related Agencies on the need for federal investment in […]
Read MoreAnesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 1101–1107 AUTHORS: Khandelwal, Nita MD, MS et al BACKGROUND: Based on the data from elective surgical patients, positioning patients in a back-up head-elevated position for preoxygenation and tracheal intubation can improve patient safety. However, data specific to the emergent setting are lacking. […]
Read MoreAnesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 1132–1140 AUTHORS: Görges, Matthias PhD et al BACKGROUND: Respiratory depression in children receiving postoperative opioid infusions is a significant risk because of the interindividual variability in analgesic requirement. Detection of respiratory depression (or apnea) in these children may be improved with the […]
Read MoreAnesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 1120–1129 AUTHORS: Kuhn, Jana Christine MD et al BACKGROUND: Phenylephrine infusion is the current first-line choice for prevention of spinal hypotension during cesarean delivery. The optimal dosage regimen is still undetermined. A mechanical alternative, lower limb wrapping, has been examined in a […]
Read MoreAnesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 1081–1088 AUTHORS: Geube, Mariya A. MD et al BACKGROUND: Severe primary graft dysfunction (PGD) is a major cause of early morbidity and mortality in patients after lung transplantation. The etiology and pathophysiology of PGD is not fully characterized and whether intraoperative fluid […]
Read MoreAnesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 1114–1119 AUTHORS: Booth, Jessica L. MD et al BACKGROUND: Improved pain control after cesarean delivery remains a challenging objective. Poorly treated acute pain following delivery is associated with an increased risk of chronic pain and depression. This study was conducted to determine […]
Read MoreAnesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 1070–1078 AUTHORS: Applegate, Richard L. II MD et al BACKGROUND: Diagnostic and interventional procedures are often facilitated by moderate procedure-related sedation. Many studies support the overall safety of this sedation; however, adverse cardiovascular and respiratory events are reported in up to 70% […]
Read MoreAnesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 1062–1069 AUTHORS: Boyer, Richard B. PhD et al BACKGROUND: Rapid infusers are vital tools during massive hemorrhage and resuscitation. Sporadic reports of overheating and shutdown of the Belmont® Rapid Infuser, a commonly used system, have been attributed to 1-sided clot blockage of […]
Read MoreAnesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 1024–1030 AUTHORS: Yuan, Jing MD et al BACKGROUND: It has been increasingly suggested that propofol protects against hypoxic-/ischemic-induced neuronal injury. As evidenced by hemorrhage-induced stroke, hemorrhage into the brain may also cause brain damage. Whether propofol protects against hemorrhage-induced brain damage remains […]
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