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Empty blood units piled on the operating room floor after a trauma. A large retrospective analysis has uncovered a previously unnoticed linear relationship between mortality and units of blood transfused, namely, that there is a 10% increase in mortality for every additional 10 units of blood transfused—what has been dubbed “the 50/50 rule.” Morbidities were […]
Read MoreVery Large Database Finds: Anesthesiologists are working harder to better understand preoperative risks that may influence perioperative care. According to one intriguing study of surgical risks, preoperative low blood pressure—as opposed to high blood pressure—is a risk factor for death. The study, conducted by researchers in the United States and United Kingdom, looked at data […]
Read MoreA collaborative, checklist-driven, multimodal protocol called the ComfortSafe anesthetic technique can provide effective postoperative pain relief and enhanced recovery after surgery (ERAS) while preventing complications associated with opioid analgesics. Getting anesthesiologists to adopt a less narcotic-heavy view of analgesia has become a crusade for one of the researchers who devised the protocol. “We’ve been using […]
Read MoreContinued use of beta-blockers for hypertension during noncardiac surgery can raise the risk of major adverse cardiac events (MACE) and all-cause mortality within 30 days in a relatively low-risk population, suggests new research that is in line with earlier studies that generally included higher-risk patients. A Danish cohort of more than 55,000 low-risk hypertension patients […]
Read MoreAnesth Analg 2015 Dec;121(6):1640-54. Authors: Baeriswyl M et al BACKGROUND: Previous meta-analyses of the transversus abdominis plane (TAP) block have examined a maximum of 12 articles, including fewer than 650 participants, and have not examined the effect of ultrasound-guided techniques specifically. Recently, many trials that use ultrasound approaches to TAP block have been published, which report conflicting […]
Read MoreI wish everyone and their family a very Merry Christmas!
Read MoreAuthors: Timothy J Wigmore, MA, FRCA FFICM FCICM et al Anesthesiology 1 2016, Vol.124, 69-79. Background: Surgical resection remains the best option for long-term survival in many solid tumors. Surgery can, however, lead to tumor cell release into the circulation. Data have suggested differential effects of anesthetic agents on cancer cell growth. This retrospective analysis investigated the association […]
Read MoreOverdose deaths from opioids — both prescription opioids and heroin — reached an all-time high in 2014, according to the CDC. Following a relative plateau around 16,000 deaths per year, prescription opioid overdose deaths shot up 16% in 1 year to 18,893 dealths in 2014 Rose Rudd, MSPH, of the CDC, and colleagues reported in Morbidity […]
Read MoreAuthors: Ishigaki S et al., Anesth Analg 2015 Nov 23; In a randomized trial, patients receiving rocuronium followed by a saline flush had an earlier onset of neuromuscular blockade than those receiving rocuronium alone. Reliable, rapid onset of neuromuscular blockade is critical for successful emergency rapid sequence intubation (RSI). Rocuronium has a slower onset than succinylcholine. The […]
Read MoreAuthors: Yannick Le Manach, MD, PhD Anesthesiology published on 12 2015. Background: An accurate risk score able to predict in-hospital mortality in patients undergoing surgery may improve both risk communication and clinical decision making. The aim of the study was to develop and validate a surgical risk score based solely on preoperative information, for predicting in-hospital mortality. […]
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