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Patients undergoing staged bilateral total knee arthroplasty (TKA) can gain greater relief from tertiary hyperalgesia if treated with magnesium sulphate, according to a study presented here at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO). “Administration of magnesium significantly reduced postoperative pain and the difference in pain intensity between the first and second […]
Read MoreA form of transcutaneous electrical neuro-stimulation is both effective and safe in relieving pain due to knee osteoarthritis, according to a study presented here at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO). Dynamic electrical neuro-stimulation delivers weak (200 to 400 mkA) and low frequency (10 to 200 Hz) pulses of electricity to […]
Read MoreMaternal use of pregabalin (Lyrica) might be associated with increased risk for birth defects in offspring, according to a small case-control study in Neurology. In the U.S., pregabalin is approved to treat numerous conditions, including neuropathic pain, seizures, and fibromyalgia. Researchers studied roughly 160 European women exposed to pregabalin during pregnancy and 660 unexposed controls. Excluding […]
Read MoreWomen with migraine face increased risk for cardiovascular events and CV mortality, according to a large prospective study in The BMJ. In the Nurses’ Health Study II, over 115,000 women aged 25 to 42 without angina or CV disease reported whether they’d ever been diagnosed with migraine and then were followed for roughly 20 years. Some […]
Read MoreAuthors: Bradley A. Fritz, M.D. et al Anesthesiology 6 2016, Vol.124, 1265-1276. Background: Anesthesiologists need tools to accurately track postoperative outcomes. The accuracy of patient report in identifying a wide variety of postoperative complications after diverse surgical procedures has not previously been investigated. Methods: In this cohort study, 1,578 adult surgical patients completed a survey at least […]
Read MorePatients using the sumatriptan iontophoretic transdermal patch (Zecuity) to treat migraines could be burned or permanently scarred, warns the FDA. The agency says it has received a “large number” of reports of skin reactions associated with the patch since it went on the market in September 2015. The patch — battery-powered and wrapped around the […]
Read MoreAuthors: J. Lance Lichtor, M.D. et al Anesthesiology 6 2016, Vol.124, 1404-1407. Due to the potentially unforgiving nature of epiglottitis and supraglottitis, the clinician should have a firm understanding of the presentation, work up, and management of a patient presenting with worrisome symptoms. George Washington, the United States’ first president, 2 yr after leaving office on […]
Read MoreAuthors: Christopher Uhlig, M.D. et al Anesthesiology 6 2016, Vol.124, 1230-1245. Background: It is not known whether modern volatile anesthetics are associated with less mortality and postoperative pulmonary or other complications in patients undergoing general anesthesia for surgery. Methods: A systematic literature review was conducted for randomized controlled trials fulfilling following criteria: (1) population: adult patients undergoing general […]
Read MoreThe FDA has approved a buprenorphine implant as a maintenance treatment for opioid dependence. Probuphine, made up of four inch-long rods placed subdermally on the inside of the upper arm, is designed to deliver a steady dose of buprenorphine over a 6-month period. The implant is approved for patients who are already on low-to-moderate doses […]
Read MoreOpioids commonly are used for pain management in patients with osteoarthritis. However, a new study has found that reducing opioid use by half prior to surgery may lead to better functional outcomes. By Thomas G. Ciccone and Forest Tennant, MD, DrPH Interview with Kevin J. Bozic, MD, MBA Managing pain from knee or hip osteoarthritis (OA) is oftentimes […]
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