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Are low-dose ketamine infusions for analgesia safe for patients who are not in a setting with continuous monitoring? The answer is yes, according to a small retrospective study. Lt. Cmdr. Jeffrey M. Carness, MD, and his colleagues at the Naval Medical Center Portsmouth, in Virginia, have long recognized the efficacy of ketamine in subanesthetic doses […]
Read MoreAmong inpatients aged 45 years or older having noncardiac surgery, 9% will experience myocardial injury within the 30 days after the procedure. About 80% of these injuries are clinically silent, detected only by troponin elevation. Mortality, however, is nearly identical for symptomatic and asymptomatic troponin elevations. Within 30 days of surgery, 10% of patients with […]
Read MorePatients receiving liposomal bupivacaine (Exparel, Pacira) injection after total knee arthroplasty (TKA) spent less time in the hospital and were significantly less likely to need to go to a rehabilitation center after discharge, a recent study found. Patients given liposomal bupivacaine spent a half-day less in the hospital than those administered routine, opioid-based pain medications, […]
Read MoreBMC Musculoskelet Disord. 2016; 17: 279. Authors: Shlomo Moshe et al Background Low back pain (LBP) is a leading cause of referral to occupational health clinics and of consequent work absenteeism. There is lack of data concerning ages 18–21. The objective of our study was to evaluate the occurrence of newly diagnosed LBP and the […]
Read MoreBMC Musculoskelet Disord. May 2016; 17: 226. Authors: Siobhán Stynes, et al Background The identification of clinically relevant subgroups of low back pain (LBP) is considered the number one LBP research priority in primary care. One subgroup of LBP patients are those with back related leg pain. Leg pain frequently accompanies LBP and is associated […]
Read MorePublished in BMC Anesthesiol. 2016;16(11) Authors: I. J. Higginson et al Background: With increasingly intensive treatments and population ageing, more people face complex treatment and care decisions. We explored patterns of the decision-making processes during critical care, and sources of conflict and resolution. Methods: Ethnographic study in two Intensive Care Units (ICUs) in an inner city hospital comprising: […]
Read MoreFor far too many years, pain researchers and clinicians have relied on the concept of the morphine equivalent daily dosage (MEDD), or some variant of it, as a means of comparing the “relative corresponding quantity” of the numerous opioid molecules that are important tools in the treatment of chronic pain. This concept dates back to […]
Read MoreVirtual reality (VR), already shown to have important benefits in the treatment of acute and procedural pain, shows preliminary evidence of also reducing symptoms in chronic pain, according to new research. “Our pain providers desperately need effective nonopioid treatments for chronic pain, ones that patients will adopt and use,” Ted Jones, PhD, from the Behavioral […]
Read MoreA mathematical model developed by researchers at Loyola University in Chicago can predict the length of time patients with hepatitis C virus (HCV) must remain on direct-acting antiviral (DAA) drugs to achieve sustained virologic response, according to a new study. The investigators used early viral kinetic analysis to test study participants—58 people with HCV being […]
Read MoreCollegium announced that the FDA has approved oxycodone (Xtampza ER) extended-release capsules, a twice-daily medication for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. The drug uses Collegium’s proprietary DETERx abuse-deterrent technology platform, and is designed to provide adequate pain control while […]
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