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Anesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 943–952 AUTHORS: Claudia Regina MD, PhD et al BACKGROUND: It is unclear whether maintaining pulmonary perfusion and ventilation during cardiopulmonary bypass (CPB) reduces pulmonary inflammatory tissue injury compared with standard CPB where the lungs are not ventilated and are minimally perfused. In […]
Read MoreAnesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 935–942 AUTHORS: Franklin, Sarah W. BA et al BACKGROUND: Bleeding is a serious complication after pediatric cardiopulmonary bypass (CPB) that is associated with an increase in perioperative morbidity and mortality. Four-factor prothrombin complex concentrates (4F-PCCs) have been used off-label to supplement transfusion […]
Read MoreAuthors: Spoletini G et al., JAMA 2016 Mar 15; High-flow oxygen and noninvasive positive pressure ventilation lowered reintubation rates in selected patient populations. During the past few years, interest has grown in using high-flow oxygen (HFO) and noninvasive positive pressure ventilation (NPPV) in lieu of intubation and mechanical ventilation (NEJM JW Gen Med Aug 1 […]
Read MoreAnesthesia & Analgesia: March 2016 AUTHORS: Buckley, Jack C. MD et al BACKGROUND: Endotracheal tube security is a critical safety issue. We compared the mobility of an in situ endotracheal tube secured with adhesive tape to the one secured with a new commercially available purpose-designed endotracheal tube-holder device (Haider Tube-Guard(R)). We also observed for the […]
Read MoreAnesthesia & Analgesia: March 2016 AUTHORS: Ghadimi, Kamrouz MD et al Prothrombin complex concentrates (PCCs) contain vitamin K-dependent clotting factors (II, VII, IX, and X) and are marketed as 3 or 4 factor-PCC formulations depending on the concentrations of factor VII. PCCs rapidly restore deficient coagulation factor concentrations to achieve hemostasis, but like with all […]
Read MoreWhether relating to health outcomes, patient perceptions of care or organizational structure, quality metrics are playing an increasingly substantive role in Medicare payment and reimbursement. As Robert S. Lagasse, MD, explained at the 2016 American Society of Anesthesiologists Practice Management annual meeting, despite the limitations of these measures, the financial stakes for physicians have never […]
Read MoreAnesthesia & Analgesia: March 2016 AUTHORS: Wang, Mi MD et al BACKGROUND: The nasopharynx is considered 1 of the 4 generally reliable core temperature measurement sites. But curiously, there is no consensus on how far past the nares to insert the probe. Insertion depth is likely to influence the accuracy of nasopharyngeal temperature measurements because […]
Read MoreGiven its prevalence after cardiac surgery—particularly in patients with chronic renal impairment—finding a way to curb postoperative acute kidney injury (AKI) stands to have a significant effect on patient outcomes. A Japanese research team seems to have taken a step in that direction; their study found that intraoperative administration of haptoglobin was independently associated with […]
Read MoreAnesthesia & Analgesia: March 2016 AUTHORS: Sviggum, Hans P. MD et al BACKGROUND: Intrathecal (IT) morphine is considered the “gold standard” for analgesia after cesarean delivery under spinal anesthesia, most commonly administered at a dose of 100 to 200 [mu]g. There is less experience with IT hydromorphone for postcesarean analgesia and limited information on its […]
Read MoreA Randomized Controlled Trial Authors: Mari Nagafuchi et al BMC Anesthesiol. 2015;15(182) Background: The use of femoral nerve block (FNB) combined with sciatic nerve block (SNB) after total knee arthroplasty (TKA) has recently become controversial. Local infiltration analgesia (LIA) has been reported to be effective for postoperative TKA pain control. We aimed to assess whether […]
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