Author: Dr Clemens

Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial

Lancet. 2015 Oct 23. pii: S0140-6736(15)00608 Authors: Davidson AJ et al BACKGROUND: Preclinical data suggest that general anaesthetics affect brain development. There is mixed evidence from cohort studies that young children exposed to anaesthesia can have an increased risk of poor neurodevelopmental outcome. We aimed to establish whether general anaesthesia in infancy has any effect on […]

Avoid Sedatives and Opioids for Treating Low Back

Perioperative Surgical Home Improves Quality, Reduces Costs

With the perioperative surgical home model — in which an anesthesiologist manages a patient’s surgical experience in collaboration with the patient, the patient’s family, and other healthcare providers — hospital stays are shorter and rates of discharge home are higher, according to a new study. The findings show that the program has a promising future beyond its […]

Low-dose Ketamine Eases Pain, Reduces Opioid Use in ED

I thought this was interesting so I wanted to share it with our readers. The use of low-dose ketamine as an adjunct to opioids for pain control in the emergency department led to reductions in pain scores, total opioid dosing, and frequency of opioid dosing, results from a randomized, placebo-controlled trial indicate. “The reduced frequency […]

Intraoperative Lung-Protective Ventilation Trends and Practice Patterns: A Report from the Multicenter Perioperative Outcomes Group

Anesthesia & Analgesia:November 2015 – Volume 121 – Issue 5 – p 1231–1239 Authors: Patrick MD et al BACKGROUND: The use of an intraoperative lung-protective ventilation strategy through tidal volume (TV) size reduction and positive end-expiratory pressure (PEEP) has been increasingly investigated. In this article, we describe the current intraoperative lung-protective ventilation practice patterns and […]

The Impact of Anesthetic Management on Surgical Site Infections in Patients Undergoing Total Knee or Total Hip Arthroplasty

Anesthesia & Analgesia: Nov 2045 Vol 121 zissue 5 p1215-1221 Authors: Kopp, Sandra L. MD et al BACKGROUND: Surgical site infection (SSI) is one of the most challenging and costly complications associated with total joint arthroplasty. Our primary aim in this case-controlled trial was to compare the risk of SSI within a year of surgery […]

A Randomized Controlled Trial Comparison of NeuroSENSE and Bispectral Brain Monitors During Propofol-Based Versus Sevoflurane-Based General Anesthesia

Anesthesia & Analgesia: Nov 2015 Vol 121 issue 5 p 1194-1201 Authors: Bresson Julie MD et al BACKGROUND: NeuroSENSE is a depth of anesthesia monitor that uses automated electroencephalogram quantification. The Wavelet-based Anesthetic Value for Central Nervous System (WAVCNS) index calculated by this monitor is based on wavelet analysis of a normalized electroencephalogram signal in […]

Intrapleural migration of a spinal catheter in a patient with arachnoiditis and extensive epidural scarring after tethered cord release: a case report and review of literature

The objective of this study was to report a case of new onset refractory pain from intrapleural migration of a spinal catheter five months after the implantation of an intrathecal drug delivery system (IDDS). A 57-year-old man had intractable pain because of multiple intradural spinal explorations for tethered cord release. His pain was effectively treated […]

Propofol Provides More Effective Protection for Circulating Lymphocytes Than Sevoflurane in Patients Undergoing Off-Pump Coronary Artery Bypass Graft Surgery

J Cardiothorac Vasc Anesth 2015 Oct;29(5):1172-9. Authors: Jia L et al OBJECTIVE To compare the effects of propofol, sevoflurane, and the combination of the 2 on circulating lymphocytes in patients undergoing off-pump coronary artery bypass graft (OPCAB) surgery. DESIGN: A prospective, randomized study. SETTING: A university hospital. PARTICIPANTS: One hundred five patients undergoing elective OPCAB surgery. […]

Inadvertent Hypothermia After Procedural Sedation and Analgesia in a Cardiac Catheterization Laboratory: A Prospective Observational Study

J Cardiothorac Vasc Anesth 2015 Oct;29(5):1285-90. Authors: Conway A et al OBJECTIVES: To identify the prevalence of and risk factors for inadvertent hypothermia after procedures performed with procedural sedation and analgesia in a cardiac catheterization laboratory. DESIGN: A single-center, prospective observational study. SETTING: A tertiary-care private hospital in Australia. PARTICIPANTS: 399 patients undergoing elective procedures with procedural […]