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Authors: Martyn Harvey, M.D., F.A.C.E.M. et al Commentary: Effect of Intralipid® on the Dose of Ropivacaine or Levobupivacaine Tolerated by Volunteers: A Clinical and Pharmacokinetic Study Anesthesiology 9 2016, Vol.125, 451-453. LORD Cyril Asquith, son of a British Prime Minister, and himself an English Law Lord, once remarked “A Judge of the first instance should be […]
Read MoreAuthor: Michael M. Todd, M.D. Commentary: Perioperative Visual Loss in Spine Fusion Surgery: Ischemic Optic Neuropathy in the United States from 1998 to 2012 in the Nationwide Inpatient Sample Anesthesiology 9 2016, Vol.125, 445-448. THE first description of postoperative visual loss (POVL) in Medline is from 1950. Cases appeared sporadically over the next 30 to 40 yr, mostly […]
Read MoreCommentary: A Multicenter, Randomized, Controlled Phase IIb Trial of Avoidance of Hyperoxemia during Cardiopulmonary Bypass Authors: Shahzad Shaefi, M.D. et al Anesthesiology 9 2016, Vol.125, 449-450. THERE are approximately 300,000 cardiac surgical procedures annually utilizing cardiopulmonary bypass (CPB) in the United States. The delivery of oxygen has been a cornerstone of anesthesia practice, with titration of oxygen therapy to […]
Read MoreAuthors: Beatrice Beck-Schimmer, M.D. et al Anesthesiology 8 2016, Vol.125, 313-321. Background: One-lung ventilation during thoracic surgery is associated with hypoxia–reoxygenation injury in the deflated and subsequently reventilated lung. Numerous studies have reported volatile anesthesia–induced attenuation of inflammatory responses in such scenarios. If the effect also extends to clinical outcome is yet undetermined. We hypothesized that volatile […]
Read MoreAuthors: M. Stephen Melton, M.D. et al Anesthesiology 8 2016, Vol.125, 368-377 Background: Limited information exists on the effects of temporary functional deafferentation (TFD) on brain activity after peripheral nerve block (PNB) in healthy humans. Increasingly, resting-state functional connectivity (RSFC) is being used to study brain activity and organization. The purpose of this study was to test […]
Read MoreNeuraxial anesthesia (NA) appears to be associated with improved overall survival (OS) in patients undergoing surgery for tumor resection, particularly in those with colorectal cancer. According to a recent meta-analysis published in Oncotarget(2016;7:15262-15273), the authors identified a correlation between the use of NA and reduced risk for cancer recurrence. The authors found significantly improved OS and […]
Read MoreFluid Management Strategy for Thoracic Surgery: The optimal range of fluid administration in patients undergoing lung resection surgery has been a controversial topic in anesthesia. There are hazards at both ends of the spectrum: Liberal over-hydration can lead to fluid-induced lung injury, while conservative fluid-management strategies have a risk for organ ischemia. According to a […]
Read MoreThe value of the services that anesthesiologists provide is being examined more closely than ever. Indeed, determining the true value of regional anesthesia can only be done within the context of its many costs, most of which are not monetary. “‘Value’ is the name of the game in medicine these days,” said Brian E. Harrington, […]
Read MoreClinical Radiology (Jul 2016) AUTHORS: O’Reilly M et al AIM To explore the morphology of neuromas and to determine the differences, if any, between asymptomatic and symptomatic neuromas using ultrasound. MATERIALS AND METHODS Eighty patients with symptomatic neuromas were included in this retrospective review. High-resolution ultrasound examination was performed. Transducer pressure allowed real-time analysis of […]
Read MoreBecause traumatically injured patients with early-onset ventilator-associated pneumonia (VAP) are more likely to be sensitive to narrow-spectrum antibiotics than those with late VAP, empirical treatment of early VAP with narrow-spectrum antibiotics is a reasonable choice, a study has found. The results also concluded that broad-spectrum antibiotics should continue to be standard empirical therapy for late […]
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