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Authors: Laurent G. Glance, M.D. et al Anesthesiology published on September 29, 2016 Background: The validity of basing healthcare reimbursement policy on pay-for-performance is grounded in the accuracy of performance measurement. Methods: Monte Carlo simulation was used to examine the accuracy of performance profiling as a function of statistical methodology, case volume, and the extent to which hospital […]
Read MoreEdited by Susan Sadoughi, MD Individual nonsteroidal anti-inflammatory drugs (NSAIDs) are associated with increased risk for heart failure hospitalization, according to a large study in The BMJ. Using electronic health databases from four European countries, researchers identified 7.7 million adults who started taking prescription NSAIDs in 2000–2010. The 92,000 patients who were admitted for heart failure were […]
Read MoreAnesthesia & Analgesia: July 26, 2016 AUTHORS: Grant, Michael C. MD et al BACKGROUND: Nonopioid adjuvant medications are increasingly included among perioperative Enhanced Recovery After Surgery protocols. Preoperative pregabalin has been shown to improve postoperative pain and limit reliance on opioid analgesia. Our group investigated the ability of preoperative pregabalin to also prevent postoperative nausea […]
Read MoreAnesthesia & Analgesia: July 26, 2016 Authors: Petersen, Christian Leth PhD et al BACKGROUND: Recent research and advances in the automation of anesthesia are driving the need to better understand electroencephalogram (EEG)-based anesthesia end points and to test the performance of anesthesia monitors. This effort is currently limited by the need to collect raw EEG […]
Read MoreAnesthesia & Analgesia: July 26, 2016 AUTHORS: Karlsson, Victoria RN, MMSc BACKGROUND: Transcutaneous (TC) measurement of PCO2 (TC PCO2) is a well-established method to monitor assisted ventilation in neonatal intensive care, but its use in the operating room is limited, and the data regarding its performance during general anesthesia of the newborn are lacking. The […]
Read MoreAnesthesia & Analgesia: July 26, 2016 AUTHORS: Carvalho, Brendan MBBCh, FRCA, MDCH et al Programmed intermittent epidural bolus (PIEB) is an exciting new technology that has the potential to improve the maintenance of epidural labor analgesia. PIEB compared with a continuous epidural infusion (CEI) has the potential advantage of greater spread within the epidural space […]
Read MoreAnesthesia & Analgesia: July 22, 2016 AUTHORS: Kwon, Min-Ji BS et al BACKGROUND: Placing the patient in the prone position frequently is required for some surgical procedures. If cardiac arrest occurs and the patient cannot be safely turned supine, cardiopulmonary resuscitation (CPR) may need to be performed with the patient in the prone position. Although […]
Read MoreAnesthesiologists who use perioperative clonidine in the hope of reducing acute postoperative pain or opioid consumption need to reconsider their efforts. According to a randomized controlled trial at the Cleveland Clinic, in Ohio—the largest such trial ever—researchers found that the drug has neither of these perceived benefits, and its use may come at the expense […]
Read MoreAnesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 547–550 AUTHORS: Sentissi, Kinza MD et al In this prospective observational study, conducted at an academic medical center, we evaluated the feasibility of performing a basic transesophageal echocardiography (TEE) examination using endoscopic ultrasound (EUS) technology to determine what cardiac structures could be […]
Read MoreAnesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 535–546 AUTHORS: Mitrophanov, Alexander Y. PhD et al BACKGROUND: The use of prothrombin complex concentrates in trauma- and surgery-induced coagulopathy is complicated by the possibility of thromboembolic events. To explore the effects of these agents on thrombin generation (TG), we investigated combinations […]
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