Author: Dr Clemens

Uncategorized Published - 11 March, 2016    By - Dr Clemens
Continuous Lidocaine Infusions to Manage Opioid-Refractory Pain in a Series of Cancer Patients in a Pediatric Hospital

Pediatr Blood Cancer. 2016 Jan AUTHORS: Gibbons K et al BACKGROUND: Research on the safety and efficacy of continuous lidocaine infusions (CLIs) for the treatment of pain in the pediatric setting is limited. This article describes a series of pediatric oncology patients who received lidocaine infusions for refractory, longstanding, cancer-related pain. PROCEDURE: This is a retrospective […]

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Uncategorized Published - 10 March, 2016    By - Dr Clemens
The Effects of Ketamine on Cognitive Function in Elderly Patients Undergoing Ophthalmic Surgery: A Pilot Study

Anesth Analg. 2016 Jan AUTHORS: Rascón-Martínez DM et al BACKGROUND: Acute postoperative cognitive dysfunction is characterized by neurocognitive dysfunction and confusion. In this study, we compared the cognitive status of a geriatric population undergoing ophthalmic surgery, as assessed by the Short Portable Mental Status Questionnaire (SPMSQ) before and after ketamine administration. METHODS: Eighty patients were enrolled […]

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Uncategorized Published - 10 March, 2016    By - Dr Clemens
A prospective randomized comparative study of postoperative pain control using an epidural catheter in patients undergoing posterior lumbar interbody fusion

Eur Spine J. 2016 Jan AUTHORS: Park SY et al PURPOSE: To assess the efficacy of continuous epidural infusion analgesia (ED) with 0.2 % Ropivacaine versus IV PCA (Fentanyl) in spinal fusion surgery patients. METHOD: A prospective randomized comparative clinical trial. Patients were randomized into one of two groups-the epidural group (ED-51 patients) and the IV PCA […]

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Uncategorized Published - 10 March, 2016    By - Dr Clemens
An Evaluation of Ultrasound-Guided Adductor Canal Blockade for Postoperative Analgesia After Medial Unicondylar Knee Arthroplasty

Anesth Analg. 2016 Jan AUTHORS: Henshaw DS et al BACKGROUND: Unicondylar knee arthroplasty (UKA) is a commonly performed procedure with significant expected postoperative pain. Peripheral nerve blocks are 1 analgesic option, but some approaches may decrease quadriceps motor strength and interfere with early ambulation. In this study, we compared the analgesia provided by an adductor canal […]

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Uncategorized Published - 10 March, 2016    By - Dr Clemens
Dexmedetomidine Combined with General Anesthesia Provides Similar Intraoperative Stress Response Reduction When Compared with a Combined General and Epidural Anesthetic Technique

Anesthesia & Analgesia: January 2016 AUTHORS: D; Wang et al BACKGROUND: Epidural anesthesia may attenuate the sympathetic hyperactivity and stress response from surgery. In this study, we compared the stress response, hemodynamic variables, and recovery profiles of patients undergoing total IV anesthesia (TIVA) and intraoperative dexmedetomidine with those receiving epidural anesthesia and TIVA. METHODS: Ninety […]

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Uncategorized Published - 10 March, 2016    By - Dr Clemens
Increased Intraoperative Fluid Administration Is Associated with Severe Primary Graft Dysfunction After Lung Transplantation

Anesthesia & Analgesia: January 2016 AUTHORS: Geube, Mariya A. MD et al BACKGROUND: Severe primary graft dysfunction (PGD) is a major cause of early morbidity and mortality in patients after lung transplantation. The etiology and pathophysiology of PGD is not fully characterized and whether intraoperative fluid administration increases the risk for PGD remains unclear from […]

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Uncategorized Published - 9 March, 2016    By - Dr Clemens
Bradycardia as an Early Warning Sign for Cardiac Arrest During Routine Laparoscopic Surgery

Authors: Jonathan Yong et al Int J Qual Health Care. 2015;27(6):472-477. Objectives: The aim of this study was to identify clinical patterns of occurrence, management and outcomes surrounding cardiac arrest during laparoscopic surgery using the Australian Incident Monitoring Study (AIMS) database to guide possible prevention and treatment. Setting: The AIMS database includes incident reports from participating clinicians from […]

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Uncategorized Published - 9 March, 2016    By - Dr Clemens
The Feasibility of a Completely Automated Total IV Anesthesia Drug Delivery System for Cardiac Surgery.

Anesthesia & Analgesia: January 2016 AUTHORS: Zaouter, Cedrick MD et al BACKGROUND: In this pilot study, we tested a novel automatic anesthesia system for closed-loop administration of IV anesthesia drugs for cardiac surgical procedures with cardiopulmonary bypass. This anesthesia drug delivery robot integrates all 3 components of general anesthesia: hypnosis, analgesia, and muscle relaxation. METHODS: […]

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Uncategorized Published - 9 March, 2016    By - Dr Clemens
Anesthesia and Cognitive Decline: No Link?

There is no significant link between exposure to general anesthesia and the development of mild cognitive impairment (MCI) in individuals aged 40 years and older, a large, comprehensive, population-based study shows. The potential link between exposure to surgical anesthesia, MCI, and dementia has been a matter of recent debate, with previous research contradicting the current […]

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Uncategorized Published - 9 March, 2016    By - Dr Clemens
Inflammation and Organ Failure Severely Affect Midazolam Clearance in Critically Ill Children.

Am J Respir Crit Care Med. 2016 Jan 21 AUTHORS: Vet NJ et al RATIONALE: Various in vitro, animal and limited human adult studies suggest a profound inhibitory effect of inflammation and disease on Cytochrome P450 3A (CYP3A)-mediated drug metabolism. Studies showing this relationship in critically ill patients are lacking, while clearance of many CYP3A drug […]

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