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Anesthesia & Analgesia: April 15, 2016 AUTHORS: Zaphiratos, Valerie MD, MSc, FRCPC et al BACKGROUND: Combined spinal-epidural (CSE) analgesia is widely used for delivering labor analgesia. Epidural volume extension (EVE) involves the injection of fluid into the epidural space compressing the dural sac, causing cephalad shift of the cerebral spinal fluid. Our hypothesis was that […]
Read MoreAnesthesia & Analgesia: April 15, 2016 AUTHORS: Bang, Ji-Yeon MD, PhD et al BACKGROUND: Acute kidney injury (AKI) is a primary cause of morbidity and mortality after major abdominal surgery; however, little is known about the effect of anesthetics on the development of AKI after colorectal surgery. The objective of this study was to compare […]
Read MoreAuthors: M Narayanan MB BS MD FRCA FCARCSI EDIC EDRA et al BJA Education. 2016;16(2):72-78. Introduction Patients in intensive care experience distress because of a multitude of factors and a significant proportion is attributable to pain.[1] A vast majority of patients report moderate to severe pain at some point during their intensive care stay. Pain can be […]
Read MoreStudy finds fentanyl transdermal patches are too often prescribed to opioid-naïve and elderly patients, raising their risks of fatal adverse drug events. Interview with Caleb Alexander, MD Fentanyl patches are a highly potent options for cancer and non-cancer pain patients, but are contraindicated in opioid naïve patients. However, new research indicates that physicians may be […]
Read MoreAnesthesia & Analgesia: May 17, 2016 AUTHORS: Zentai, Christian MD et al BACKGROUND: The potential clinical benefits of targeted therapy with coagulation factor concentrates (e.g., fibrinogen) and antifibrinolytic agents (e.g., tranexamic acid [TXA]) for the treatment of trauma-induced coagulopathy are increasingly recognized. We hypothesized that human fibrinogen concentrate (FC) and prothrombin complex concentrate (PCC), administered […]
Read MoreBy now, one would think that all health care workers know the importance of washing their hands, yet a recent study found that staff at outpatient care facilities fail to follow recommendations for hand hygiene 37% of the time, and for safe injection practices 33% of the time, even after having policies in place about […]
Read MoreIn stark contrast to a 2010 investigation suggesting that nurse anesthetists frequently provide care unsupervised by physician anesthesiologists, researchers at the University of Texas Medical Branch and the American Society of Anesthesiology’s (ASA) Department of Health Policy have found that the Medicare billing code at the center of that trial—modifier QZ—does not seem to be […]
Read MoreThe American Pain Society, for the first time, has released a clinical practice guideline on managing postoperative pain. The guideline was created with input from the American Society of Anesthesiologists (ASA) and was subsequently approved by the American Society for Regional Anesthesia and Pain Medicine (ASRA), and was based on the 23-member panel’s review of […]
Read MoreAutopsy confirms that the pop star died of an accidental overdose of fentanyl. But questions remain regarding his pain treatment and recovery plans. Interview with Jeffrey Fudin, PharmD, DAAPM, FCCP, FASHPThe autopsy report confirms fentanyl in Prince’s system at the time of death. Since his death, news coverage has speculated about what caused Prince to […]
Read MoreAnesthesia & Analgesia: May 17, 2016 AUTHORS: Liou, Jing-Yang MD et al BACKGROUND: Selecting an effective dose of sedative drugs in combined upper and lower gastrointestinal endoscopy is complicated by varying degrees of pain stimulation. We tested the ability of 5 response surface models to predict depth of sedation after administration of midazolam and alfentanil […]
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