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Anesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 986–995 AUTHORS: Barrachina, Borja MD et al BACKGROUND: Tranexamic acid (TXA) reduces bleeding in patients undergoing hip replacement surgery, but optimal doses and timing have yet to be established. Our primary objective in this study was to assess total blood loss 48 […]
Read MoreAnesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 976–985 AUTHORS: Grant, Michael C. MD et al BACKGROUND: Preoperative gabapentin has been shown to improve postoperative pain and limit reliance on opioid analgesia. On the basis of an alternative mechanism, our group investigated the ability of preoperative gabapentin to prevent postoperative […]
Read MoreAnesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 969–975 AUTHORS: Rascón-Martínez, Dulce M. MD et al BACKGROUND: Acute postoperative cognitive dysfunction is characterized by neurocognitive dysfunction and confusion. In this study, we compared the cognitive status of a geriatric population undergoing ophthalmic surgery, as assessed by the Short Portable Mental […]
Read MoreAnesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 953–958 AUTHORS: Whitener, George MD et al BACKGROUND: Current guidelines define severe aortic valve stenosis (AS) as an aortic valve area (AVA) ≤1.0 cm2 by the continuity equation and mean gradient (ΔPm) ≥ 40 mm Hg. However, these measurements can be discordant when […]
Read MoreAnesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 943–952 AUTHORS: Claudia Regina MD, PhD et al BACKGROUND: It is unclear whether maintaining pulmonary perfusion and ventilation during cardiopulmonary bypass (CPB) reduces pulmonary inflammatory tissue injury compared with standard CPB where the lungs are not ventilated and are minimally perfused. In […]
Read MoreAnesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 935–942 AUTHORS: Franklin, Sarah W. BA et al BACKGROUND: Bleeding is a serious complication after pediatric cardiopulmonary bypass (CPB) that is associated with an increase in perioperative morbidity and mortality. Four-factor prothrombin complex concentrates (4F-PCCs) have been used off-label to supplement transfusion […]
Read MoreAuthors: Spoletini G et al., JAMA 2016 Mar 15; High-flow oxygen and noninvasive positive pressure ventilation lowered reintubation rates in selected patient populations. During the past few years, interest has grown in using high-flow oxygen (HFO) and noninvasive positive pressure ventilation (NPPV) in lieu of intubation and mechanical ventilation (NEJM JW Gen Med Aug 1 […]
Read MoreAnesthesia & Analgesia: March 2016 AUTHORS: Buckley, Jack C. MD et al BACKGROUND: Endotracheal tube security is a critical safety issue. We compared the mobility of an in situ endotracheal tube secured with adhesive tape to the one secured with a new commercially available purpose-designed endotracheal tube-holder device (Haider Tube-Guard(R)). We also observed for the […]
Read MoreAnesthesia & Analgesia: March 2016 AUTHORS: Ghadimi, Kamrouz MD et al Prothrombin complex concentrates (PCCs) contain vitamin K-dependent clotting factors (II, VII, IX, and X) and are marketed as 3 or 4 factor-PCC formulations depending on the concentrations of factor VII. PCCs rapidly restore deficient coagulation factor concentrations to achieve hemostasis, but like with all […]
Read MoreWhether relating to health outcomes, patient perceptions of care or organizational structure, quality metrics are playing an increasingly substantive role in Medicare payment and reimbursement. As Robert S. Lagasse, MD, explained at the 2016 American Society of Anesthesiologists Practice Management annual meeting, despite the limitations of these measures, the financial stakes for physicians have never […]
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