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Authors: Takashi Asai, M.D., Ph.D. Anesthesiology 10 2016, Vol.125, 615-617. REPEATED attempts at tracheal intubation increase the incidence of airway obstruction, leading to serious airway complications.1,2 Therefore, major guidelines for difficult airway management unanimously recommend avoiding repeated attempts at tracheal intubation.3–5 Much effort has been made to reduce the incidence of difficult intubation with a conventional Macintosh or […]
Read MoreAuthors: Jurgen C. de Graaff, M.D., Ph.D. et al Anesthesiology Newly Published on September 8, 2016 Background: Although noninvasive blood pressure (NIBP) monitoring during anesthesia is a standard of care, reference ranges for blood pressure in anesthetized children are not available. We developed sex- and age-specific reference ranges for NIBP in children during anesthesia and surgery. Methods: In […]
Read MoreAuthors: Wenhua Zhang, M.D. et al Anesthesiology published on September 15, 2016. Background: The median effective dose (ED50) of intranasal dexmedetomidine after failed chloral hydrate sedation has not been described for children. This study aims to determine the ED50 of intranasal dexmedetomidine for rescue sedation in children aged 1 to 36 months, who were inadequately sedated by chloral […]
Read MoreAuthors: Brian S. Rothman, M.D. et al Anesthesiology 9 2016, Vol.125, 484-494 Background: “Wrong surgery” is defined as wrong site, wrong operation, or wrong patient, with estimated incidence up to 1 per 5,000 cases. Responding to national attention on wrong surgery, our objective was to create a care redesign intervention to minimize the rate of wrong surgery. […]
Read MoreAuthors: Jacques T. YaDeau, M.D., Ph.D. et al Anesthesiology 9 2016, Vol.125, 561-572 Background: Duloxetine is effective for chronic musculoskeletal and neuropathic pain, but there are insufficient data to recommend the use of antidepressants for postoperative pain. The authors hypothesized that administration of duloxetine for 15 days would reduce pain with ambulation at 2 weeks after total […]
Read MoreAuthors: Xin-Hai Wu, M.D. et al Anesthesiology published on September 1, 2016 Background: Patients admitted to the intensive care unit (ICU) after surgery often develop sleep disturbances. The authors tested the hypothesis that low-dose dexmedetomidine infusion could improve sleep architecture in nonmechanically ventilated elderly patients in the ICU after surgery. Methods: This was a pilot, randomized controlled trial. […]
Read MoreAuthors: Philippe Sitbon, M.D. et al Anesthesiology published on September 1, 2016 Background: Opiorphin is a naturally occurring potent analgesic human peptide. It protects enkephalins from degradation and inhibits pain perception in various acute pain models via activation of endogenous opioid pathways. However, the efficacy of opiorphin continuous infusion and its chemically stable form, STR-324, in postoperative […]
Read MoreAuthors: Jessica M. Booth, M.D. et al Anesthesiology 9 2016, Vol.125, 516-524. Background: It is unclear whether recognition of epidural catheter failures is delayed with combined spinal epidural technique (CSE) compared to traditional epidural technique (EPID) when used for labor analgesia. The authors hypothesized that recognition of failed catheters is not delayed by CSE. Methods: Anesthetic, obstetric, and […]
Read MoreAleva FE et al., Chest 2016 Aug 12; This systematic review shows a high rate of PE in patients hospitalized for exacerbation of chronic obstructive pulmonary disease. Pulmonary embolism (PE) is a notoriously difficult clinical diagnosis, and symptoms of PE can overlap with those of acute exacerbations of chronic obstructive pulmonary disease (COPD). Further, the inflammation of […]
Read MoreHarlan M. Krumholz, MD, SM Reviewing McEvoy RD et al., N Engl J Med 2016 Aug 28; In a multicenter trial, patients with cardiovascular disease and obstructive sleep apnea had no reduction in risk. Continuous positive airway pressure (CPAP) is a common treatment for obstructive sleep apnea, a risk factor for cardiovascular disease. However, little is known about […]
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