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Anesthesiology 7 2016, Vol.125, 46-61 Authors: Frédérique Hovaguimian, M.D. et al Background: Blood transfusions are associated with morbidity and mortality. However, restrictive thresholds could harm patients less able to tolerate anemia. Using a context-specific approach (according to patient characteristics and clinical settings), the authors conducted a systematic review to quantify the effects of transfusion strategies. Methods: The authors searched MEDLINE, […]
Read MoreAnesthesiology published on 6 2016 Authors: Vanessa L. Kronzer, B.A. et al Background: No study has rigorously explored the characteristics of surgical patients with recent preoperative falls. Our objective was to describe the essential features of preoperative falls and determine whether they are associated with preoperative functional dependence and poor quality of life. Methods: This was an observational […]
Read MoreBy Carly C. Barron, MSc; Andre Y. Denault, PhD, ABIM-CCM; and Manoj M. Lalu MD, PhD Central venous catheterization is a common procedure with more than 5 million central venous catheters (CVC) implanted each year in the United States.1,2 Approximately 8% of hospitalized patients require central venous access during the course of their hospital stay.2 Appropriate […]
Read MoreBy Ian Yuan, MD, and Jeffrey M. Feldman, MD, MSE Two patients come into a hospital for elective knee replacements. Their surgeries are uneventful, but both are found to have surgical site infections in follow-up visits. In the first patient, the anesthesia professional forgets to give antibiotics prior to the start of the procedure. The […]
Read Moreby Tao Shen, MBBS, and Edward A. Bittner, MD, PhD, MSEd High tidal volume (TV) (10-15mL/kg) mechanical ventilation has been historically encouraged for anesthetized patients in the OR, especially for abdominal and thoracic procedures. This practice was based on a study published in the New England Journal of Medicine in 1963. It followed a series of 18 […]
Read Moreby Michael G Mythen, MBBS, MD, and Michael PW Grocott, BSc, MBBS, MD Fluid management is a fundamental component of the care we give our patients undergoing surgery. Establishing intravenous access and setting up a bag of fluid to flow into a vein is so much a part of everyday working life that we rarely […]
Read Moreby Todd Dodick, MD; Steven Greenberg, MD; and Michael O’Connor, MD An experienced health care provider can identify the septic patient with barely a glance, but were you to ask them to define sepsis, many providers would struggle to provide a clear definition. This difficulty likely stems from a failure of understanding of the underlying […]
Read MoreOne in seven U.S. hospitalizations among older adults is followed by an opioid prescription, and current practices of storing and disposing of these drugs are “suboptimal,” according to two JAMA Internal Medicine studies. In the first study, researchers examined nearly 625,000 Medicare beneficiaries who were hospitalized in 2011 and had no opioid prescription in the prior […]
Read MoreAnesthesiology published on 6 2016 Authors: Brian S. Rothman, M.D. et al Background: “Wrong surgery” is defined as wrong site, wrong operation, or wrong patient, with estimated incidence up to 1 per 5,000 cases. Responding to national attention on wrong surgery, our objective was to create a care redesign intervention to minimize the rate of wrong surgery. […]
Read MoreAnesthesiology published on 6 2016 Authors: Sayako Itakura, M.D. et al Background: Rapid fluid infusion resulting in increased hepatic blood flow may decrease the propofol plasma concentration (Cp) because propofol is a high hepatic extraction drug. The authors investigated the effects of rapid colloid and crystalloid infusions on the propofol Cp during target-controlled infusion. Methods: Thirty-six […]
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